Mapping myosin light chains by immunoelectron microscopy. Use of anti-fluorescyl antibodies as structural probes.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Regulation and Kinetics of the Actin-Myosin-ATP Interaction

1980 • 1,077 citations

Substructure of the myosin molecule

1971 • 1,062 citations

Three-dimensional structure of calmodulin

1985 • 1,035 citations

[7] Preparation of myosin and its subfragments from rabbit skeletal muscle

1982 • 963 citations

An electrophoretic study of the low-molecular-weight components of myosin

1970 • 706 citations

Structure of the calcium regulatory muscle protein troponin-C at 2.8 Å resolution

1985 • 619 citations

Electron microscopy of an antibody-hapten complex

1967 • 505 citations

Light Chains from Fast and Slow Muscle Myosins

1971 • 474 citations

Physicochemical properties of rat testis Ca2+-dependent regulator protein of cyclic nucleotide phosphodiesterase. Relationship of Ca2+-binding, conformational changes, and phosphodiesterase activity

1977 • 459 citations

Synthesis and characterization of two fluorescent sulfhydryl reagents

1973 • 431 citations

Rotary shadowing of extended molecules dried from glycerol

1980 • 420 citations

Molecular Structure of Troponin C from Chicken Skeletal Muscle at 3-Angstrom Resolution

1985 • 342 citations

Shape and flexibility of the myosin molecule

1978 • 329 citations

Comparison of the crystal and solution structures of calmodulin and troponin C

1988 • 322 citations

A phosphorylated light-chain component of myosin from skeletal muscle

1973 • 301 citations

Studies on the role of myosin alkali light chains

1977 • 300 citations

The light chains of scallop myosin as regulatory subunits

1973 • 294 citations

Reversible phosphorylation of smooth muscle myosin, heavy meromyosin, and platelet myosin.

1981 • 259 citations

Crossbridge behaviour during muscle contraction

1985 • 249 citations

The central helix of calmodulin functions as a flexible tether.

1988 • 245 citations

Cyanylation of sulfhydryl groups by 2-nitro-5-thiocyanobenzoic acid. High-yield modification and cleavage of peptides at cysteine residues

1974 • 240 citations

Hydrolysis of ATP and reversible binding to F-actin by myosin heavy chains free of all light chains

1981 • 185 citations

Changes in the X-ray reflections from contracting muscle during rapid mechanical transients and their structural implications

1983 • 182 citations

Monoclonal antibodies localize changes on myosin heavy chain isozymes during avian myogenesis

1983 • 177 citations

Structural homology of myosin alkali light chains, troponin C and carp calcium binding protein

1974 • 171 citations

Homology of myosin DTNB light chain with alkali light chains, troponin C and parvalbumin

1976 • 155 citations

The free heavy chain of vertebrate skeletal myosin subfragment 1 shows full enzymatic activity.

1982 • 145 citations

Calcium-induced increase in the radius of gyration and maximum dimension of calmodulin measured by small-angle x-ray scattering

1985 • 135 citations

Electron microscopy of scallop myosin

1983 • 132 citations

[55] Special instrumentation and techniques for kinetic studies of contractile systems

1982 • 126 citations

On the origin of the contractile force in skeletal muscle.

1979 • 122 citations

Mechanisms of ligand binding by monoclonal anti-fluorescyl antibodies.

1982 • 115 citations

Probing myosin head structure with monoclonal antibodies

1986 • 101 citations

Domains, motions and regulation in the myosin head

1988 • 97 citations

Interaction of skeletal myosin light chains with calcium ions

1978 • 95 citations

Relation of structure to function in myosin. II. Salt denaturation and recombination experiments

1970 • 89 citations

Fluorescein. Hapten and antibody active-site probe

1971 • 89 citations

Movement of myosin fragments in vitro: Domains involved in force production

1987 • 89 citations

Fluorescence energy transfer in myosin subfragment-1

1980 • 88 citations

Stabilization of the long central helix of troponin C by intrahelical salt bridges between charged amino acid side chains.

1985 • 80 citations

Immunological approach to the role of the low-molecular-weight subunits in myosin. I. Physical-chemical and immunological characterization of the light chains

1975 • 78 citations

Light-chain movement and regulation in scallop myosin

1983 • 73 citations

The light chains of muscle myosin: Its structure, function, and evolution

1983 • 72 citations

Location of the ATPase site of myosin determined by three-dimensional electron microscopy

1987 • 68 citations

Structural and immunological characterization of the myosin-like 110-kD subunit of the intestinal microvillar 110K-calmodulin complex: evidence for discrete myosin head and calmodulin-binding domains.

1988 • 64 citations

Physical characterization of myosin light chains

1978 • 64 citations

Formation and characterization of myosin hybrids containing essential light chains and heavy chains from different muscle myosins.

1981 • 61 citations

Recombinant DNA approach for defining the primary structure of monoclonal antibody epitopes

1985 • 57 citations

The widespread distribution of α‐N‐trimethylalanine as the N‐terminal amino acid of light chains from vertebrate striated muscle myosins

1985 • 56 citations

Isolation and distribution of myosin isoenzymes in chicken pectoralis muscle

1981 • 55 citations

Small-angle x-ray scattering investigation of the solution structure of troponin C.

1988 • 52 citations

Myosin subunit interactions. Localization of the alkali light chains.

1985 • 48 citations

Crystallization of myosin subfragment 1.

1984 • 44 citations

The essential light chains constitute part of the active site of smooth muscle myosin

1986 • 43 citations

Regulatory and essential light-chain interactions in scallop myosin

1982 • 41 citations

Muscle Cross-Bridges: Do They Rotate?

1984 • 41 citations

Visualization of domains in native and nucleotide-trapped myosin heads by negative staining

1988 • 39 citations

Position of the amino terminus of myosin light chain 1 and light chain 2 determined by electron microscopy with monoclonal antibody

1987 • 38 citations

Domain structure of the myosin head in correlation-averaged images of shadowed molecules

1988 • 22 citations

Location of the SH group of the alkali light chain on the myosin head as revealed by electron microscopy

1985 • 20 citations

Dissociation and reassociation of rabbit skeletal muscle myosin

1980 • 19 citations

Cross-linking between translationally equivalent sites on the two heads of myosin. Relationship to energy transfer results between the same pair of sites.

1988 • 17 citations

Structural Models for the Regulatory Switch of Myosin

1986 • 15 citations

Ca2+-Induced Confonnational Changes of 20,000 Dalton Light Chain of Vertebrate Striated Muscle Myosins1

1983 • 11 citations