Frequency of blood CX₃CR1‐positive natural killer cells correlates with disease activity in multiple sclerosis patients

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A new class of membrane-bound chemokine with a CX3C motif

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Fractalkine and CX3CR1 Mediate a Novel Mechanism of Leukocyte Capture, Firm Adhesion, and Activation under Physiologic Flow

1998 • 679 citations

Regulation of Experimental Autoimmune Encephalomyelitis by Natural Killer (NK) Cells

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Dual Functions of Fractalkine/CX3C Ligand 1 in Trafficking of Perforin+/Granzyme B+ Cytotoxic Effector Lymphocytes That Are Defined by CX3CR1 Expression

2002 • 320 citations

Fractalkine (CX3CL1) as an amplification circuit of polarized Th1 responses

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Calcein-Acetyoxymethyl Cytotoxicity Assay: Standardization of a Method Allowing Additional Analyses on Recovered Effector Cells and Supernatants

2001 • 296 citations

Molecular Uncoupling of Fractalkine-mediated Cell Adhesion and Signal Transduction

1999 • 242 citations

Expression of fractalkine (CX3CL1) and its receptor, CX3CR1, during acute and chronic inflammation in the rodent CNS

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Gene expression profile in multiple sclerosis patients and healthy controls: identifying pathways relevant to disease

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Cutting Edge: Molecular Portrait of Human Autoimmune Disease

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Complex immunomodulatory effects of interferon‐β in multiple sclerosis include the upregulation of T helper 1‐associated marker genes

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A high-density probe array sample preparation method using 10- to 100-fold fewer cells

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Blood transcriptional signatures of multiple sclerosis: Unique gene expression of disease activity

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Migration of CX3CR1‐positive T cells producing type 1 cytokines and cytotoxic molecules into the synovium of patients with rheumatoid arthritis

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Key issues in the diagnosis and treatment of multiple sclerosis

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The regulatory role of natural killer cells in multiple sclerosis

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Natural killer type 2 bias in remission of multiple sclerosis

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The Role of NK Cells in Autoimmune Disease

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The immunoregulatory effects of NK cells: the role of TGF-β and implications for autoimmunity

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A role for natural killer cells in the immunopathogenesis of multiple sclerosis

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CSF and serum levels of soluble fractalkine (CX3CL1) in inflammatory diseases of the nervous system

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CX₃CL1 and CX₃CR1 Expression in Human Brain Tissue: Noninflammatory Control versus Multiple Sclerosis

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Clinical relapses of multiple sclerosis are associated with ‘novel’ valleys in natural killer cell functional activity

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Expression of fractalkine and its receptor, CX3CR1, in atopic dermatitis: Possible contribution to skin inflammation

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Endogenous and interferon-augmented natural killer cell activity of human peripheral blood mononuclear cells in vitro. Studies of patients with multiple sclerosis, systemic lupus erythematosus or rheumatoid arthritis.

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Membrane‐bound form of fractalkine induces IFN‐γ production by NK cells

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Natural killer cell number and activity in multiple sclerosis

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Natural killer cell activity in multiple sclerosis patients treated with recombinant interferon-α2

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