Perspectives on the synthesis and application of triple-helical, collagen-model peptides

COLLAGENS: Molecular Biology, Diseases, and Potentials for Therapy

1995 • 1,599 citations

Cell Biology of Extracellular Matrix

1988 • 1,498 citations

Progress in polymer science

1972 • 1,358 citations

Crystal and Molecular Structure of a Collagen-Like Peptide at 1.9 Å Resolution

1994 • 1,043 citations

Stability of proteins. Proteins which do not present a single cooperative system.

1982 • 1,041 citations

Type I macrophage scavenger receptor contains α-helical and collagen-like coiled coils

1990 • 1,039 citations

The MIDAS display system

1988 • 955 citations

Stability of Proteins

1982 • 718 citations

Chemistry and Biology of Peptides

1972 • 616 citations

Heritable Diseases of Collagen

1984 • 572 citations

Cloning of a novel bacteria-binding receptor structurally related to scavenger receptors and expressed in a subset of macrophages

1995 • 501 citations

Coiled-coil fibrous domains mediate ligand binding by macrophage scavenger receptor type II

1990 • 460 citations

Integrin α2β1-independent activation of platelets by simple collagen-like peptides: collagen tertiary (triple-helical) and quaternary (polymeric) structures are sufficient alone for α2β1-independent platelet reactivity

1995 • 311 citations

A cell surface receptor complex for collagen type I recognizes the Arg-Gly-Asp sequence.

1987 • 302 citations

Synthesis of (Pro-Hyp-Gly)n of defined molecular weights Evidence for the stabilization of collagen triple helix by hydroxypyroline

1973 • 291 citations

The Zipper-Like Folding Of Collagen Triple Helices And The Effects Of Mutations That Disrupt The Zipper

1991 • 262 citations

Charged collagen structure mediates the recognition of negatively charged macromolecules by macrophage scavenger receptors.

1993 • 243 citations

The triple helix ⇌ coil conversion of collagen‐like polytripeptides in aqueous and nonaqueous solvents. Comparison of the thermodynamic parameters and the binding of water to (<scp>L</scp>‐Pro‐<scp>L</scp>‐Pro‐Gly)_n and (<scp>L</scp>‐Pro‐<scp>L</scp>‐Hyp‐Gly)_n

1977 • 214 citations

Molecular conformation and packing in collagen fibrils

1983 • 179 citations

Crystal and molecular structure of a collagen-like polypeptide (Pro-Pro-Gly)10

1981 • 176 citations

Promotion of Fibroblast Adhesion by Triple-helical Peptide Models of Type I Collagen-derived Sequences

1996 • 176 citations

Electrostatic Interactions in Collagen-like Triple-Helical Peptides

1994 • 169 citations

Mutations that alter the primary structure of type I collagen. The perils of a system for generating large structures by the principle of nucleated growth.

1990 • 163 citations

Structures and high and low affinity ligand binding properties of murine type I and type II macrophage scavenger receptors

1993 • 155 citations

The collagenous domains of macrophage scavenger receptors and complement component C1q mediate their similar, but not identical, binding specificities for polyanionic ligands.

1993 • 150 citations

Synthesis of Poly-(<scp>l</scp>-prolyl-<scp>l</scp>-prolylglycyl) of Defined Molecular Weights

1968 • 148 citations

Characterization of collagen-like peptides containing interruptions in the repeating Gly-X-Y sequence

1993 • 137 citations

Delayed Triple Helix Formation of Mutant Collagen from Patient with Osteogenesis Imperfecta

1994 • 130 citations

A high‐resolution ¹³C‐nmr study of collagenlike polypeptides and collagen fibrils in solid state studied by the cross‐polarization–magic angle‐spinning method. Manifestation of conformation‐dependent ¹³C chemical shifts and application to conformational characterization

1984 • 122 citations

Two-dimensional NMR assignments and conformation of (Pro-Hyp-Gly)10 and a designed collagen triple-helical peptide

1993 • 116 citations

Physicochemical analysis of (Pro‐Pro‐Gly)_n with defined molecular weight–temperature dependence of molecular weight in aqueous solution

1970 • 114 citations

Melanoma cell adhesion and spreading activities of a synthetic 124-residue triple-helical “mini-collagen”

1993 • 113 citations

Effects of the stereo-configuration of the hydroxyl group in 4-hydroxyproline on the triple-helical structures formed by homogeneous peptides resembling collagen

1976 • 104 citations

Synthesis and physical properties of (hydroxyproline-proline-glycine)10: Hydroxyproline in the X-position decreases the melting temperature of the collagen triple helix

1982 • 103 citations

Solid‐Phase synthesis and stability of triple‐helical peptides incorporating native collagen sequences

1993 • 102 citations

Determination of backbone dynamics of (Pro-Hyp-Gly)10 and a designed collagen-like triple-helical peptide by nitrogen-15 NMR relaxation and hydrogen-exchange measurements

1993 • 90 citations

Synthesis and investigation of collagen model peptides

1982 • 84 citations

Promotion of cell adhesion by single-stranded and triple-helical peptide models of basement membrane collagen alpha 1(IV)531-543. Evidence for conformationally dependent and conformationally independent type IV collagen cell adhesion sites.

1994 • 83 citations

Protocollagen lysine hydroxylase. Hydroxylation of synthetic peptides and the stoichiometric decarboxylation of α-ketoglutarate

1972 • 83 citations

Collagen

1991 • 78 citations

Single crystals of (Pro-Pro-Gly)10, a synthetic polypeptide model of collagen

1972 • 72 citations

A synthetic model of collagen: An experimental investigation of the triple‐helix stability

1988 • 60 citations

NMR and CD studies of triple‐helical peptides

1992 • 58 citations

Collagen Genes: Mutations Affecting Collagen Structure and Expression

1994 • 56 citations

Hydroxylation of (X-Pro-Gly)n by protocollagen proline hydroxylase Effect of chain length, helical conformation and amino acid sequence in the substrate

1972 • 54 citations

Triple helix–coil transition of covalently bridged collagenlike peptides

1980 • 50 citations

Structure Analysis of a Collagen Model Polypeptide, (Pro–Pro–Gly)₁₀

1976 • 49 citations

Influence of different tripeptides on the stability of the collagen triple helix. II. An experimental approach with appropriate variations of a trimer model oligotripeptide

1986 • 47 citations

Inter-chain Proline: Proline Contacts Contribute to the Stability of the Triple Helical Conformation

1988 • 47 citations

Purification and Analysis of Synthetic, Triple-Helical "Minicollagens" by Reversed-Phase High-Performance Liquid Chromatography

1995 • 46 citations

Infrared spectra and structure of synthetic polytripeptides

1978 • 45 citations

Titration and Melting Curves of the Collagen-like Triple Helices Formed from (Pro-Pro-Gly)10 in Aqueous Solution

1970 • 44 citations

A model for the triple-helical structure of (Pro-Hyp-Gly)10 involving a cis peptide bond and inter-chain hydrogen-bonding to the hydroxyl group of hydroxyproline

1973 • 37 citations

The synthetic polytripeptides (Pro-Pro-Gly)10 and (Pro-Pro-Gly)20 form micro-crystalline structures similar to segmental structures formed by collagen

1971 • 35 citations

A synthetic model of collagen structure taken from bovine macrophage scavenger receptor

1993 • 33 citations

The enzymic hydroxylation of protocollagen models

1969 • 31 citations

Nuclear magnetic resonance and circular dichroism studies of a triple-helical peptide with a glycine substitution

1992 • 28 citations

Promotion of human platelet adhesion and aggregation by a synthetic, triple-helical “mini-collagen”.

1994 • 27 citations

The association reaction of collagen model polypeptides (Pro‐Pro‐Gly)_n

1975 • 26 citations

Synthetic Polypeptide Models of Collagen: Synthesis and Applications

1976 • 25 citations

Die Struktur kollagenähnlicher Homo‐ und Heteropolytripeptide, 4. Polytripeptide durch repetitive Peptidsynthese und Verbrückung von Oligopeptiden

1979 • 20 citations

Solution‐phase Raman‐spectroscopic studies on synthetic collagen analogs: Prolyl‐prolyl‐glycine and (prolyl‐prolyl‐glycine)₁₀

1984 • 18 citations

Evidence for a Triple Helix Recognition Site in the Hemopexin‐like Domains of Human Fibroblast and Neutrophil Interstitial Collagenases^a

1994 • 18 citations

Low-frequency Raman spectra as a conformational probe for polypeptides and proteins

1985 • 15 citations

Conformational change of the triple‐helical structure. II. Conformation of (Pro‐Pro‐Gly)_n and (Pro‐Pro‐Gly)_n(Ala‐Pro‐Gly)_m(Pro‐Pro‐Gly)_n in an aqueous solution

1974 • 15 citations

¹³C nuclear magnetic resonance study of the triple helix ⇌ random‐coil transition of (prolylprolyglycyl)₁₀

1979 • 12 citations

Conformational change of the triple‐helical structure. I. Synthesis of model peptides of collagen by the solid‐phase method

1974 • 11 citations

Der Einfluss der O‐Acetylierung auf das konformative Verhalten des Kollagen‐Modellpeptides (<scp>L</scp>‐Pro‐<scp>L</scp>‐Hyp‐Gly)₁₀ und von Gelatine

1978 • 9 citations