The effect of background selection against deleterious mutations on weakly selected, linked variants

Statistical method for testing the neutral mutation hypothesis by DNA polymorphism.

1989 • 13,216 citations

The Neutral Theory of Molecular Evolution

1983 • 6,141 citations

The Genetics and Biology of Drosophila

1978 • 3,910 citations

Adaptive protein evolution at the Adh locus in Drosophila

1991 • 3,323 citations

The hitch-hiking effect of a favourable gene

1974 • 3,276 citations

The Genome of Drosophila Melanogaster

1992 • 3,126 citations

The hitch-hiking effect of a favourable gene

2007 • 2,840 citations

The effect of deleterious mutations on neutral molecular variation.

1993 • 1,838 citations

A Test of Neutral Molecular Evolution Based on Nucleotide Data

1987 • 1,789 citations

Fundamentals of molecular evolution

1991 • 1,721 citations

Proceedings of the National Academy of Sciences

2024 • 1,483 citations

The causes of molecular evolution

1992 • 1,307 citations

Drosophila: A laboratory handbook

1990 • 1,243 citations

ON THE PROBABILITY OF FIXATION OF MUTANT GENES IN A POPULATION

1962 • 1,195 citations

The "hitchhiking effect" revisited.

1989 • 1,137 citations

Deleterious mutations and the evolution of sexual reproduction

1988 • 1,130 citations

The Relative Rates of Evolution of Sex Chromosomes and Autosomes

1987 • 1,072 citations

MOLECULAR BIOLOGY AND EVOLUTION

2012 • 1,060 citations

The Nearly Neutral Theory of Molecular Evolution

1992 • 1,052 citations

The selection-mutation-drift theory of synonymous codon usage.

1991 • 994 citations

Levels of naturally occurring DNA polymorphism correlate with recombination rates in D. melanogaster

1992 • 987 citations

THE NUMBER OF HETEROZYGOUS NUCLEOTIDE SITES MAINTAINED IN A FINITE POPULATION DUE TO STEADY FLUX OF MUTATIONS

1969 • 833 citations

Mathematical Population Genetics.

1980 • 756 citations

Population genetics of polymorphism and divergence.

1992 • 637 citations

MUTATION RATE AND DOMINANCE OF GENES AFFECTING VIABILITY IN DROSOPHILA MELANOGASTER

1972 • 494 citations

On the Theory of Partially Inbreeding Finite Populations. I. Partial Selfing

1987 • 343 citations

The effect of strongly selected substitutions on neutral polymorphism: Analytical results based on diffusion theory

1992 • 342 citations

African and North American populations of Drosophila melanogaster are very different at the DNA level

1993 • 322 citations

Inferring the evolutionary histories of the Adh and Adh-dup loci in Drosophila melanogaster from patterns of polymorphism and divergence.

1991 • 295 citations

Male-driven Molecular Evolution: A Model and Nucleotide Sequence Analysis

1987 • 293 citations

Effects of linkage on rates of molecular evolution.

1988 • 286 citations

Evolutionary Rates in Partially Self-Fertilizing Species

1992 • 267 citations

Reduced natural selection associated with low recombination in Drosophila melanogaster.

1993 • 263 citations

Lack of polymorphism on the Drosophila fourth chromosome resulting from selection.

1991 • 257 citations

Analysis of a genetic hitchhiking model, and its application to DNA polymorphism data from Drosophila melanogaster.

1993 • 212 citations

THE EFFECT OF A SELECTED LOCUS ON LINKED NEUTRAL LOCI

1977 • 208 citations

Theoretical foundation of population genetics at the molecular level

1971 • 198 citations

Mutational pressure as the main cause of molecular evolution and polymorphism

1974 • 171 citations

Theoretical Aspects of Population Genetics.

1972 • 150 citations

How much do we know about spontaneous human mutation rates?

1993 • 148 citations

The genomic mutation rate for fitness in Drosophila

1992 • 133 citations

Non-neutral Evolution: Theories and Molecular Data

1995 • 124 citations

Evolution at the Molecular Level

1992 • 113 citations

EXCESS POLYMORPHISM AT THE Adh LOCUS IN DROSOPHILA MELANOGASTER

1986 • 90 citations

Evident diversity of codon usage patterns of human genes with respect to chromosome banding patterns and chromosome numbers; relation between nucleotide sequence data and cytogenetic data

1991 • 86 citations

The effect of selected linked locus on heterozygosity of neutral alleles (the hitch-hiking effect)

1975 • 86 citations

Reduced levels of DNA polymorphism and fixed between-population differences in the centromeric region of Drosophila ananassae.

1992 • 70 citations

Genetic Recombination: Patterns in the genome

1994 • 36 citations

More mutations in males?

1993 • 13 citations

The genomics generation

1993 • 7 citations