Systems medicine and integrated care to combat chronic noncommunicable diseases

Genetics of Food Intake Self-Regulation in Childhood: Literature Review and Research Opportunities

2013 • 7,434 citations

Closing the gap in a generation: health equity through action on the social determinants of health

2008 • 7,092 citations

Decision aids for people facing health treatment or screening decisions

2017 • 5,957 citations

Network medicine: a network-based approach to human disease

2010 • 4,396 citations

Early-warning signals for critical transitions

2009 • 3,950 citations

OTTAWA CHARTER FOR HEALTH PROMOTION

1986 • 3,753 citations

Expert Panel Report 3: Guidelines for the Diagnosis and Management of Asthma

2007 • 3,509 citations

Ageing populations: the challenges ahead

2009 • 3,360 citations

Clinical Practice Guidelines and Quality of Care for Older Patients With Multiple Comorbid Diseases

2005 • 2,397 citations

Collaborative Care for Patients with Depression and Chronic Illnesses

2010 • 1,567 citations

Defining Comorbidity: Implications for Understanding Health and Health Services

2009 • 1,475 citations

Closing the gap in a generation: health equity through action on the social determinants of health

2009 • 1,398 citations

Systems Biology and New Technologies Enable Predictive and Preventative Medicine

2004 • 1,088 citations

Multiple Chronic Conditions: Prevalence, Health Consequences, and Implications for Quality, Care Management, and Costs

2007 • 1,074 citations

The burden of non-communicable diseases in South Africa

2009 • 970 citations

Achieving health equity: from root causes to fair outcomes

2007 • 869 citations

Prevalence of parkinsonism and Parkinson's disease in Europe: the EUROPARKINSON Collaborative Study. European Community Concerted Action on the Epidemiology of Parkinson's disease.

1997 • 835 citations

Statistical strategies for avoiding false discoveries in metabolomics and related experiments

2006 • 759 citations

Predictive, personalized, preventive, participatory (P4) cancer medicine

2011 • 759 citations

Interventions for improving the adoption of shared decision making by healthcare professionals.

2010 • 741 citations

Uniform definition of asthma severity, control, and exacerbations: Document presented for the World Health Organization Consultation on Severe Asthma

2010 • 705 citations

Decision aids for people facing health treatment or screening decisions

2009 • 679 citations

Monitoring and surveillance of chronic non-communicable diseases: progress and capacity in high-burden countries

2010 • 669 citations

Global Surveillance, Prevention and Control of Chronic Respiratory Diseases: A Comprehensive Approach

2008 • 485 citations

Global surveillance, prevention and control of chronic respiratory diseases: a comprehensive approach.

2007 • 454 citations

Biomass Fuels and Respiratory Diseases: A Review of the Evidence

2008 • 453 citations

Early life origins of chronic obstructive pulmonary disease

2009 • 441 citations

Dysregulation of lipid and amino acid metabolism precedes islet autoimmunity in children who later progress to type 1 diabetes

2008 • 436 citations

A 10 year asthma programme in Finland: major change for the better

2006 • 432 citations

Integrated care: a position paper of the WHO European Office for Integrated Health Care Services.

2001 • 414 citations

Systems medicine: the future of medical genomics and healthcare

2009 • 386 citations

Comorbidity: Implications for the Importance of Primary Care in 'Case' Management

2003 • 366 citations

The effectiveness of interprofessional education: Key findings from a new systematic review

2010 • 351 citations

Genes, environment and the value of prospective cohort studies

2006 • 311 citations

Global Noncommunicable Diseases — Where Worlds Meet

2010 • 297 citations

Collaborative Care for Patients with Depression and Chronic Illnesses

2011 • 285 citations

A systems approach to prion disease

2009 • 280 citations

Dietary Intervention in Infancy and Later Signs of Beta-Cell Autoimmunity

2010 • 278 citations

Tackling Chronic Disease in Europe: Strategies, Interventions and Challenges

2010 • 267 citations

Clinical Effects of Home Telemonitoring in the Context of Diabetes, Asthma, Heart Failure and Hypertension: A Systematic Review

2010 • 265 citations

Effects of communicating DNA-based disease risk estimates on risk-reducing behaviours

2010 • 255 citations

Systems medicine and integrated care to combat chronic noncommunicable diseases

2011 • 245 citations

Comorbidity and guidelines: conflicting interests

2006 • 244 citations

Agricultural Biodiversity, Nutrition, and Health: Making a Difference to Hunger and Nutrition in the Developing World

2006 • 243 citations

The Emergence of Translational Epidemiology: From Scientific Discovery to Population Health Impact

2010 • 240 citations

Risk of severe asthma episodes predicted from fluctuation analysis of airway function

2005 • 216 citations

Translating Research Evidence Into Practice to Reduce Health Disparities: A Social Determinants Approach

2010 • 191 citations

Addressing the Complexity of Chronic Obstructive Pulmonary Disease

2010 • 183 citations

Offspring of diabetic pregnancy: Long-term outcomes

2009 • 180 citations

Ageing populations: the challenges ahead

2010 • 172 citations

Predictive, preventive, personalized and participatory medicine: back to the future

2010 • 171 citations

MeDALL (Mechanisms of the Development of ALLergy): an integrated approach from phenotypes to systems medicine

2011 • 167 citations

The Experience of Pay for Performance in English Family Practice: A Qualitative Study

2008 • 163 citations

Diabetes and vessel wall remodelling: from mechanistic insights to regenerative therapies

2008 • 148 citations

An Integrative Systems Biology Approach to Understanding Pulmonary Diseases

2010 • 140 citations

Best-practice interventions to reduce socioeconomic inequalities of coronary heart disease mortality in UK: a prospective occupational cohort study

2008 • 137 citations

Medical Homes

2009 • 124 citations

The hygiene hypothesis and the increasing prevalence of chronic inflammatory disorders

2007 • 121 citations

Type 2 Diabetes

2015 • 116 citations

Health, agricultural, and economic effects of adoption of healthy diet recommendations

2010 • 116 citations

Type 2 Diabetes

2010 • 106 citations

Biomedical informatics and translational medicine

2010 • 101 citations

Epigenetic inheritance of fetal genes in allergic asthma

2004 • 99 citations

Development and implementation of guidelines in allergic rhinitis – an ARIA‐GA²LEN paper

2010 • 97 citations

Effective knowledge management in translational medicine

2010 • 93 citations

Impact of communicating personalized genetic risk information on perceived control over the risk: A systematic review

2010 • 88 citations

In Utero Life and Epigenetic Predisposition for Disease

2010 • 83 citations

Toward a Consensus on Guiding Principles for Health Systems Strengthening

2010 • 74 citations

Re-visioning Public Health Ethics: A Relational Perspective

2010 • 70 citations

The science of primary health-care improvement: potential and use of community-based participatory research by practice-based research networks for translation of research into practice

2010 • 68 citations

Drug Discovery in a Multidimensional World: Systems, Patterns, and Networks

2010 • 64 citations

Access to inhaled corticosteroids is key to improving quality of care for asthma in developing countries

2007 • 62 citations

Global Economic and Health Benefits of Tobacco Control: Part 2

2009 • 60 citations

Emerging landscape of genomics in the electronic health record for personalized medicine

2011 • 58 citations

Informatics and Medicine

2008 • 53 citations

Ethnogenetic layering (EL): an alternative to the traditional race model in human variation and health disparity studies

2008 • 52 citations

Coronary Heart Disease: A Disorder of Growth

2003 • 52 citations

Finding common ground? Evaluating an intervention to improve teamwork among primary health-care professionals

2010 • 49 citations

Fluctuations and determinism of respiratory impedance in asthma and chronic obstructive pulmonary disease

2010 • 47 citations

The Ultimate Model Organism

2008 • 46 citations

Health-systems strengthening: current and future activities

2010 • 44 citations

Bioinformatics: Towards New Directions for Public Health

2004 • 40 citations

From Systems Biology to Systems Medicine

2020 • 33 citations

Allergy is rare where butterflies flourish in a biodiverse environment

2009 • 24 citations

Daily functioning of dyspnea, self-esteem and physical self in patients with moderate COPD before, during and after a first inpatient rehabilitation program

2007 • 21 citations

Training and application of community-oriented primary care (COPC) through family medicine in Catalonia, Spain.

2008 • 17 citations

Sharing knowledge: a new frontier for public-private partnerships in medicine

2009 • 8 citations

INFOBIOMED: European Network of Excellence on Biomedical Informatics to support individualised healthcare.

2005 • 4 citations