Comparison of the mutagenic and clastogenic activity of amsacrine and other DNA-intercalating drugs in cultured V79 Chinese hamster cells.

Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals.

1975 • 3,362 citations

In situ detection of mycoplasma contamination in cell cultures by fluorescent Hoechst 33258 stain

1977 • 1,743 citations

The production of micronuclei from chromosome aberrations in irradiated cultures of human lymphocytes

1976 • 816 citations

Protein-associated deoxyribonucleic acid strand breaks in L1210 cells treated with the deoxyribonucleic acid intercalating agents 4'-(9-acridinylamino)methanesulfon-m-anisidide and adriamycin

1981 • 382 citations

GENETICS OF SOMATIC MAMMALIAN CELLS

1956 • 378 citations

Mutagenesis by chemical agents in V79 Chinese hamster cells: A review and analysis of the literature

1981 • 297 citations

A comparison of diameters of micronuclei induced by clastogens and by spindle poisons

1980 • 262 citations

Genetics of somatic mammalian cells. IX. Quantitation of mutagenesis by physical and chemical agents

1969 • 245 citations

Chapter 7: Isolation of Mutants of Cultured Mammalian Cells

1973 • 232 citations

The carcinogenicity of anticancer drugs: A hazard in man

1976 • 189 citations

X-ray-induced Chromosome Damage in Live Mammalian Cells, and Improved Measurements of Its Effects on Their Colony-forming Ability

1982 • 135 citations

Do radiation-induced thioguanine-resistant mutants of cultured mammalian cells arise by HGPRT gene mutation or X-chromosome rearrangement?

1978 • 126 citations

Mutagenic responses of thirteen anticancer drugs on mutation induction at multiple genetic loci and on sister chromatid exchanges in Chinese hamster ovary cells.

1983 • 117 citations

DNA-binding characteristics of acridinylmethanesulphonanilide drugs: Comparison with antitumour properties

1976 • 114 citations

Interaction of the antitumor drug 4'-(9-acridinylamino)methanesulfon-m-anisidide and related acridines with nucleic acids.

1981 • 98 citations

Mutagenesis in S49 mouse lymphoma cells: induction of resistance to ouabain, 6-thioguanine, and dibutyryl cyclic AMP.

1977 • 90 citations

The induction of thioguanine-resistant mutants of Chinese hamster cells by γ-rays

1977 • 88 citations

Relative mutagenicity of antineoplastic drugs and other alkylating agents in V79 chinese hamster cells, independence of cytotoxic and mutagenic responses

1980 • 80 citations

Drug-induced cancer

1981 • 75 citations

Potential antitumor agents. 35. Quantitative relationships between antitumor (L1210) potency and DNA binding for 4'-(9-acridinylamino)methanesulfon-m-anisidide (m-AMSA) analogs

1981 • 69 citations

REQUIREMENT FOR CELL DISPERSION PRIOR TO SELECTION OF INDUCED AZAGUANINE-RESISTANT COLONIES OF CHINESE HAMSTER CELLS

1975 • 68 citations

Mutation to ouabain-resistance in Chinese hamster cells: Induction by ethyl methanesulphonate and lack of induction by ionising radiation

1978 • 62 citations

Mutagenic responses of five independent geentic loci in CHO cells to a variety of mutagens

1982 • 60 citations

Cell-Cycle-Specific Chromosome Damage Following Treatment of Cultured Chinese Hamster Cells With 4′-[(9-Acridinyl-amino] methanesulphon-m-anisidide-HCl2

1978 • 56 citations

Different incidence of breast carcinomas or fibroadenomas in daunomycin or adriamycin treated rats

1971 • 51 citations

Ouabain‐resistant human lymphoblastoid lines altered in the (Na⁺ + K⁺)‐dependent ATPase membrane transport system

1976 • 46 citations

Current status of amsacrine (AMSA) combination chemotherapy programs in acute leukemia.

1983 • 38 citations

Platinum-induced mutations to 8-azaguanine resistance in Chinese hamster ovary cells

1979 • 36 citations

Human pharmacokinetics of a new acridine derivative, 4'-(9-acridinylamino)methanesulfon-m-anisidide (NSC 249992).

1983 • 32 citations

Comparative genotoxicity of adriamycin and menogarol, two anthracycline antitumor agents.

1983 • 32 citations

Comparative studies of mutagenic, DNA binding and antileukaemic properties of 9-anilinoacridine derivatives and related compounds

1983 • 27 citations

The effect of variable serum factors and clonal morphology on the ability to detect hypoxanthine guanine phosphoribosyl transferase (HPRT) deficient variants in cultured Chinese hamster cells

1975 • 23 citations

Multinucleate Cells and Micronucleus Formation in Cultured Human Cells Exposed to 12 MeV Protons and γ-rays

1980 • 21 citations

Quantitative forward-mutation specificity of mono-functional alkylating agents, ICR-191, and aflatoxin B1 in mouse lymphoma cells

1982 • 13 citations

Phase II. Trial of 4'-(9-acridinylamino)methanesulfon-m-anisidide (AMSA) in the treatment of advanced non-Hodgkin's lymphoma.

1980 • 12 citations

9-Aminoacridine - a frameshift mutagen for Salmonella typhimurium TA 1537 inactive at the hgprt locus in human lymphoblasts

1977 • 10 citations

Relative sensitivity of V79 and V79/79 cells to spontaneous and induced mutation to 6-thioguanine and ouabain resistance

1982 • 7 citations