Antibodies against lysosomal membranes reveal a 100,000-mol-wt protein that cross-reacts with purified H+,K+ ATPase from gastric mucosa.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

“Western Blotting”: Electrophoretic transfer of proteins from sodium dodecyl sulfate-polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A

1981 • 8,657 citations

Phase separation of integral membrane proteins in Triton X-114 solution.

1981 • 3,366 citations

Fluorescence probe measurement of the intralysosomal pH in living cells and the perturbation of pH by various agents.

1978 • 2,146 citations

A TECHNIQUE FOR ULTRACRYOTOMY OF CELL SUSPENSIONS AND TISSUES

1973 • 1,057 citations

Mechanisms for the incorporation of proteins in membranes and organelles.

1982 • 875 citations

Intracellular site of asialoglycoprotein receptor-ligand uncoupling: Double-label immunoelectron microscopy during receptor-mediated endocytosis

1983 • 816 citations

Affinity purification of antibodies from diazotized paper blots of heterogeneous protein samples.

1981 • 815 citations

Recycling receptors: The round-trip itinerary of migrant membrane proteins

1983 • 780 citations

Rapid acidification of endocytic vesicles containing α2-macroglobulin

1982 • 672 citations

A modified method for the isolation of the plasma membrane from rat liver

1970 • 574 citations

Sizing of protein A-colloidal gold probes for immunoelectron microscopy.

1981 • 573 citations

Weak bases and ionophores rapidly and reversibly raise the pH of endocytic vesicles in cultured mouse fibroblasts.

1982 • 569 citations

The galactose-specific recognition system of mammalian liver: The route of ligand internalization in rat hepatocytes

1980 • 484 citations

The Golgi Apparatus: Two Organelles in Tandem

1981 • 438 citations

Reconstitution of a Calcium Pump Using Defined Membrane Components

1974 • 420 citations

Antibodies to the Golgi complex and the rough endoplasmic reticulum.

1982 • 418 citations

Penetration of semliki forest virus from acidic prelysosomal vacuoles

1983 • 411 citations

The receptosome: An intermediate organelle of receptor-mediated endocytosis in cultured fibroblasts

1980 • 398 citations

Identification and characterization of a proton pump on lysosomes by fluorescein-isothiocyanate-dextran fluorescence.

1982 • 379 citations

The Phosphomannosyl Recognition System for Intracellular and Intercellular Transport of Lysosomal Enzymes

1982 • 379 citations

Acidification of macrophage and fibroblast endocytic vesicles in vitro.

1983 • 331 citations

Golgi membranes contain an electrogenic H+ pump in parallel to a chloride conductance.

1983 • 310 citations

The mannose-6-phosphate receptor for lysosomal enzymes is concentrated in cis Golgi cisternae

1984 • 291 citations

Clathrin-coated vesicles contain an ATP-dependent proton pump.

1983 • 284 citations

SEGREGATION AND PACKAGING OF GRANULE ENZYMES IN EOSINOPHILIC LEUKOCYTES

1970 • 268 citations

ATP-dependent acidification of intact and disrupted lysosomes. Evidence for an ATP-driven proton pump.

1981 • 255 citations

Biosynthesis of lysosomal hydrolases: their synthesis in bound polysomes and the role of co- and post-translational processing in determining their subcellular distribution

1982 • 246 citations

Evidence for the sorting of endocytic vesicle contents during the receptor-mediated transport of IgG across the newborn rat intestine.

1981 • 244 citations

Phosphomannosyl-enzyme receptors in rat liver. Subcellular distribution and role in intracellular transport of lysosomal enzymes.

1980 • 231 citations

Acidification of endocytic vesicles by an ATP-dependent proton pump.

1983 • 217 citations

[37] Immunoelectron microscopy using thin, frozen sections: Application to studies of the intracellular transport of Semliki Forest virus spike glycoproteins

1983 • 212 citations

Passage of viral membrane proteins through the Golgi complex

1981 • 205 citations

Viral membrane proteins acquire galactose in trans Golgi cisternae during intracellular transport

1982 • 201 citations

The role of intermediate vesicles in the adsorptive endocytosis and transport of ligand to lysosomes by human fibroblasts.

1983 • 196 citations

Biosynthesis of a lysosomal enzyme. Partial structure of two transient and functionally distinct NH2-terminal sequences in cathepsin D.

1981 • 188 citations

Biosynthesis and turnover of the mannose 6-phosphate receptor in cultured Chinese hamster ovary cells.

1983 • 169 citations

Intracellular distributions of mechanochemical proteins in cultured fibroblasts

1977 • 162 citations

Characterization of an integral membrane glycoprotein associated with the microfilaments of pig intestinal microvilli.

1983 • 136 citations

The outer membrane of yeast mitochondria: isolation of outside-out sealed vesicles

1983 • 133 citations

Multiple pathways of exocytosis, endocytosis, and membrane recycling: validation of a Golgi route.

1983 • 126 citations

On the preparation and some properties of closed membrane vesicles from hog duodenal and jejunal brush border

1973 • 126 citations

Polymerization and Immobilization of Proteins Using Ethylchloroformate and Glutaraldehyde

1976 • 123 citations

Heterogeneity of lysosomes originating from rat liver parenchymal cells. Metabolic relationship of subpopulations separated by density-gradient centrifugation

1978 • 116 citations

Synthesis of phosphorylated recognition marker in lysosomal enzymes is located in the cis part of Golgi apparatus.

1982 • 106 citations

A NEW METHOD FOR THE PREPARATION OF RAT LIVER LYSOSOMES

1970 • 103 citations

Acridine Orange as a Fluorescent Probe for Lysosomal Proton Pump1

1982 • 99 citations

[48] Fluorescent localization of contractile proteins in tissue culture cells

1982 • 96 citations

Entry of macro molecular tracers into cells fixed with low concentrations of aldehydes

1978 • 90 citations

Human lysosomes can be purified from diploid skin fibroblasts by free-flow electrophoresis.

1980 • 84 citations

Molecular weight and stoichiometry of the sodium- and potassium-activated adenosine triphosphatase subunits.

1981 • 81 citations

Electron‐microscopic cytochemical studies on the secretory process in rat prolactin cells in primary culture

1980 • 75 citations

ATP-dependent acidification of membrane vesicles isolated from purified rat liver lysosomes. Acidification activity requires phosphate.

1983 • 69 citations

Subfractionation of rat liver Golgi apparatus: separation of enzyme activities involved in the biosynthesis of the phosphomannosyl recognition marker in lysosomal enzymes.

1983 • 60 citations

MECHANISTIC ASPECTS OF GASTRIC (H⁺+ K⁺)‐ATPase*

1982 • 60 citations

[33] Use of immunocytochemical techniques in studying the biogenesis of cell surfaces in polarized epithelia

1983 • 59 citations

pH changes in pinosomes and phagosomes in the ameba, Chaos carolinensis.

1982 • 53 citations

Optimal techniques for the immunocytochemical demonstration of?-thromboglobulin, platelet factor 4, and fibrinogen in the alpha granules of unstimulated platelets

1984 • 51 citations

Properties of N-acetyl-beta-D-hexosaminidase from isolated normal and I-cell lysosomes.

1981 • 49 citations

Purification and characterization of human lysosomes from EB-virus transformed lymphoblasts

1981 • 42 citations

The acidification of rat liver lysosomes in vitro: A role for the membranous ATPase as a proton pump

1979 • 37 citations

Studies on (K+ + H+)-ATPase. V. Chemical composition and molecular weight of the catalytic subunit

1982 • 34 citations

The cellular processing of lysosomal enzymes and related proteins

2005 • 31 citations

Is there a plasma membrane-located anion-sensitive ATPase? III. Identity of the erythrocyte enzyme with (Ca2+ + Mg2+)-ATPase

1978 • 19 citations

Lysosome proton pump identified

1982 • 15 citations