Nuclear Gene for Mitochondrial Leucyl-tRNA Synthetase of Neurospora crassa: Isolation, Sequence, Chromosomal Mapping, and Evidence that the leu-5 Locus Specifies Structural Information

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

“Western Blotting”: Electrophoretic transfer of proteins from sodium dodecyl sulfate-polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A

1981 • 8,657 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1984 • 4,899 citations

Unidirectional digestion with exonuclease III creates targeted breakpoints for DNA sequencing

1984 • 4,231 citations

A method for the quantitative recovery of protein in dilute solution in the presence of detergents and lipids

1984 • 3,959 citations

The scanning model for translation: an update.

1989 • 3,525 citations

Supercoil Sequencing: A Fast and Simple Method for Sequencing Plasmid DNA

1985 • 2,505 citations

A gas-liquid solid phase peptide and protein sequenator.

1981 • 2,238 citations

[4] Genetic and microbiological research techniques for Neurospora crassa

1970 • 1,111 citations

Potential Metal-Binding Domains in Nucleic Acid Binding Proteins

1986 • 1,096 citations

Mitochondrial targeting sequences may form amphiphilic helices.

1986 • 1,019 citations

Base composition-independent hybridization in tetramethylammonium chloride: a method for oligonucleotide screening of highly complex gene libraries.

1985 • 818 citations

A multiplicity of CCAAT box-binding proteins

1987 • 745 citations

Aminoacyl-tRNA Synthetases: General Features and Recognition of Transfer RNAs

1979 • 636 citations

AMINOACYL tRNA SYNTHETASES: GENERAL SCHEME OF STRUCTURE-FUNCTION RELATIONSHIPS IN THE POLYPEPTIDES AND RECOGNITION OF TRANSFER RNAS

1987 • 535 citations

Cloning and characterization of the gene for beta-tubulin from a benomyl-resistant mutant of Neurospora crassa and its use as a dominant selectable marker.

1986 • 518 citations

Efficient cloning of genes of Neurospora crassa

1986 • 465 citations

Chromosomal loci of Neurospora crassa

1982 • 344 citations

The HTS1 gene encodes both the cytoplasmic and mitochondrial histidine tRNA synthetases of S. cerevisiae

1986 • 308 citations

Amphiphilicity is essential for mitochondrial presequence function.

1988 • 274 citations

A protein required for splicing group I introns in Neurospora mitochondria is mitochondrial tyrosyl-tRNA synthetase or a derivative thereof

1987 • 265 citations

Specific Sequence Homology and Three-Dimensional Structure of an Aminoacyl Transfer RNA Synthetase

1984 • 264 citations

Participation of membrane-associated proteins in the formation of the cross-linked envelope of the keratinocyte

1984 • 257 citations

The NAM2 proteins from S. cerevisiae and S. douglasii are mitochondrial leucyl-tRNA synthetases, and are involved in mRNA splicing.

1988 • 196 citations

The yeast VAS1 gene encodes both mitochondrial and cytoplasmic valyl-tRNA synthetases.

1988 • 196 citations

Characterization of two allelic forms of Neurospora crassa laccase. Amino- and carboxyl-terminal processing of a precursor.

1988 • 194 citations

Sequence similarities among the family of aminoacyl-tRNA synthetases

1986 • 181 citations

The cross-pathway control gene of Neurospora crassa, cpc-1, encodes a protein similar to GCN4 of yeast and the DNA-binding domain of the oncogene v-jun-encoded protein.

1988 • 172 citations

Specific amino acid substitutions in bacterioopsin: Replacement of a restriction fragment in the structural gene by synthetic DNA fragments containing altered codons

1984 • 158 citations

Evidence for Dispensable Sequences Inserted into a Nucleotide Fold

1987 • 157 citations

Identification and chromosomal distribution of 5S rRNA genes in Neurospora crassa.

1985 • 150 citations

Isolation and characterization of the TRM1 locus, a gene essential for the N2,N2-dimethylguanosine modification of both mitochondrial and cytoplasmic tRNA in Saccharomyces cerevisiae.

1986 • 143 citations

Isolation and characterization of MOD5, a gene required for isopentenylation of cytoplasmic and mitochondrial tRNAs of Saccharomyces cerevisiae.

1987 • 143 citations

Silver staining of proteins in polyacrylamide gels: Increased sensitivity through a combined Coomassie blue-silver stain procedure

1985 • 136 citations

Defects in modification of cytoplasmic and mitochondrial transfer RNAs are caused by single nuclear mutations

1982 • 115 citations

Cloning and Characterization of the Gene for β-Tubulin from a Benomyl-Resistant Mutant of Neurospora crassa and Its Use as a Dominant Selectable Marker

1986 • 112 citations

Mistranslation and Ageing in Neurospora

1970 • 98 citations

Analysis of Enzyme Structure and Activity by Protein Engineering

1984 • 97 citations

Methionyl-tRNA synthetase from Escherichia coli: primary structure at the binding site for the 3'-end of tRNAfMet

1985 • 85 citations

Characterization of a yeast nuclear gene (MST1) coding for the mitochondrial threonyl-tRNA1 synthetase.

1985 • 82 citations

Three suppressor mutations which cure a mitochondrial RNA maturase deficiency occur at the same codon in the open reading frame of the nuclear NAM2 gene.

1987 • 75 citations

LINKAGE STUDIES WITH BIOCHEMICAL MUTANTS OF NEUROSPORA CRASSA

1949 • 72 citations

Structural homology in the amino-terminal domains of two aminoacyl-tRNA synthetases

1983 • 68 citations

Valyl-tRNA synthetase gene of Escherichia coli K12. Primary structure and homology within a family of aminoacyl-TRNA synthetases.

1988 • 64 citations

Methods for mycelial breakage and isolation of mitochondria and vacuoles of neurospora

1983 • 59 citations

Direct cloning of specific genomic DNA sequences in plasmid libraries following fragment enrichment

1985 • 59 citations

Molecular cloning and micleotide sequence of the gene forEscherichia colileucyl-tRNA synthetase

1987 • 51 citations

Some highlights of mitochondrial research based on analyses of Neurospora crassa mitochondrial DNA

1985 • 48 citations

AN APPARENT RELATIONSHIP BETWEEN MISTRANSLATION AND AN ALTERED LEUCYL-TRNA SYNTHETASE IN A CONDITIONAL LETHAL MUTANT OF NEUROSPORA CRASSA

1967 • 47 citations

Isolation and characterization of the yeast gene coding for the alpha subunit of mitochondrial phenylalanyl-tRNA synthetase.

1987 • 46 citations

Homology of yeast mitochondrial leucyl-tRNA synthetase and isoleucyl- and methionyl-tRNA synthetases of Escherichia coli.

1988 • 44 citations

Isolation and Characterization of MODS, a Gene Required for Isopentenylation of Cytoplasmic and Mitochondrial tRNAs of Saccharomyces cerevisiae

1987 • 41 citations

Evidence from Cassette Mutagenesis for a Structure-Function Motif in a Protein of Unknown Structure

1988 • 38 citations

Nuclear genes for cytochrome c oxidase subunits of Neurospora crassa. Isolation and characterization of cDNA clones for subunits IV, V, VI, and possibly VII.

1986 • 34 citations

Proposed involvement of an internal promoter in regulation and synthesis of mitochondrial and cytoplasmic leucyl-tRNA synthetases of Neurospora.

1977 • 29 citations

Regulation of the Nuclear Genes Encoding the Cytoplasmic and Mitochondrial Leucyl-tRNA Synthetases of Neurospora crassa

1989 • 27 citations

Mutation and ?Reversion? at the leu-5 locus of Neurospora and its effect on the cytoplasmic and mitochondrial leucyl-tRNA synthetases

1971 • 26 citations

Cytochrome Oxidase Subunit V Gene of Neurospora crassa: DNA Sequences, Chromosomal Mapping, and Evidence that the cya-4 Locus Specifies the Structural Gene for Subunit V

1989 • 23 citations

Cloning and characterization of the yeast methionyl-tRNA synthetase mutation mes1.

1987 • 17 citations

Cytoplasmic leucyl-tRNA synthetase of Neurospora crassa is not specified by the leu-5 locus.

1988 • 14 citations

Biochemical comparison of the Neurospora crassa wild‐type and the temperature‐sensitive leucine‐auxotroph mutant leu‐5

1986 • 8 citations

Biochemical comparison of the Neurospora crassa wild type and the temperature‐sensitive and leucine‐auxotroph mutant leu‐5

1986 • 7 citations

Deleted Work

1955 • 0 citations