Transcripts of the insulin-like growth factors I and II in human hepatoma.

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

Purification of Biologically Active Globin Messenger RNA by Chromatography on Oligothymidylic acid-Cellulose

1972 • 6,922 citations

A general method for isolation of high molecular weight DNA from eukaryotes

1976 • 2,827 citations

Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences

1984 • 2,564 citations

Ribonucleic acid isolated by cesium chloride centrifugation

1974 • 2,263 citations

Human Hepatocellular Carcinoma Cell Lines Secrete the Major Plasma Proteins and Hepatitis B Surface Antigen

1980 • 2,034 citations

Isolation and characterization of rat and human glyceraldehyde-3-phosphate dehydrogenase cDNAs: genomic complexity and molecular evolution of the gene

1985 • 1,836 citations

Platelet-derived growth factor is structurally related to the putative transforming protein p28sis of simian sarcoma virus

1983 • 1,657 citations

The c-fms proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF 1

1985 • 1,590 citations

Growth hormone receptor and serum binding protein: purification, cloning and expression

1987 • 1,540 citations

The amino acid sequence of human insulin-like growth factor I and its structural homology with proinsulin.

1978 • 1,530 citations

Autocrine growth factors and cancer

1985 • 1,462 citations

Growth of human hepatoma cells lines with differentiated functions in chemically defined medium.

1982 • 1,367 citations

Controlled synthesis of HBsAg in a differentiated human liver carcinoma-derived cell line

1979 • 1,305 citations

Evolutionary conservation in the untranslated regions of actin mRNAs: DNA sequence of a human beta-actin cDNA

1984 • 973 citations

Alpha-Fetoprotein in Ontogenesis and its Association with Malignant Tumors

1971 • 892 citations

Amine synthesis in rapidly growing tissues: ornithine decarboxylase activity in regenerating rat liver, chick embryo, and various tumors.

1968 • 742 citations

Insulin-like growth factor I stimulates growth in hypophysectomized rats

1982 • 605 citations

Somatomedin-C/insulin-like growth factor-I and insulin-like growth factor-II mRNAs in rat fetal and adult tissues.

1986 • 531 citations

Gene amplification causes overproduction of the first three enzymes of UMP synthesis in N-(phosphonacetyl)-L-aspartate-resistant hamster cells.

1979 • 484 citations

Insulin-like growth factor-II gene expression in Wilms' tumour and embryonic tissues

1985 • 413 citations

Sequence of cDNA encoding human insulin-like growth factor I precursor

1983 • 401 citations

Organization and sequence of the human insulin-like growth factor I gene. Alternative RNA processing produces two insulin-like growth factor I precursor peptides.

1986 • 371 citations

Expression of insulin-like growth factor-II transcripts in Wilms' tumour

1985 • 352 citations

Hepatitis B surface antigen produced by a human hepatoma cell line

1976 • 323 citations

Increased levels of multiplication-stimulating activity, an insulin-like growth factor, in fetal rat serum.

1980 • 313 citations

6 Factors controlling blood concentration of somatomedin C

1984 • 299 citations

Enhanced levels of insulin-like growth factor messenger RNA in human colon carcinomas and liposarcomas.

1986 • 293 citations

Developmental patterns of insulin-like growth factor-I and -II synthesis and regulation in rat fibroblasts

1983 • 269 citations

Human chromosomal mapping of genes for insulin-like growth factors I and II and epidermal growth factor

1984 • 267 citations

Two insulin-like growth factor I messenger RNAs are expressed in human liver.

1986 • 260 citations

Primary structures of human alpha-fetoprotein and its mRNA.

1983 • 259 citations

Isolation of the human insulin-like growth factor genes: insulin-like growth factor II and insulin genes are contiguous.

1985 • 212 citations

Insulin-like growth factor II in human adrenal pheochromocytomas and Wilms tumors: expression at the mRNA and protein level.

1987 • 191 citations

Localization of insulin-like growth factor genes to human chromosomes 11 and 12

1984 • 180 citations

The human insulin‐like growth factor II gene contains two development‐specific promoters

1987 • 170 citations

Nucleotide sequences of cDNAs encoding precursors of human insulin‐like growth factor II (IGF‐II) and an IGF‐II variant

1985 • 164 citations

Isolation of high-molecular-weight DNA from insects

1990 • 139 citations

Hypoglycemia Associated with Non-Islet-Cell Tumor and Insulin-like Growth Factors

1981 • 136 citations

α‐Fetoprotein as a Marker of Embryo‐Specific Differentiations in Normal and Tumor Tissues

1974 • 121 citations

Complete Amino Acid Sequence of Human Ornithine Decarboxylase Deduced from Complementary DNA

1987 • 99 citations

5 Somatomedin levels in childhood, adolescence and adult life

1984 • 92 citations

Evidence for an increased somatomedin-C/insulin-like growth factor I content in primary human lung tumors

1987 • 89 citations

Alpha‐fetoprotein: Immunochemical Purification and Chemical Properties. Expression in Normal State and in Malignant and non‐Malignant Liver Disease

1974 • 76 citations

Structure of two unlinked Drosophila melanogaster glyceraldehyde-3-phosphate dehydrogenase genes.

1985 • 67 citations

Radioimmunoassay of serum IGF-I and IGF-II in patients with chronic liver diseases and hepatocellular carcinoma with or without hypoglycemia.

1988 • 67 citations

Serum Levels of Immunoreactive Somatomedin A in the Rat: Some Developmental Aspects*

1980 • 53 citations

In Vitro Regulation of Ornithine Decarboxylase in Dog Thyroid Slices*

1980 • 24 citations