Synthetic Polypeptide Models of Collagen: Synthesis and Applications

Solid Phase Peptide Synthesis. I. The Synthesis of a Tetrapeptide

1963 • 7,266 citations

Solid Phase Peptide Synthesis

1976 • 1,798 citations

The Use of Esters of N-Hydroxysuccinimide in Peptide Synthesis

1964 • 1,214 citations

Ann Arbor, Michigan

1969 • 1,061 citations

The Chemistry and Structure of Collagen

1971 • 555 citations

Solid-Phase Peptide Synthesis. III. An Improved Synthesis of Bradykinin^*

1964 • 555 citations

Analysis of the primary structure of collagen for the origins of molecular packing

1973 • 413 citations

Conformational Properties of Macromolecules

1973 • 322 citations

Evidence for the Linkage of a Disaccharide to Hydroxylysine in Tropocollagen

1966 • 298 citations

Synthesis of (Pro-Hyp-Gly)n of defined molecular weights Evidence for the stabilization of collagen triple helix by hydroxypyroline

1973 • 291 citations

Characterization and Quantitative Determination of the Hydroxylysine-linked Carbohydrate Units of Several Collagens

1969 • 289 citations

Total synthesis of an enzyme with ribonuclease A activity

1969 • 278 citations

Conformational energies and configurational statistics of copolypeptides containing l-proline

1968 • 241 citations

Role of pyrrolidine residues in the structure and stabilization of collagen

1964 • 240 citations

Helix [UNK] Coil Transitions in Dilute Aqueous Collagen Solutions¹

1960 • 223 citations

Carboxyl-catalyzed intramolecular aminolysis. Side reaction in solid-phase peptide synthesis

1972 • 215 citations

A hypothesis on the role of hydroxyproline in stabilizing collagen structure

1973 • 186 citations

Hydroxylation of Proline in Synthetic Polypeptides with Purified Protocollagen Hydroxylase

1967 • 167 citations

Synthesis of Angiotensins by the Solid-Phase Method^*

1965 • 165 citations

Computation of the sterically allowed conformations of peptides

1966 • 155 citations

Polymers of tripeptides as collagen models

1966 • 152 citations

Comparative Sequence Studies of Rat Skin and Tendon Collagen. I. Evidence for Incomplete Hydroxylation of Individual Prolyl Residues in the Normal Proteins^*

1967 • 149 citations

Synthesis of Poly-(<scp>l</scp>-prolyl-<scp>l</scp>-prolylglycyl) of Defined Molecular Weights

1968 • 148 citations

Peptide Syntheses Via Amino Acid Active Esters¹

1959 • 147 citations

Structure of α1-CB8, a large cyanogen bromide produced fragment from the α1 chain of rat collagen. The nature of a hydroxylamine-sensitive bond and composition of tryptic peptides

1970 • 146 citations

STUDIES ON THE CONFORMATION OF AMINO ACIDS

1971 • 143 citations

Studies on the structure of poly-l-proline in solution

1958 • 135 citations

Purification of carbon-14-labeled protocollagen and its hydroxylation by prolyl-hydroxylase

1973 • 120 citations

Physicochemical analysis of (Pro‐Pro‐Gly)_n with defined molecular weight–temperature dependence of molecular weight in aqueous solution

1970 • 114 citations

Tetraethyl Pyrophosphite as a Reagent for Peptide Syntheses¹

1952 • 113 citations

Synthesis and structural studies of two collagen analogues: Poly (l-prolyl-l-seryl-glycyl) and poly (l-prolyl-l-alanyl-glycyl)

1972 • 112 citations

Failure sequences in the solid phase synthesis of polypeptides

1970 • 111 citations

Synthese von Polypeptiden. XV

1906 • 97 citations

Polypeptides with Known Repeating Sequence of Amino Acids. Synthesis of Poly-L-glutamyl-L-alanyl-L-glutamic Acid and Polyglycylglycyl-L-phenylalanine through Pentachlorophenyl Active Ester¹

1966 • 96 citations

Polymers of tripeptides as collagen models

1966 • 96 citations

Enzymic studies of the gelatin → collagen-fold transition

1959 • 96 citations

The Constitution of Gelatin. Separation and Estimation of Peptides in Partial Hydrolysates

1954 • 96 citations

The Covalent Structure of Collagen

1972 • 92 citations

COMPLEX SALTS OF AMINO ACIDS AND PEPTIDES

1935 • 91 citations

Isolation and characterization of the peptides derived from the α1 chain of chick bone collagen after cyanogen bromide cleavage

1969 • 90 citations

The Introduction of Intramolecular Covalent Cross-linkages into Ichthyocol Tropocollagen with Monofunctional Aldehydes

1963 • 85 citations

Structure of rat skin collagen α1-CB8. Amino acid sequence of the hydroxylamine-produced fragment HA1

1971 • 83 citations

Investigation of the denaturation and renaturation of soluble collagen by light scattering

1962 • 83 citations

Protocollagen lysine hydroxylase. Hydroxylation of synthetic peptides and the stoichiometric decarboxylation of α-ketoglutarate

1972 • 83 citations

Isolation and characterization of the peptides derived from the α2 chain of chick bone collagen after cyanogen bromide cleavage

1969 • 81 citations

Molecular mobility of polypeptides containing proline as determined by ¹³C magnetic resonance

1974 • 81 citations

Chemical studies on the cyanogen bromide peptides of rat skin collagen. Covalent structure of α1-CB5, the major hexose-containing cyanogen bromide peptide of α1

1970 • 80 citations

Reactions of Carbodiimides. III. The Reactions of Carbodiimides with Peptide Acids^1,2

1966 • 77 citations

Synthetic polypeptides as substrates and inhibitors of collagen proline hydroxylase

1968 • 75 citations

Characterization of the cyanogen bromide peptides from the α1 chain of chick skin collagen

1969 • 70 citations

Importances of Polar Groups for initiating Blood Coagulation and aggregating Platelets

1969 • 70 citations

Chemical studies on the cyanogen bromide peptides of rat skin collagen. Amino acid sequence of α1-CB4

1971 • 67 citations

The Covalent Structure of Collagen

1973 • 65 citations

Low temperature circular dichroism of poly (glycyl-l-prolyl-l-alanine)

1969 • 65 citations

Direct evidence for a correlation between amino acid sequence and cross striation pattern of collagen

1970 • 63 citations

Peptides: Chemistry and biochemistry

1971 • 63 citations

Polymers of tripeptides as collagen models

1969 • 61 citations

Comparative sequence studies of rat skin and tendon collagen. II. Absence of a short sequence at the amino terminus of the skin α1 chain

1969 • 61 citations

Formation of Enzyme-Substrate Complexes with Protocollagen Proline Hydroxylase and Large Polypeptide Substrates

1969 • 59 citations

Peptides Isolated from a Partial Hydrolysate of Steer Hide Collagen. II. Evidence for the Prolyl-Hydroxyproline Linkage in Collagen

1955 • 57 citations

The Covalent Structure of Collagen

1972 • 56 citations

Polymers of tripeptides as collagen models

1969 • 56 citations

Hydroxylation of (X-Pro-Gly)n by protocollagen proline hydroxylase Effect of chain length, helical conformation and amino acid sequence in the substrate

1972 • 54 citations

Conformational investigations on the polypeptide and oligopeptides with the repeating sequence L-alanyl-L-prolylglycine

1971 • 53 citations

Synthesis of Peptide Polymers with Repeating Sequences

1963 • 51 citations

Polyamino Acids as Protein Models

1964 • 49 citations

On the Structure of Gly-Pro-Gly and Gly-Pro-Ala Oligopeptides and Sequential Polypeptides^1-3

1966 • 47 citations

Some Stereochemical Implications of the Molecular Conformation of Collagen

1974 • 47 citations

X-RAY STUDIES OF PROTEIN STRUCTURE

1934 • 46 citations

Interactions between mucopolysaccharides and cationic polypeptides in aqueous solution: Chondroitin 4‐sulfate and dermatan sulfate

1973 • 46 citations

Peptide Synthesis via Amino Acid Active Esters. II.¹ Some Abnormal Reactions during Peptide Synthesis

1962 • 46 citations

Glycine Analogs of Bradykinin

1963 • 45 citations

Titration and Melting Curves of the Collagen-like Triple Helices Formed from (Pro-Pro-Gly)10 in Aqueous Solution

1970 • 44 citations

Piperazinedione formation from esters of dipeptides containing glycine, alanine, and sarcosine: the kinetics in aqueous solution

1973 • 43 citations

Structure of rat skin collagen α1-CB8. Amino acid sequence of the hydroxylamine-produced fragment HA2

1972 • 42 citations

Interactions between chondroitin‐6‐sulfate and poly‐<scp>L</scp>‐lysine in aqueous solution: Circular dichroism studies

1973 • 42 citations

Oligopeptides with the Sequences Ala-Pro-Gly and Gly-Pro-Gly as Substrates or Inhibitors for Protocollagen Proline Hydroxylase

1969 • 40 citations

Effect of Polymer Size on the Inhibition of Protocollagen Proline Hydroxylase by Polyproline II

1969 • 39 citations

THYMUS INDEPENDENCE OF A COLLAGEN-LIKE SYNTHETIC POLYPEPTIDE AND OF COLLAGEN, AND THE NEED FOR THYMUS AND BONE MARROW-CELL COOPERATION IN THE IMMUNE RESPONSE TO GELATIN

1974 • 38 citations

The Synthesis of Glycyl-L-prolylglycyl and Glycyl-L-prolyl-L-alanyl Oligopeptides and Sequential Polypeptides¹

1966 • 37 citations

PEPTIDE SYNTHESIS VIA OXIDATION OF HYDRAZIDES

1961 • 36 citations

Synthesis, Structure, and Biological Properties of Sequential Polypeptides

1974 • 35 citations

Immunological properties of a collagen-like synthetic polypeptide

1969 • 35 citations

Synthesis of Poly-(L-prolyl-L-leucyl-glycyl). An Attempted Synthesis of Model Collagen

1958 • 34 citations

The synthesis and polymerization of peptide p-nitrophenyl esters

1965 • 34 citations

Chromatographic Separation and Identification of Some Peptides in Partial Hydrolysates of Gelatin

1953 • 32 citations

The enzymic hydroxylation of protocollagen models

1969 • 31 citations

Synthese von Polypeptiden. XV

1923 • 31 citations

Peptides Isolated from a Partial Hydrolysate of Steer Hide Collagen

1953 • 29 citations

Immunological cross-reactions between the synthetic ordered polypeptide (L-Pro-Gly-L-Pro)n and several collagens

1973 • 28 citations

Synthese von Peptiden

1956 • 27 citations

Polypeptide models of collagen. Solution properties of (Gly‐Pro‐Sar)_n and (Gly‐Sar‐Pro)_n

1976 • 25 citations

The Poly(hydroxy-L-proline) Ring Conformation Determined by Proton Magnetic Resonance

1972 • 24 citations

Synthesis of polypeptides and oligopeptides with the repeating sequence L-alanyl-L-prolylglycine

1971 • 24 citations

Synthesis of polydepsipeptides with regularly repeating unit sequences

1969 • 23 citations

Peptide Synthesis: A Review of the Solid-Phase Method

1973 • 22 citations

[A synthetic polymer isomorphous with collagen].

1961 • 22 citations

Development of ordered structures in sequential copolypeptides containing L-proline and γ-hydroxy-L-proline

1971 • 21 citations

Immune response to the collagen-like synthetic ordered polypeptide (L-Pro-Gly-L-Pro)n

1973 • 18 citations

Copolymers of <scp>L</scp>‐proline and sarcosine: Synthesis and physical‐chemical studies

1963 • 18 citations

SYNTHESIS OF POLYPEPTIDE MODELS OF COLLAGEN

1975 • 18 citations

Polypeptide models of collagen: Properties of (Pro‐Pro‐βAla)_n

1975 • 17 citations

Comparison of Poly-L-proline I and II äs Inhibitors of Protocollagen Hydroxylase

1967 • 17 citations

Sequential polypeptides. Part VI. The synthesis of some sequential polypeptide collagen models containing proline analogues

1972 • 17 citations

Synthesis of Sequence Peptide Polymers Related to Collagen.

1972 • 17 citations

Asymmetry in the hydroxylation of (Pro-Pro-Gly)5 by protocollagen proline hydroxylase

1971 • 17 citations

Synthetic Polypeptides as Models for Collagen

1968 • 16 citations

A cooperative transition between two helical conformations in a linear system: poly‐<scp>L</scp>‐proline I ⇌ II. II. Kinetic studies

1971 • 16 citations

Hydroxylation of proline in collagen model peptide

1969 • 15 citations

The synthesis and immunological activity of a peptide related to collagen

1967 • 15 citations

Racemization in the synthesis of polytripeptide models of collagen

1976 • 14 citations

COMPLEX SALTS OF AMINO ACIDS AND PEPTIDES

1938 • 14 citations

Sequential polypeptides. Part V. The use of monoesters of catechol in the synthesis of sequential polypeptides with amino- or carboxy-side-chains

1972 • 13 citations

Sequential polypeptides. Part I. Use of mono-esters of catechol in the synthesis of sequential polypeptides

1971 • 12 citations

CYCLOLS‐FORMATION FROM TRIPEPTIDE SYSTEMS AND STRUCTURE ASSIGNMENT BY CARBON‐13 NUCLEAR MAGNETIC RESONANCE

1973 • 11 citations

The synthesis of an enzyme.

1969 • 10 citations

POLYPEPTIDE MODELS OF COLLAGEN: SYNTHESIS OF (PRO‐PRO‐ALA)_n AND (PRO‐PRO‐VAL)_n

1976 • 10 citations

Synthesis and enzymic hydroxylation of protocollagen model peptide containing a hydroxyproline residue

1971 • 8 citations

Structural and Morphological Investigation of Poly (Gly-Ala-Pro)

1970 • 8 citations

Syntheses and enzymic hydroxylation of protocollagen model peptides containing glutamyl or leucyl residue

1972 • 8 citations

The antigenicity of sequential polypeptides. I. The synthesis of some sequential collagen models.

1973 • 7 citations

SEQUENTIAL POLYPEPTIDES.

1975 • 7 citations

Synthetische Polypeptide der Sequenztypen (Glycin-L-Prolin-L-Serin)_n und (Glycin-L-Serin-L-Prolin) / Synthetic polypeptides of the sequences (glycine-L-proline-L-serine) _n and (glycine-L-serine-L-proline) _n

1969 • 7 citations

Recent Trends in the Synthesis of Linear Peptides

1970 • 7 citations

POLYPEPTIDE MODELS OF COLLAGEN. SYNTHESIS OF (PRO‐PRO‐β‐ALA)_n

1975 • 6 citations

[Synthesis of high-molecular polytripeptide (-Gly-Pro-Pro-)n with collagen-type structure].

1971 • 5 citations

The use of mono-esters of catechol in the racemisation-free synthesis of sequential polypeptides with amino or carboxy side-chains

1971 • 5 citations

The structure and stabilization of the collagen macromolecule.

1960 • 5 citations

[Synthesis of protected oligopeptides with the sequence--Gly-Pro-Pro--and occurrence among them of collagen-type structures].

1971 • 4 citations

Racemization in the synthesis of sequential polypeptides using N‐hydroxysuccinimide esters

1976 • 4 citations

2,4,5-trichlorophenyl esters and their use in synthesis of polypeptides of regular structure

1969 • 3 citations

Synthesis of polypeptides of regular structure, containing serine and glutamic acid, and modeling the nonpolar regions of the collagen protein molecule

1970 • 3 citations

Synthesis of certain polydipeptides and polytripeptides

1968 • 3 citations

Synthesis of regular polypeptides with a collagen type of sequence: -gly-glu(och3)-pro- and -pro-his(cbo)-gly-

1973 • 1 citations

コラーゲンの生合前駆体モデルペプチド中のプロリンの水酸化, Suzuki, F., Koyama, E., Biochim. Biophys. Acta 177,154,1969

1969 • 1 citations

Deleted Work

1955 • 0 citations