Serum Immunoreactive-Leptin Concentrations in Normal-Weight and Obese Humans

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Positional cloning of the mouse obese gene and its human homologue

1994 • 12,975 citations

Enzymatic Amplification of β-Globin Genomic Sequences and Restriction Site Analysis for Diagnosis of Sickle Cell Anemia

1985 • 9,128 citations

Weight-Reducing Effects of the Plasma Protein Encoded by the obese Gene

1995 • 4,457 citations

Effects of the obese Gene Product on Body Weight Regulation in ob / ob Mice

1995 • 4,057 citations

Recombinant Mouse OB Protein: Evidence for a Peripheral Signal Linking Adiposity and Central Neural Networks

1995 • 3,302 citations

The labelling of proteins to high specific radioactivities by conjugation to a 125I-containing acylating agent. Application to the radioimmunoassay

1973 • 3,279 citations

Changes in Energy Expenditure Resulting from Altered Body Weight

1995 • 1,926 citations

The role of neuropeptide Y in the antiobesity action of the obese gene product

1995 • 1,521 citations

Overexpression of the obese (ob) gene in adipose tissue of human obese subjects

1995 • 716 citations

Increased obese mRNA expression in omental fat cells from massively obese humans

1995 • 527 citations

Induction of ob Gene Expression by Corticosteroids Is Accompanied by Body Weight Loss and Reduced Food Intake

1995 • 485 citations

Evidence against either a premature stop codon or the absence of obese gene mRNA in human obesity.

1995 • 367 citations

Methods for Voluntary Weight Loss and Control

1992 • 167 citations

Techniques for the measurement of body composition: a practical guide.

1993 • 157 citations

Enhanced Expression of Rat Obese (ob) Gene in Adipose Tissues of Ventromedial Hypothalamus-Lesioned Rats

1995 • 129 citations

Human obese gene expression. Adipocyte-specific expression and regional differences in the adipose tissue

1995 • 127 citations

Cloning of Rat Obese cDNA and Its Expression in Obese Rats

1995 • 126 citations

A new technique for biopsy of human abdominal fat under local anaesthesia with Lidocaine.

1994 • 99 citations