Breakdown of Tolerance to a Neo-Self Antigen in Double Transgenic Mice in Which B Cells Present the Antigen

Fas Ligand-Induced Apoptosis as a Mechanism of Immune Privilege

1995 • 2,028 citations

Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice

1988 • 1,562 citations

Antigen-specific interaction between T and B cells

1985 • 1,396 citations

Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes

1989 • 1,015 citations

Elimination from peripheral lymphoid tissues of self-reactive B lymphocytes recognizing membrane-bound antigens

1991 • 694 citations

Developmental Biology of T Cells in T Cell-Receptor Transgenic Mice

1990 • 637 citations

Transgenic Mice and Analysis of B-Cell Tolerance

1992 • 362 citations

Unraveling Immune Privilege

1995 • 302 citations

The role of FasL-induced apoptosis in immune privilege

1997 • 262 citations

alpha A-crystallin is expressed in non-ocular tissues

1992 • 251 citations

A novel role for TGF-beta and IL-10 in the induction of immune privilege.

1998 • 241 citations

I-Ag7-mediated antigen presentation by B lymphocytes is critical in overcoming a checkpoint in T cell tolerance to islet beta cells of nonobese diabetic mice.

1999 • 228 citations

Immunoreactive αA crystallin in rat non-lenticular tissues detected with a sensitive immunoassay method

1991 • 220 citations

Effect of antigen/antibody ratio on macrophage uptake, processing, and presentation to T cells of antigen complexed with polyclonal antibodies.

1991 • 212 citations

Induction of Self-Rolerance in T Cells But Not B Cells of Transgenic Mice Expressing Little Self Antigen

1991 • 211 citations

I-Ag7-Mediated Antigen Presentation by B Lymphocytes Is Critical in Overcoming a Checkpoint in T Cell Tolerance to Islet β Cells of Nonobese Diabetic Mice

1999 • 190 citations

Peptide Dose, Affinity, and Time of Differentiation Can Contribute to the Th1/Th2 Cytokine Balance

1999 • 182 citations

A Novel Role for TGF-β and IL-10 in the Induction of Immune Privilege

1998 • 178 citations

A Range of CD4 T Cell Tolerance: Partial Inactivation to Organ-Specific Antigen Allows Nondestructive Thyroiditis or Insulitis

1997 • 178 citations

Prevention of experimental allergic encephalomyelitis in rats by targeting autoantigen to B cells: evidence that the protective mechanism depends on changes in the cytokine response and migratory properties of the autoantigen-specific T cells.

1995 • 150 citations

Dendritic Cell Immunization Breaks Cytotoxic T Lymphocyte Tolerance in Hepatitis B Virus Transgenic Mice

1998 • 147 citations

Non‐Deletional Mechanisms of Peripheral and Central Tolerance: Studies with Transgenic Mice with Tissue‐Specific Expression of a Foreign MHC Class I Antigen

1991 • 107 citations

Mechanisms of tolerance to self

1996 • 94 citations

Membrane and soluble Fc gamma RII/III modulate the antigen-presenting capacity of murine dendritic epidermal Langerhans cells for IgG-complexed antigens.

1995 • 82 citations

Self-reactive B Cells Are Not Eliminated or Inactivated by Autoantigen Expressed on Thyroid Epithelial Cells

1997 • 70 citations

Effect of gamma radiation on resting B lymphocytes. II. Functional characterization of the antigen-presentation defect.

1988 • 64 citations

Dose‐dependent T cell tolerance to an immunodominant self peptide

1994 • 57 citations

A Transgenic Approach to the Study of Peripheral T‐Cell Tolerance

1991 • 54 citations

B-cell tolerance

1992 • 49 citations

Transgenic Mouse Models of Self-Tolerance and Autoreactivity by the Immune System

1990 • 38 citations

Immunotolerance against a foreign antigen transgenically expressed in the lens.

1998 • 37 citations

Dissociation between humoral and cellular immune responses to lens antigens.

1981 • 35 citations

Hen egg-white lysozyme-specific T cells elicited in hen egg-white lysozyme-transgenic mice retain an imprint of self-tolerance.

1993 • 35 citations

The immune response to homologous lens crystallin. I. Antibody production after lens injury.

1982 • 22 citations

Immune responses to peptides derived from the retinal protein IRBP: Immunopathogenic determinants are not necessarily immunodominant

1989 • 18 citations

Uveitis induced by lymphocytes sensitized against a transgenically expressed lens protein.

1999 • 17 citations

Transgenic Mice as an in vivo Model for Self‐Reactivity

1990 • 16 citations

Anergic B cells constitutively present self antigen: Enhanced immunoglobulin receptor‐mediated presentation of antigenic determinants by B cells is hierarchical

1994 • 14 citations

mAb against hen egg-white lysozyme regulate its presentation to CD4+ T cells

1999 • 10 citations

Immune Responses against Self-TCR Peptides

1994 • 6 citations

Antibody production after lens injury.

1982 • 4 citations