Mycobacterium tuberculosis-Reactive CD8+ T Lymphocytes: The Relative Contribution of Classical Versus Nonclassical HLA Restriction

An essential role for interferon gamma in resistance to Mycobacterium tuberculosis infection.

1993 • 2,410 citations

Proliferating dendritic cell progenitors in human blood.

1994 • 1,922 citations

Tumor necrosis factor-α is required in the protective immune response against mycobacterium tuberculosis in mice

1995 • 1,643 citations

Restoration of Viral Immunity in Immunodeficient Humans by the Adoptive Transfer of T Cell Clones

1992 • 1,227 citations

An Antimicrobial Activity of Cytolytic T Cells Mediated by Granulysin

1998 • 1,019 citations

Major histocompatibility complex class I-restricted T cells are required for resistance to Mycobacterium tuberculosis infection.

1992 • 771 citations

THE CD1 SYSTEM: Antigen-Presenting Molecules for T Cell Recognition of Lipids and Glycolipids

1999 • 711 citations

Rapid Effector Function in CD8+ Memory T Cells

1997 • 652 citations

Immunogenicity and protective efficacy of a tuberculosis DNA vaccine

1996 • 629 citations

Differential Effects of Cytolytic T Cell Subsets on Intracellular Infection

1997 • 526 citations

Vaccination against tuberculosis by DNA injection

1996 • 513 citations

Human cytolytic and interferon γ-secreting CD8⁺T lymphocytes specific forMycobacterium tuberculosis

1998 • 364 citations

Susceptibility of Mice Deficient in CD1D or TAP1 to Infection with Mycobacterium tuberculosis

1999 • 361 citations

Fas Ligand-Induced Apoptosis of Infected Human Macrophages Reduces the Viability of IntracellularMycobacterium tuberculosis

1998 • 333 citations

CD1-restricted microbial lipid antigen-specific recognition found in the CD8+ alpha beta T cell pool.

1999 • 216 citations

CD1-Restricted Microbial Lipid Antigen-Specific Recognition Found in the CD8+ αβ T Cell Pool

1999 • 187 citations

Early Emergence of CD8⁺T Cells Primed for Production of Type 1 Cytokines in the Lungs ofMycobacterium tuberculosis-Infected Mice

1999 • 181 citations

Down-Regulation of CD1 on Antigen-Presenting Cells by Infection withMycobacterium tuberculosis

1998 • 169 citations

The course of Mycobacterium tuberculosis infection in the lungs of mice lacking expression of either perforin- or granzyme-mediated cytolytic mechanisms

1997 • 166 citations

Granulysin, a new human cytolytic granule-associated protein with possible involvement in cell-mediated cytotoxicity

1997 • 165 citations

Characterization of Human CD8+ T Cells Reactive with Mycobacterium tuberculosis–infected Antigen-presenting Cells

1998 • 163 citations

Increase in Gamma Interferon-Secreting CD8⁺, as Well as CD4⁺, T Cells in Lungs following Aerosol Infection withMycobacterium tuberculosis

1999 • 138 citations

Perforin, a cytotoxic molecule which mediates cell necrosis, is not required for the early control of mycobacterial infection in mice

1997 • 138 citations

Human alveolar T lymphocyte responses to Mycobacterium tuberculosis antigens: role for CD4+ and CD8+ cytotoxic T cells and relative resistance of alveolar macrophages to lysis.

1997 • 133 citations

Role of T Cell Subsets in Immunity against Intracellular Bacteria: Experimental Infections of Knock-Out Mice with Listeria monocytogenes and Mycobacterium bovis BCG

1994 • 127 citations

Functions and specificity of T cells following nucleic acid vaccination of mice against Mycobacterium tuberculosis infection.

1997 • 124 citations

Stimulation of human peripheral blood mononuclear cells with live Mycobacterium bovis BCG activates cytolytic CD8⁺ T cells in vitro

1996 • 120 citations

CTL Response toMycobacterium tuberculosis: Identification of an Immunogenic Epitope in the 19-kDa Lipoprotein

1998 • 116 citations

Activation of human CD8+ alpha beta TCR+ cells by Mycobacterium tuberculosis via an alternate class I MHC antigen-processing pathway.

1999 • 102 citations

Protection against tuberculosis by passive transfer with T-cell clones recognizing mycobacterial heat-shock protein 65.

1994 • 94 citations

Activation of Human CD8+ αβ TCR+ Cells byMycobacterium tuberculosisVia an Alternate Class I MHC Antigen-Processing Pathway

1999 • 83 citations

Cytotoxic T cell responses to intracellular pathogens

1998 • 68 citations

Suppression of T-cell proliferation by Mycobacterium leprae and its products: the role of lipopolysaccharide.

1990 • 49 citations

Immune Responses in Animal Models

1996 • 21 citations