Influenza Virus PB1-F2 Protein Induces Cell Death through Mitochondrial ANT3 and VDAC1

Efficient selection for high-expression transfectants with a novel eukaryotic vector

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tBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome c

2000 • 1,245 citations

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2004 • 1,045 citations

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2001 • 1,035 citations

A novel influenza A virus mitochondrial protein that induces cell death

2001 • 1,006 citations

Influenza A Virus Lacking the NS1 Gene Replicates in Interferon-Deficient Systems

1998 • 985 citations

Breaking the mitochondrial barrier

2001 • 947 citations

VDAC2 Inhibits BAK Activation and Mitochondrial Apoptosis

2003 • 789 citations

Bmf: A Proapoptotic BH3-Only Protein Regulated by Interaction with the Myosin V Actin Motor Complex, Activated by Anoikis

2001 • 620 citations

Chimeric green fluorescent protein as a tool for visualizing subcellular organelles in living cells

1995 • 493 citations

The Adenine Nucleotide Translocase: A Central Component of the Mitochondrial Permeability Transition Pore and Key Player in Cell Death

2003 • 491 citations

The HIV-1 Viral Protein R Induces Apoptosis via a Direct Effect on the Mitochondrial Permeability Transition Pore

2000 • 449 citations

Apoptosis: a mechanism of cell killing by influenza A and B viruses

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A cytomegalovirus-encoded mitochondria-localized inhibitor of apoptosis structurally unrelated to Bcl-2

1999 • 422 citations

The virus battles: IFN induction of the antiviral state and mechanisms of viral evasion

2001 • 420 citations

Mitochondrial intermembrane proteins in cell death

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Complexes between porin, hexokinase, mitochondrial creatine kinase and adenylate translocator display properties of the permeability transition pore. Implication for regulation of permeability transition by the kinases

1998 • 342 citations

Caspase 3 activation is essential for efficient influenza virus propagation

2003 • 332 citations

Inhibition of Interferon-Mediated Antiviral Responses by Influenza A Viruses and Other Negative-Strand RNA Viruses

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Differential expression of adenine nucleotide translocator isoforms in mammalian tissues and during muscle cell differentiation.

1992 • 316 citations

Hepatitis B Virus X Protein Colocalizes to Mitochondria with a Human Voltage-Dependent Anion Channel, HVDAC3, and Alters Its Transmembrane Potential

2000 • 306 citations

Hepatitis B virus HBx protein sensitizes cells to apoptotic killing by tumor necrosis factor α

1997 • 302 citations

Proapoptotic BH3-only Bcl-2 family members induce cytochromecrelease, but not mitochondrial membrane potential loss, and do not directly modulate voltage-dependent anion channel activity

2000 • 273 citations

Control of Mitochondrial Membrane Permeabilization by Adenine Nucleotide Translocator Interacting with HIV-1 Viral Protein R and Bcl-2

2001 • 269 citations

Tumor Necrosis Factor Alpha Exerts Powerful Anti-Influenza Virus Effects in Lung Epithelial Cells

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Cloning and functional expression in yeast of two human isoforms of the outer mitochondrial membrane channel, the voltage-dependent anion channel.

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Bongkrekic Acid

1970 • 236 citations

The Influenza A Virus PB1-F2 Protein Targets the Inner Mitochondrial Membrane via a Predicted Basic Amphipathic Helix That Disrupts Mitochondrial Function

2003 • 214 citations

Involvement of FADD and caspase-8 signalling in detachment-induced apoptosis

1999 • 209 citations

The function of complexes between the outer mitochondrial membrane pore (VDAC) and the adenine nucleotide translocase in regulation of energy metabolism and apoptosis.

2003 • 183 citations

Evidence for a function of death-receptor-related, death-domain-containing proteins in anoikis

1999 • 172 citations

Neisseria meningitidisporin PorB interacts with mitochondria and protects cells from apoptosis

2000 • 170 citations

Pro-apoptotic Cleavage Products of Bcl-xL Form Cytochrome c-conducting Pores in Pure Lipid Membranes

2001 • 139 citations

Influenza A virus replication is dependent on an antioxidant pathway that involves GSH and Bcl‐2

2003 • 134 citations

PB1-F2, an Influenza A Virus-Encoded Proapoptotic Mitochondrial Protein, Creates Variably Sized Pores in Planar Lipid Membranes

2004 • 133 citations

Targeting of the pro-apoptotic VDAC-like porin (PorB) of Neisseria gonorrhoeae to mitochondria of infected cells

2000 • 133 citations

Tissue‐specific transcription pattern of the adenine nucleotide translocase isoforms in humans

1997 • 122 citations

Mitochondrial targeting sequence of the influenza A virus PB1‐F2 protein and its function in mitochondria

2004 • 122 citations

NEW EMBO MEMBERS' REVIEW: Viral and bacterial proteins regulating apoptosis at the mitochondrial level

2001 • 117 citations

bcl-2 alters influenza virus yield, spread, and hemagglutinin glycosylation

1996 • 112 citations

The Myxoma Poxvirus Protein, M11L, Prevents Apoptosis by Direct Interaction with the Mitochondrial Permeability Transition Pore

2002 • 99 citations

Translocation of Full-length Bid to Mitochondria during Anoikis

2004 • 99 citations

Cell permeable BH3-peptides overcome the cytoprotective effect of Bcl-2 and Bcl-XL

2002 • 91 citations

INFLUENZA VIRUS INDUCTION OF APOPTOSIS BY INTRINSIC AND EXTRINSIC MECHANISMS

2003 • 89 citations

Influenza A virus-induced apoptosis in bronchiolar epithelial (NCI-H292) cells limits pro-inflammatory cytokine release

2003 • 82 citations

Mitochondrion-targeted apoptosis regulators of viral origin

2003 • 57 citations

VDAC and peripheral channelling complexes in health and disease

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[Identification of human porins. II. Characterization and primary structure of a 31-lDa porin from human B lymphocytes (Porin 31HL)].

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Influenza A virus protein PB1-F2: synthesis and characterization of the biologically active full length protein and related peptides

2005 • 25 citations