Activin and Inhibin Have Antagonistic Effects on Ligand-Dependent Heteromerization of the Type I and Type II Activin Receptors and Human Erythroid Differentiation

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

1983 • 52,849 citations

Signal transduction by receptors with tyrosine kinase activity

1990 • 5,528 citations

Mechanism of activation of the TGF-β receptor

1994 • 2,298 citations

Peptide Growth Factors and Their Receptors

1991 • 1,221 citations

α-lnhibin is a tumour-suppressor gene with gonadal specificity in mice

1992 • 887 citations

Expression cloning of an activin receptor, a predicted transmembrane serine kinase

1991 • 760 citations

Identification of human activin and TGFβ type I receptors that form heteromeric kinase complexes with type II receptors

1993 • 656 citations

Characterization of Type I Receptors for Transforming Growth Factor-β and Activin

1994 • 558 citations

Novel activin receptors: Distinct genes and alternative mRNA splicing generate a repertoire of serine/threonine kinase receptors

1992 • 495 citations

Type I receptors specify growth-inhibitory and transcriptional responses to transforming growth factor beta and activin.

1994 • 377 citations

Activin receptor-like kinases: a novel subclass of cell-surface receptors with predicted serine/threonine kinase activity.

1993 • 354 citations

Formation of hetero-oligomeric complexes of type I and type II receptors for transforming growth factor-beta.

1994 • 324 citations

Activation of Signalling by the Activin Receptor Complex

1996 • 317 citations

The hematopoietin receptor superfamily

1993 • 296 citations

Importance of FSH-releasing protein and inhibin in erythrodifferentiation

1987 • 275 citations

Determination of Type I Receptor Specificity by the Type II Receptors for TGF-β or Activin

1993 • 261 citations

Follistatin and Activin: A Potential Intrinsic Regulatory System within Diverse Tissues

1991 • 232 citations

Cloning of a Second Type of Activin Receptor and Functional Characterization in Xenopus Embryos

1992 • 226 citations

Activin A: an autocrine inhibitor of initiation of DNA synthesis in rat hepatocytes.

1993 • 205 citations

Paracrine Regulation of Reproductive Function by Inhibin and Activin

1992 • 172 citations

Complementation between kinase-defective and activation-defective TGF-beta receptors reveals a novel form of receptor cooperativity essential for signaling.

1996 • 158 citations

Selective and indirect modulation of human multipotential and erythroid hematopoietic progenitor cell proliferation by recombinant human activin and inhibin.

1988 • 153 citations

Expression of messenger ribonucleic acids encoding the inhibin/activin system during mid- and late-gestation rat embryogenesis.

1994 • 149 citations

Peptide Growth Factors and Their Receptors II

1990 • 142 citations

Inhibin Antagonizes Inhibition of Liver Cell Growth by Activin by a Dominant-negative Mechanism

1995 • 126 citations

Cloning and characterization of a transmembrane serine kinase that acts as an activin type I receptor.

1993 • 125 citations

Signaling by chimeric erythropoietin-TGF-beta receptors: homodimerization of the cytoplasmic domain of the type I TGF-beta receptor and heterodimerization with the type II receptor are both required for intracellular signal transduction.

1996 • 120 citations

Inhibin and activin regulate [3H]thymidine uptake by rat thymocytes and 3T3 cells in vitro

1989 • 117 citations

Biochemical evidence for the autophosphorylation and transphosphorylation of transforming growth factor beta receptor kinases.

1995 • 116 citations

Activin-A, Inhibin and Transforming Growth Factor-β Modulate Growth of Two Gonadal Cell Lines*

1989 • 100 citations

Formation and activation by phosphorylation of activin receptor complexes.

1996 • 97 citations

Characterization of type II activin receptors. Binding, processing, and phosphorylation.

1993 • 83 citations

Multiple Actions of Recombinant Activin-Ain Vivo

1989 • 82 citations

Reconstitution and transphosphorylation of TGF-beta receptor complexes.

1994 • 81 citations

Phosphorylation-dependent Interaction of the Cytoplasmic Domains of the Type I and Type II Transforming Growth Factor-β Receptors

1995 • 80 citations

Inactivation of activin-dependent transcription by kinase-deficient activin receptors.

1995 • 65 citations

Effect of activin A on globin gene expression in purified human erythroid progenitors

1992 • 55 citations

Dual effect of activin a on cell growth in Balbc 3T3 cells

1989 • 52 citations

Invivo treatment with erythroid differentiation factor (EDF / activin a) increases erythroid precursors (CFU-E and BFU-E) in mice

1989 • 45 citations

Local extragonadal roles of activins

1992 • 41 citations

Activin A‐induced diffrentiation in K562 cells is associated with a transient hypophosphorylation of RB protein and the concomitant block of cell cycle at G₁ phase

1992 • 39 citations

Effect of activin A on globin gene expression in purified human erythroid progenitors

1992 • 39 citations

Activin A suppresses proliferation of interleukin-3-responsive granulocyte-macrophage colony-forming progenitors and stimulates proliferation and differentiation of interleukin-3-responsive erythroid burst-forming progenitors in the peripheral blood

1993 • 31 citations