Protection of Mice againstPlasmodium yoeliiSporozoite Challenge withP. yoeliiMerozoite Surface Protein 1 DNA Vaccines

Guide for the Care and Use of Laboratory Animals

2011 • 15,863 citations

Universally immunogenic T cell epitopes: promiscuous binding to human MHC class II and promiscuous recognition by T cells

1989 • 706 citations

Immunization against blood-stage rodent malaria using purified parasite antigens

1981 • 400 citations

An Improved Plasmid DNA Expression Vector for Direct Injection into Skeletal Muscle

1996 • 336 citations

Merozoite surface coat precursor protein completely protects Aotus monkeys against Plasmodium falciparum malaria.

1987 • 311 citations

Induction of protective immunity against experimental infection with malaria using synthetic peptides

1987 • 282 citations

Circumventing genetic restriction of protection against malaria with multigene DNA immunization: CD8+ cell-, interferon gamma-, and nitric oxide-dependent immunity.

1996 • 257 citations

Immunogenicity and In Vivo Efficacy of Recombinant Plasmodium falciparum Merozoite Surface Protein-1 in Aotus Monkeys

1995 • 189 citations

A recombinant 15-kilodalton carboxyl-terminal fragment of Plasmodium yoelii yoelii 17XL merozoite surface protein 1 induces a protective immune response in mice

1993 • 189 citations

A recombinant baculovirus 42-kilodalton C-terminal fragment of Plasmodium falciparum merozoite surface protein 1 protects Aotus monkeys against malaria

1996 • 182 citations

Immunization against malaria with a recombinant protein

1994 • 182 citations

Humoral response to a carboxyl-terminal region of the merozoite surface protein-1 plays a predominant role in controlling blood-stage infection in rodent malaria.

1995 • 171 citations

Use of human universally antigenic tetanus toxin T cell epitopes as carriers for human vaccination.

1992 • 135 citations

An OspA-Based DNA Vaccine Protects Mice against Infection with Borrelia burgdorferi

1997 • 107 citations

Ability of recombinant or native proteins to protect monkeys against heterologous challenge with Plasmodium falciparum

1991 • 103 citations

Protection against malaria in Aotus monkeys immunized with a recombinant blood-stage antigen fused to a universal T-cell epitope: correlation of serum gamma interferon levels with protection

1992 • 84 citations

A protective monoclonal antibody recognizes an epitope in the carboxyl-terminal cysteine-rich domain in the precursor of the major merozoite surface antigen of the rodent malarial parasite, Plasmodium yoelii.

1989 • 77 citations

Genetic regulation of protective immune response in congenic strains of mice vaccinated with a subunit malaria vaccine.

1996 • 69 citations

Cloning and analysis of the gene encoding the 230-kilodalton merozoite surface antigen of Plasmodium yoelii

1989 • 69 citations

Characteristics of the protective response of BALB/c mice immunized with a purified Plasmodium yoelii schizont antigen.

1983 • 63 citations

The major merozoite surface protein as a malaria vaccine target

1993 • 59 citations

Influence of adjuvants on protection induced by a recombinant fusion protein against malarial infection

1996 • 51 citations

Comparison of protection induced by immunization with recombinant proteins from different regions of merozoite surface protein 1 of Plasmodium yoelii

1997 • 43 citations

Protection of aouts monkeys after immunization with recombinant antigens of Plasmodium falciparum

1992 • 12 citations

Protective efficacy against malaria of a combination sporozoite and erythrocytic stage vaccine

1996 • 11 citations