Biosynthesis of a lysosomal enzyme. Partial structure of two transient and functionally distinct NH2-terminal sequences in cathepsin D.

Intracellular Aspects of the Process of Protein Synthesis

1975 • 3,560 citations

Transfer of proteins across membranes. I. Presence of proteolytically processed and unprocessed nascent immunoglobulin light chains on membrane-bound ribosomes of murine myeloma.

1975 • 3,026 citations

Intracellular protein topogenesis

1980 • 1,378 citations

Proteinases in mammalian cells and tissues

1978 • 981 citations

Biosynthesis of lysosomal enzymes in fibroblasts. Synthesis as precursors of higher molecular weight.

1980 • 809 citations

GOLGI APPARATUS, GERL, AND LYSOSOMES OF NEURONS IN RAT DORSAL ROOT GANGLIA, STUDIED BY THICK SECTION AND THIN SECTION CYTOCHEMISTRY

1971 • 583 citations

Phosphohexosyl components of a lysosomal enzyme are recognized by pinocytosis receptors on human fibroblasts.

1977 • 580 citations

Purification of a membrane-associated protein complex required for protein translocation across the endoplasmic reticulum.

1980 • 502 citations

Mechanism of action of tunicamycin on the UDP-GlcNAc:dolichyl-phosphate GlcNAc-1-phosphate transferase

1979 • 411 citations

A recognition marker required for uptake of a lysosomal enzyme by cultured fibroblasts

1974 • 281 citations

Suppression of glycoprotein formation of Semliki Forest, influenza, and avian sarcoma virus by tunicamycin

1976 • 254 citations

Early events in the biosynthesis of the lysosomal enzyme cathepsin D.

1979 • 233 citations

Biosynthetic intermediates of beta-glucuronidase contain high mannose oligosaccharides with blocked phosphate residues.

1980 • 225 citations

On the Structure of Bovine Pancreatic Ribonuclease B

1964 • 196 citations

Cell-free synthesis of fish preproinsulin, and processing by heterologous mammalian microsomal membranes.

1977 • 182 citations

Identification of a rat liver alpha-N-acetylglucosaminyl phosphodiesterase capable of removing “blocking” alpha-N-acetylglucosamine residues from phosphorylated high mannose oligosaccharides of lysosomal enzymes.

1980 • 174 citations

Biosynthesis of the Vacuolar Yeast Glycoprotein Carboxypeptidase Y

1978 • 164 citations

Regulation of the production of secretory proteins: Intracellular degradation of newly synthesized “defective” collagen

1980 • 164 citations

[63] endo-β-N-Acetylglucosaminidase from Streptomyces plicatus

1978 • 149 citations

Phosphorylated oligosaccharides in lysosomal enzymes: identification of alpha-N-acetylglucosamine(1)phospho(6)mannose diester groups.

1980 • 131 citations

Cathepsin D isozymes from porcine spleens. Large scale purification and polypeptide chain arrangements.

1979 • 127 citations

A role for oligosaccharides in glycoprotein biosynthesis

1980 • 117 citations

Biosynthesis of two lysosomal enzymes in macrophages. Evidence for a precursor of beta-galactosidase.

1979 • 101 citations

Maturation of alpha-L-iduronidase in cultured human fibroblasts.

1981 • 97 citations

The Amino-terminal Sequence of Porcine Pepsinogen

1968 • 90 citations

Biosynthesis of lysosomal enzymes

1980 • 87 citations

N-Terminal Amino Acid Sequences of Pepsinogens from Dogfish and Seal and of Bovine Pepsinogen B.

1976 • 28 citations