Megalin-dependent cubilin-mediated endocytosis is a major pathway for the apical uptake of transferrin in polarized epithelia

Cloning and characterization of a mammalian proton-coupled metal-ion transporter

1997 • 3,130 citations

Identification of the haemoglobin scavenger receptor

2001 • 1,610 citations

A Novel Mammalian Iron-regulated Protein Involved in Intracellular Iron Metabolism

2000 • 1,259 citations

Microcytic anaemia mice have a mutation in Nramp2, a candidate iron transporter gene

1997 • 1,178 citations

pH and the recycling of transferrin during receptor-mediated endocytosis.

1983 • 1,165 citations

An Endocytic Pathway Essential for Renal Uptake and Activation of the Steroid 25-(OH) Vitamin D3

1999 • 989 citations

Molecular Cloning of Transferrin Receptor 2

1999 • 638 citations

Complete cloning and sequencing of rat gp330/"megalin," a distinctive member of the low density lipoprotein receptor gene family.

1994 • 550 citations

HFE gene knockout produces mouse model of hereditary hemochromatosis

1998 • 535 citations

Defective forebrain development in mice lacking gp330/megalin.

1996 • 485 citations

A high yield preparation for rat kidney brush border membranes Different behaviour of lysosomal markers

1981 • 444 citations

Cubilin is an albumin binding protein important for renal tubular albumin reabsorption

2000 • 312 citations

Transferrin receptor 2: Continued expression in mouse liver in the face of iron overload and in hereditary hemochromatosis

2000 • 276 citations

The intrinsic factor–vitamin B12 receptor, cubilin, is a high-affinity apolipoprotein A-I receptor facilitating endocytosis of high-density lipoprotein

1999 • 268 citations

Cellular iron metabolism

1999 • 263 citations

The Intrinsic Factor-Vitamin B12 Receptor and Target of Teratogenic Antibodies Is a Megalin-binding Peripheral Membrane Protein with Homology to Developmental Proteins

1998 • 254 citations

Glomerular protein sieving and implications for renal failure in Fanconi syndrome

2001 • 235 citations

Managed care for viruses

1997 • 203 citations

Molecular mechanisms of iron uptake in eukaryotes

1996 • 184 citations

Iron homeostasis: new tales from the crypt

2000 • 181 citations

M<scp>EGALIN</scp>- <scp>AND</scp> C<scp>UBILIN</scp>-M<scp>EDIATED</scp> E<scp>NDOCYTOSIS OF</scp> P<scp>ROTEIN</scp>-B<scp>OUND</scp> V<scp>ITAMINS</scp>, L<scp>IPIDS</scp>, <scp>AND</scp> H<scp>ORMONES IN</scp> P<scp>OLARIZED</scp> E<scp>PITHELIA</scp>

2001 • 176 citations

The Human Intrinsic Factor-Vitamin B12 Receptor,Cubilin: Molecular Characterization and Chromosomal Mapping of the Gene to 10p Within the Autosomal Recessive Megaloblastic Anemia (MGA1) Region

1998 • 161 citations

Cubilin, the endocytic receptor for intrinsic factor-vitamin B ₁₂ complex, mediates high-density lipoprotein holoparticle endocytosis

1999 • 154 citations

Segmental distribution of the endocytosis receptor gp330 in renal proximal tubules.

1995 • 149 citations

Defective Recovery and Severe Renal Damage After Acute Hemolysis in Hemopexin-Deficient Mice

1999 • 143 citations

Characterization of a 280-kD protein restricted to the coated pits of the renal brush border and the epithelial cells of the yolk sac. Teratogenic effect of the specific monoclonal antibodies.

1988 • 137 citations

Structural Requirements for Basolateral Sorting of the Human Transferrin Receptor in the Biosynthetic and Endocytic Pathways of Madin-Darby Canine Kidney Cells

1997 • 129 citations

Transport of molecules across renal glomerular capillaries

1976 • 124 citations

Expression of transferrin receptor on murine hematopoietic progenitors

1984 • 112 citations

Defective brush-border expression of intrinsic factor-cobalamin receptor in canine inherited intestinal cobalamin malabsorption

1991 • 106 citations

Nephron endowment in glial cell line-derived neurotrophic factor (GDNF) heterozygous mice

2001 • 92 citations

Transferrin receptor distribution and regulation in the rat small intestine

1990 • 79 citations

A Two-receptor Pathway for Catabolism of Clara Cell Secretory Protein in the Kidney

2001 • 68 citations

Characterization of receptors for α2-macroglobulin-trypsin complex in rat hepatocytes

1986 • 53 citations

Coexpression in humans by kidney and fetal envelopes of a 280 kDa-coated pit-restricted protein. Similarity with the murine target of teratogenic antibodies.

1992 • 39 citations

Iron uptake in relation to transferrin degradation in brain and other tissues of rats

1992 • 30 citations

Cell cycle‐related proteins: a flow cytofluorometric study in human tumors

1988 • 28 citations

Internalization and recycling of glycoprotein 280 in BN/MSV yolk sac epithelial cells: a model system of relevance to receptor-mediated endocytosis in the renal proximal tubule.

1997 • 25 citations

The control of transferrin receptor synthesis in mitogen-stimulated human lymphocytes

1984 • 24 citations

Dietary protein alters tubular iron accumulation after partial nephrectomy

1994 • 23 citations

Uptake and processing of 59Fe-labelled and 125I-labelled rat transferrin by early organogenesis rat conceptuses in vitro

1997 • 14 citations

Iron homeostasis: new tales from the crypt

2000 • 9 citations

Inhibition of endosome fusion in primary hepatocytes prevents asialoglycoprotein degradation but not uptake of transferrin iron demonstrating that intracellular iron release occurs from early endosomes

2000 • 6 citations