Mathematical Examination of Dual Individualization Principles (II): The Rate of Bacterial Eradication at the Same Area under the Inhibitory Curve is More Rapid for Ciprofloxacin Than for Cefmenoxime

Pharmacodynamics of intravenous ciprofloxacin in seriously ill patients

1993 • 1,093 citations

Antibacterial Activity in Serum and Urine as a Therapeutic Guide in Bacterial Infections

1974 • 238 citations

Opportunities for integration of pharmacokinetics, pharmacodynamics, and toxicokinetics in rational drug development

1992 • 194 citations

Antibiotic tissue penetration and its relevance: impact of tissue penetration on infection response

1991 • 175 citations

Evaluation of Intravenous Ciprofloxacin in Patients With Nosocomial Lower Respiratory Tract Infections

1989 • 169 citations

Candidiasis in the transplant patient.

1984 • 149 citations

Mathematical Examination of Dual Individualization Principles (I): Relationships between AUC above MIC and Area under the Inhibitory Curve for Cefmenoxime, Ciprofloxacin, and Tobramycin

1991 • 145 citations

Development of a population pharmacokinetic model and optimal sampling strategies for intravenous ciprofloxacin

1993 • 137 citations

Antibiotic tissue penetration and its relevance: models of tissue penetration and their meaning

1991 • 137 citations

Comparative dose-effect relations at several dosing intervals for beta-lactam, aminoglycoside and quinolone antibiotics against gram-negative bacilli in murine thigh-infection and pneumonitis models.

1990 • 135 citations

Role for Dual Individualization with Cefmenoxime

1984 • 132 citations

The inhibitory quotient. A method for interpreting minimum inhibitory concentration data

1981 • 127 citations

Serum Bactericidal Activity as a Monitor of Antibiotic Therapy

1985 • 126 citations

The mode of action of 4-quinolones and possible mechanisms of resistance

1986 • 123 citations

Antimicrobial Therapy

1985 • 101 citations

The Inhibitory Quotient

1981 • 92 citations

Survival: A Supplementary Module for SYSTAT

1989 • 77 citations

Clinical Significance of Antibiotic Tissue Penetration

1989 • 71 citations

Value of serum tests in combined drug therapy of endocarditis

1983 • 41 citations

Dual individualization of intravenous ciprofloxacin in patients with nosocomial lower respiratory tract infections.

1987 • 37 citations

Cefmenoxime Efficacy, Safety, and Pharmacokinetics in Critical Care Patients with Nosocomial Pneumonia

1984 • 35 citations

Effect of dose and schedule on cefoperazone pharmacodynamics in an in Vitro model of infection in a neutropenic host

1988 • 21 citations

Mathematical Examination of Dual Individualization Principles (III): Development of a Scoring System for Pneumonia Staging and Quantitation of Response to Antibiotics: Results in Cefmenoxime-Treated Patients

1992 • 11 citations

Pharmacokinetic and microbiologic evaluation of dosage regimens for newer cephalosporins and penicillins.

1983 • 9 citations