Clinical Pharmacology of the Fluoroquinolones: Studies in Human Dynamic/Kinetic Models

State‐of‐the‐Art Clinical Article: Pharmacokinetic/Pharmacodynamic Parameters: Rationale for Antibacterial Dosing of Mice and Men

1998 • 2,792 citations

Pharmacodynamics of intravenous ciprofloxacin in seriously ill patients

1993 • 1,093 citations

Pharmacodynamics of Levofloxacin

1998 • 583 citations

Pharmacodynamic Evaluation of Factors Associated with the Development of Bacterial Resistance in Acutely Ill Patients during Therapy

1998 • 521 citations

The Importance of Pharmacokinetic/Pharmacodynamic Surrogate Markers to Outcome

1995 • 369 citations

Pharmacokinetics, Safety, and Tolerability of Ascending Single Doses of Moxifloxacin, a New 8-Methoxy Quinolone, Administered to Healthy Subjects

1998 • 292 citations

Pharmacokinetics and Pharmacodynamics of Fluoroquinolones

1999 • 281 citations

Expanded activity and utility of the new fluoroquinolones: A review

1999 • 211 citations

Azithromycin: 3-Day Versus 5-Day Course in the Treatment of Respiratory Tract Infections in Children

1997 • 205 citations

Mathematical Examination of Dual Individualization Principles (I): Relationships between AUC above MIC and Area under the Inhibitory Curve for Cefmenoxime, Ciprofloxacin, and Tobramycin

1991 • 145 citations

Pharmacokinetics and pharmacodynamics of oral grepafloxacin in patients with acute bacterial exacerbations of chronic bronchitis

1997 • 135 citations

Pharmacodynamics and pharmacokinetics of antibiotics with special reference to the fluoroquinolones

1991 • 128 citations

Cerebrovascular accident complicating acute myocardial infarction: Incidence, clinical significance, and short-long-term mortality rates

1991 • 75 citations

Clinical Significance of Antibiotic Tissue Penetration

1989 • 71 citations

Two Pharmacodynamic Models for Assessing the Efficacy of Amoxicillin-Clavulanate against Experimental Respiratory Tract Infections Caused by Strains of Streptococcus pneumoniae

1999 • 60 citations

Pharmacodynamics of Fluoroquinolones in Experimental Models of Endocarditis

1998 • 60 citations

Mathematical Examination of Dual Individualization Principles (II): The Rate of Bacterial Eradication at the Same Area under the Inhibitory Curve is More Rapid for Ciprofloxacin Than for Cefmenoxime

1994 • 59 citations

Comparison of Pharmacodynamics of Azithromycin and Erythromycin In Vitro and In Vivo

1998 • 51 citations

Pharmacodynamic activities of ciprofloxacin and sparfloxacin in a murine pneumococcal pneumonia model: relevance for drug efficacy.

1998 • 35 citations

Use of Serum Ultrafiltrate in the Serum Dilution Test

1989 • 21 citations

Untitled

1999 • 5 citations