Polymorphism and Divergence at a Drosophila Pseudogene Locus

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

1988 • 17,059 citations

The Neutral Theory of Molecular Evolution

1979 • 7,965 citations

Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase

1988 • 4,259 citations

On the number of segregating sites in genetical models without recombination

1975 • 3,989 citations

The hitch-hiking effect of a favourable gene

2007 • 2,840 citations

The effect of deleterious mutations on neutral molecular variation.

1993 • 1,838 citations

A Test of Neutral Molecular Evolution Based on Nucleotide Data

1987 • 1,789 citations

Drosophila: A laboratory handbook

1990 • 1,742 citations

The neutral theory of molecular evolution

1984 • 1,459 citations

DNA POLYMORPHISM DETECTABLE BY RESTRICTION ENDONUCLEASES

1981 • 1,346 citations

Drosophila: A laboratory handbook

1990 • 1,243 citations

The "hitchhiking effect" revisited.

1989 • 1,137 citations

Levels of naturally occurring DNA polymorphism correlate with recombination rates in D. melanogaster

1992 • 987 citations

An evolutionary perspective on synonymous codon usage in unicellular organisms

1986 • 874 citations

Synonymous codon usage in Drosophila melanogaster: natural selection and translational accuracy.

1994 • 747 citations

Inferring weak selection from patterns of polymorphism and divergence at "silent" sites in Drosophila DNA.

1995 • 554 citations

Pseudogenes as a paradigm of neutral evolution

1981 • 526 citations

Simultaneous editing of multiple nucleic acid and protein sequences with ESEE

1989 • 492 citations

Deleterious background selection with recombination.

1995 • 467 citations

Patterns of nucleotide substitution in pseudogenes and functional genes

1982 • 460 citations

Cloning of DNA sequences from the white locus of D. melanogaster by a novel and general method

1981 • 446 citations

Intraspecific nuclear DNA variation in Drosophila

1996 • 425 citations

High intrinsic rate of DNA loss in Drosophila

1996 • 385 citations

The effect of background selection against deleterious mutations on weakly selected, linked variants

1994 • 376 citations

Production of single-stranded DNA templates by exonuclease digestion following the polymerase chain reaction

1989 • 342 citations

The effect of strongly selected substitutions on neutral polymorphism: Analytical results based on diffusion theory

1992 • 342 citations

Models of nearly neutral mutations with particular implications for nonrandom usage of synonymous codons

1987 • 271 citations

Background selection and patterns of genetic diversity inDrosophila melanogaster

1996 • 265 citations

Lack of polymorphism on the Drosophila fourth chromosome resulting from selection.

1991 • 257 citations

DnaSP version 2.0: a novel software package for extensive molecular population genetics analysis.

1997 • 248 citations

Cuticle protein genes of Drosophila: Structure, organization and evolution of four clustered genes

1982 • 226 citations

Analysis of a genetic hitchhiking model, and its application to DNA polymorphism data from Drosophila melanogaster.

1993 • 212 citations

Natural Selection and the Frequency Distributions of “Silent” DNA Polymorphism in Drosophila

1997 • 179 citations

Polymorphism and divergence in the Mst26A male accessory gland gene region in Drosophila.

1992 • 170 citations

The size distribution of insertions and deletions in human and rodent pseudogenes suggests the logarithmic gap penalty for sequence alignment

1995 • 162 citations

Theoretical Statistics.

1975 • 151 citations

Deletions in processed pseudogenes accumulate faster in rodents than in humans

1989 • 141 citations

Are codon usage patterns in unicellular organisms determined by selection‐mutation balance?

1988 • 129 citations

Evolution of the 87A and 87C heat-shock loci in Drosophila

1981 • 127 citations

Evolutionary rates of insertion and deletion in noncoding nucleotide sequences of primates.

1994 • 111 citations

Evidence for adaptive evolution of the G6pd gene in the Drosophila melanogaster and Drosophila simulans lineages.

1993 • 108 citations

Extraordinarily high evolutionary rate of pseudogenes: evidence for the presence of selective pressure against changes between synonymous codons.

1981 • 102 citations

USING HITCHHIKING GENES TO STUDY ADAPTATION AND DIVERGENCE DURING SPECIATION WITHIN THE DROSOPHILA MELANOGASTER SPECIES COMPLEX

1994 • 93 citations

Evolutionary inferences from DNA variation at the 6-phosphogluconate dehydrogenase locus in natural populations of drosophila: selection and geographic differentiation.

1994 • 86 citations

Molecular variation at the vermilion locus in geographically diverse populations of Drosophila melanogaster and D. simulans.

1995 • 79 citations

ESTIMATING GENETIC VARIABILITY WITH RESTRICTION ENDONUCLEASES

1982 • 76 citations

Lack of correlation between interspecific divergence and intraspecific polymorphism at the suppressor of forked region in Drosophila melanogaster and Drosophila simulans.

1993 • 69 citations

Molecular population genetics of ref(2)P, a locus which confers viral resistance in Drosophila

1996 • 68 citations

Multi-Locus Selection and the Structure of Variation at the white Gene of Drosophila melanogaster

1996 • 64 citations

Intraspecific and interspecific variation at the y-ac-sc region of Drosophila simulans and Drosophila melanogaster.

1992 • 60 citations

Molecular evolution of Drosophila metallothionein genes.

1990 • 53 citations

Variation at the 87A heat shock locus in Drosophila melanogaster

1983 • 49 citations

Causes and consequences of variation in energy storage in Drosophila melanogaster.

1989 • 46 citations

Evolutionary relationships and sequence variation of alpha-amylase variants encoded by duplicated genes in the Amy locus of Drosophila melanogaster.

1995 • 42 citations

Using Hitchhiking Genes to Study Adaptation and Divergence During Speciation Within the Drosophila melanogaster Species Complex

1994 • 41 citations

Nucleotide variation at the hypervariable esterase 6 isozyme locus of Drosophila simulans.

1995 • 41 citations

Molecular evolution of the Rh3 gene in Drosophila

1993 • 24 citations

Neutral mutation hypothesis test

1991 • 21 citations

Polymorphism and divergence at the prune locus in Drosophila melanogaster and D. simulans.

1994 • 20 citations

Molecular Evolution at the decapentaplegic Locus in Drosophila

1997 • 17 citations

Reduced variation atconcertina, a heterochromatic locus inDrosophila

1996 • 13 citations

Analysis of DNA structural patterns and sequence organization at the larval cuticle locus in Drosophila melanogaster.

1983 • 6 citations