Drosophila cytoplasmic dynein, a microtubule motor that is asymmetrically localized in the oocyte.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

[6] Use of T7 RNA polymerase to direct expression of cloned genes

1990 • 6,681 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

1988 • 6,107 citations

Rapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primer.

1988 • 4,669 citations

Analysis of the accuracy and implications of simple methods for predicting the secondary structure of globular proteins

1978 • 4,566 citations

Predicting Coiled Coils from Protein Sequences

1991 • 3,977 citations

A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback

1989 • 2,555 citations

Complementary DNA Sequencing: Expressed Sequence Tags and Human Genome Project

1991 • 2,286 citations

Preparative and analytical purification of DNA from agarose.

1979 • 1,585 citations

The origin of pattern and polarity in the Drosophila embryo

1992 • 1,367 citations

Studies of nuclear and cytoplasmic behaviour during the five mitotic cycles that precede gastrulation in Drosophila embryogenesis

1983 • 1,034 citations

Comparison of the consensus sequence flanking translational start sites inDrosophilaand vertebrates

1987 • 966 citations

brahma: A regulator of Drosophila homeotic genes structurally related to the yeast transcriptional activator SNF2SWI2

1992 • 951 citations

[12] Unidirectional digestion with exonuclease III in DNA sequence analysis

1987 • 898 citations

Developmental genetics of oogenesis

1993 • 858 citations

A spring-loaded mechanism for the conformational change of influenza hemagglutinin

1993 • 854 citations

Affinity purification of antibodies from diazotized paper blots of heterogeneous protein samples.

1981 • 815 citations

oskar organizes the germ plasm and directs localization of the posterior determinant nanos

1991 • 804 citations

Sequence identification of 2,375 human brain genes

1992 • 764 citations

The role of localization of bicoid RNA in organizing the anterior pattern of the Drosophila embryo.

1988 • 736 citations

Tropomyosin coiled-coil interactions: Evidence for an unstaggered structure

1975 • 670 citations

staufen, a gene required to localize maternal RNAs in the Drosophila egg

1991 • 612 citations

Functional cDNA libraries from Drosophila embryos

1988 • 604 citations

oskar mRNA is localized to the posterior pole of the Drosophila oocyte

1991 • 574 citations

Vectors for Drosophila P-element-mediated transformation and tissue culture transfection

1988 • 547 citations

Female sterile mutations on the second chromosome of Drosophila melanogaster. II. Mutations blocking oogenesis or altering egg morphology.

1991 • 504 citations

Expression and function of Drosophila cyclin a during embryonic cell cycle progression

1989 • 399 citations

Reorganization of the cytoskeleton during Drosophila oogenesis: implications for axis specification and intercellular transport

1992 • 399 citations

Disruption of mitotic spindle orientation in a yeast dynein mutant.

1993 • 392 citations

A three-domain structure of kinesin heavy chain revealed by DNA sequence and microtubule binding analyses

1989 • 392 citations

Progression of the cell cycle through mitosis leads to abortion of nascent transcripts

1991 • 379 citations

Cytoplasmic dynein is required for normal nuclear segregation in yeast.

1993 • 373 citations

Role of neurogenic genes in establishment of follicle cell fate and oocyte polarity during oogenesis in Drosophila

1991 • 372 citations

chickadee encodes a profilin required for intercellular cytoplasm transport during Drosophila oogenesis

1992 • 370 citations

Organization of the cytoskeleton in early Drosophila embryos.

1986 • 352 citations

Cytoplasmic dynein is involved in nuclear migration in Aspergillus nidulans.

1994 • 352 citations

Cytoplasmic dynein plays a role in mammalian mitotic spindle formation.

1993 • 335 citations

RNA on the move: the mRNA localization pathway [published erratum appears in J Cell Biol 1993 Dec;123(6 Pt 1):1625]

1993 • 315 citations

How RNA polymerase II terminates transcription in higher eukaryotes

1989 • 301 citations

Periodic features in the amino acid sequence of nematode myosin rod

1983 • 301 citations

Transient posterior localization of a kinesin fusion protein reflects anteroposterior polarity of the Drosophila oocyte

1994 • 293 citations

Microtubules mediate the localization of bicoid RNA during Drosophila oogenesis

1991 • 255 citations

A central role for microtubules in the differentiation of Drosophila oocytes

1993 • 252 citations

cappuccino and spire: two unique maternal-effect loci required for both the anteroposterior and dorsoventral patterns of the Drosophila embryo.

1989 • 246 citations

Scanning electron microscopy of Drosophila embryogenesis

1976 • 233 citations

Multiple nucleotide-binding sites in the sequence of dynein β heavy chain

1991 • 229 citations

INTERCELLULAR MIGRATION OF CENTRIOLES IN THE GERMARIUM OF DROSOPHILA MELANOGASTER

1970 • 201 citations

Tropomyosin: Amino Acid Sequence and Coiled-Coil Structure

1973 • 197 citations

The NAM2 proteins from S. cerevisiae and S. douglasii are mitochondrial leucyl-tRNA synthetases, and are involved in mRNA splicing.

1988 • 196 citations

MOTOR PROTEINS OF CYTOPLASMIC MICROTUBULES

1990 • 196 citations

Structure of the tubulin dimer.

1977 • 182 citations

WITH APOLOGIES TO SCHEHERAZADE: TAILS OF 1001 KINESIN MOTORS

1993 • 179 citations

Bicaudal-D, a Drosophila gene involved in developmental asymmetry: localized transcript accumulation in ovaries and sequence similarity to myosin heavy chain tail domains.

1989 • 178 citations

Nuclear elongation and cytokinesis in Drosophila montana

1971 • 176 citations

Four ATP-binding sites in the midregion of the β heavy chain of dynein

1991 • 175 citations

The involvement of the Notch locus in Drosophila oogenesis

1992 • 166 citations

The Drosophila orb gene is predicted to encode sex-specific germline RNA-binding proteins and has localized transcripts in ovaries and early embryos

1992 • 165 citations

Molecular analysis of the γ heavy chain of Chlamydomonas flagellar outerarm dynein

1994 • 152 citations

Identification of microtubule-associated proteins in the centrosome, spindle, and kinetochore of the early Drosophila embryo.

1989 • 151 citations

Properties ofCommelinayellow mottle virus's complete DNA sequence, genomic discontinuities and transcript suggest that it is a pararetrovirus

1990 • 150 citations

The arflike gene encodes an essential GTP-binding protein in Drosophila.

1991 • 148 citations

A Chlamydomonas outer arm dynein mutant with a truncated beta heavy chain

1993 • 142 citations

Dynamic changes in microtubule configuration correlate with nuclear migration in the preblastoderm Drosophila embryo

1993 • 141 citations

CYTOPLASMIC MICROTUBULE-ASSOCIATED MOTORS

1993 • 137 citations

Multiple effects of colchicine on oogenesis in Drosophila: Induced sterility and switch of potential oocyte to nurse-cell developmental pathway

1983 • 136 citations

Dynein from Dictyostelium: primary structure comparisons between a cytoplasmic motor enzyme and flagellar dynein.

1992 • 129 citations

Genetic analysis of the brahma gene of Drosophila melanogaster and polytene chromosome subdivisions 72AB.

1994 • 126 citations

Characterization of the ATP-sensitive binding of Tetrahymena 30 S dynein to bovine brain microtubules.

1983 • 125 citations

Molecular cloning of the retrograde transport motor cytoplasmic dynein (MAP 1C)

1993 • 117 citations

Localized RNAs and their functions

1993 • 110 citations

Cytoplasmic microtubule-based motor proteins

1993 • 106 citations

Isolation and mapping of a cloned ribosomal protein gene of Drosophila melanogaster

1980 • 104 citations

The kinesin superfamily: tails of functional redundancy

1991 • 103 citations

Evidence for a highly selective RNA transport system and its role in establishing the dorsoventral axis of theDrosophilaegg

1992 • 96 citations

Sequence analysis of the Chlamydomonas alpha and beta dynein heavy chain genes

1994 • 93 citations

A family of dynein genes in Drosophila melanogaster.

1994 • 90 citations

Null alleles reveal novel requirements for Bic-D during Drosophila oogenesis and zygotic development

1994 • 89 citations

Motor proteins for cytoplasmic microtubules

1992 • 87 citations

An investigation of microtubule organization and functions in living Drosophila embryos by injection of a fluorescently labeled antibody against tyrosinated alpha-tubulin.

1987 • 84 citations

Enzymes for Microtubule-dependent Motility

1989 • 82 citations

Molecular analysis of the microtubule motor dynein.

1993 • 79 citations

Structure, function and regulation of cytoplasmic dynein

1994 • 79 citations

Cellular roles of kinesin and related proteins

1994 • 67 citations

The primary structure of rat brain (cytoplasmic) dynein heavy chain, a cytoplasmic motor enzyme.

1993 • 65 citations

Structure of the alpha and beta heavy chains of the outer arm dynein from Chlamydomonas flagella. Masses of chains and sites of ultraviolet-induced vanadate-dependent cleavage.

1987 • 57 citations

Molecular cloning and micleotide sequence of the gene forEscherichia colileucyl-tRNA synthetase

1987 • 51 citations

The Drosophila Cytoskeleton

1990 • 50 citations

A map of photolytic and tryptic cleavage sites on the beta heavy chain of dynein ATPase from sea urchin sperm flagella.

1988 • 41 citations

A cytoplasmic dynein motor in Drosophila: identification and localization during embryogenesis

1994 • 38 citations

Structure of the alpha and beta heavy chains of the outer arm dynein from Chlamydomonas flagella. Location of epitopes and protease-sensitive sites.

1988 • 34 citations

The role of gene cassettes in axis formation during Drosophila oogenesis

1994 • 33 citations

Molecular movements in oocyte patterning and pole cell differentiation

1992 • 20 citations

A cytoplasmic dynein heavy chain in sea urchin embryos*

1992 • 20 citations

Nuclear Gene for Mitochondrial Leucyl-tRNA Synthetase of Neurospora crassa: Isolation, Sequence, Chromosomal Mapping, and Evidence that the leu-5 Locus Specifies Structural Information

1989 • 20 citations