Quantitative forward-mutation specificity of mono-functional alkylating agents, ICR-191, and aflatoxin B1 in mouse lymphoma cells

Carcinogens are Mutagens: A Simple Test System Combining Liver Homogenates for Activation and Bacteria for Detection

1973 • 2,275 citations

An Improved Bacterial Test System for the Detection and Classification of Mutagens and Carcinogens

1973 • 1,519 citations

Detection of carcinogens as mutagens: bacterial tester strains with R factor plasmids.

1975 • 1,030 citations

The Biochemistry of Mutagenesis

1976 • 421 citations

Ouabain-resistant mutants of mouse and hamster cells in culture

1974 • 393 citations

An improved bacterial test system for the detection and classification of mutagens and carcinogens

1973 • 295 citations

Characterization of a new photoaffinity derivative of ouabain: labeling of the large polypeptide and of a proteolipid component of the (sodium-potassium ion)-dependent ATPase

1978 • 282 citations

A quantitative assay of mutation induction at the hypoxanthine-guanine phosphoribosyl transferase locus in Chinese hamster ovary cells (CHO/HGPRT system): Development and definition of the system

1977 • 267 citations

Mutations causing charge alterations in regulatory subunits of the cAMP-dependent protein kinase of cultured S49 lymphoma cells

1977 • 222 citations

Induction of Cytolysis of Cultured Lymphoma Cells by Adenosine 3′:5′-Cyclic Monophosphate and the Isolation of Resistant Variants

1973 • 176 citations

Linear dose —response relationships after prolonged expression times in V-79 Chinese hamster cells

1976 • 172 citations

Cyclic AMP-Dependent Protein Kinase: Pivotal Role in Regulation of Enzyme Induction and Growth

1975 • 164 citations

A comparison of the 8-azaguanine and ouabain-resistance systems for the selection of induced mutant Chinese hamster cells

1975 • 157 citations

A quantitative assay of mutation induction at the hypoxanthine-guanine phosphoribosyl transferase locus in Chinese hamster ovary cells (CHO/HGPRT system): Utilization with a variety of mutagenic agents

1977 • 151 citations

Liver homogenate-mediated mutagenesis in Chinese hamster V79 cells by polycyclic aromatic hydrocarbons and aflatoxins

1977 • 150 citations

FRAMESHIFT MUTATIONS

1974 • 135 citations

Somatic genetic analysis of cyclic AMP action: Selection of unresponsive mutants

1975 • 132 citations

Relative sensitivities of forward and reverse mutation assays in Salmonella typhimurium.

1978 • 129 citations

A mutational assay system for L5178Y mouse lymphoma cells, using hypoxanthine-guanine-phosphoribosyl-transferase (HGPRT) -deficiency as marker. The occurrence of a long expression time for mutations induced by X-rays and EMS

1975 • 114 citations

Kinase-negative mutants of S49 mouse lymphoma cells carry a trans-dominant mutation affecting expression of cAMP-dependent protein kinase

1978 • 99 citations

Somatic genetic analysis of cyclic AMP action: Characterization of unresponsive mutants

1975 • 96 citations

Phenotype expression time of mutagen-induced 6-thioguanine resistance in Chinese hamster ovary cells (CHO/HGPRT system)

1979 • 92 citations

Cell specificity in metabolic activation of aflatoxin B1 and benzo(a)pyrene to mutagens for mammalian cells

1978 • 87 citations

Somatic cell genetic evidence for X-chromosome linkage of three enzymes in the mouse

1976 • 86 citations

Genetic markers for quantitative mutagenesis studies in Chinese hamster ovary cells Characteristics of some recently developed selective systems

1980 • 78 citations

Ethyl methanesulphonate mutagenesis with L5178Y mouse lymphoma cells: A comparison of ouabain, thioguanine and excess thymidine resistance

1976 • 75 citations

Mutation to ouabain-resistance in Chinese hamster cells: Induction by ethyl methanesulphonate and lack of induction by ionising radiation

1978 • 62 citations

INDUCTION OF THIOGUANINE- AND OUABAIN-RESISTANT MUTANTS AND SINGLE-STRAND BREAKS IN THE DNA OF CHINESE HAMSTER OVARY CELLS BY 3H-THYMIDINE

1977 • 60 citations

The relation between induced mutation frequency and cell survival — A theoretical approach and an examination of experimental data for eukaryotes

1977 • 59 citations

Efficient detection of soft agar grown colonies using a tetrazolium salt

1975 • 56 citations

Mutagenicity and cytotoxicity of nineteen heterocyclic mustards (ICR compounds) in cultured mammalian cells.

1979 • 31 citations

Design and analysis of experiments on mutagenicity

1978 • 22 citations

Intragenic mutational spectra and hot spots

1976 • 14 citations