Essential Role of CD8+CD122+ Regulatory T Cells in the Recovery from Experimental Autoimmune Encephalomyelitis

Regulatory T Cells

2000 • 1,827 citations

Cutting Edge: CD4+CD25+ Regulatory T Cells Suppress Antigen-Specific Autoreactive Immune Responses and Central Nervous System Inflammation During Active Experimental Autoimmune Encephalomyelitis

2002 • 779 citations

A Pathogenic Role for Myelin-Specific Cd8+ T Cells in a Model for Multiple Sclerosis

2001 • 650 citations

Active induction of experimental allergic encephalomyelitis

2006 • 527 citations

Myelin Antigen-Specific CD8+ T Cells Are Encephalitogenic and Produce Severe Disease in C57BL/6 Mice

2001 • 437 citations

Immunological Aspects of Experimental Allergic Encephalomyelitis and Multiple Sclerosis

1995 • 381 citations

Less Mortality but More Relapses in Experimental Allergic Encephalomyelitis in CD8 ^-/- Mice

1992 • 359 citations

IL-10 is involved in the suppression of experimental autoimmune encephalomyelitis by CD25+CD4+ regulatory T cells

2004 • 354 citations

Role of CD8 ⁺ T Cells in Murine Experimental Allergic Encephalomyelitis

1992 • 351 citations

Cutting Edge: Anti-CD25 Monoclonal Antibody Injection Results in the Functional Inactivation, Not Depletion, of CD4+CD25+ T Regulatory Cells

2006 • 333 citations

Essential Roles of CD8+CD122+ Regulatory T Cells in the Maintenance of T Cell Homeostasis

2004 • 305 citations

Cutting Edge: CD8+CD122+ Regulatory T Cells Produce IL-10 to Suppress IFN-γ Production and Proliferation of CD8+ T Cells

2005 • 268 citations

Myelin oligodendrocyte glycoprotein: a novel candidate autoantigen in multiple sclerosis

1997 • 267 citations

Autoreactive CD8+ T cells in multiple sclerosis: a new target for therapy?

2005 • 249 citations

Myelin proteolipid protein-specific CD4⁺CD25⁺regulatory cells mediate genetic resistance to experimental autoimmune encephalomyelitis

2004 • 186 citations

Specificity, magnitude, and kinetics of MOG‐specific CD8⁺ T cell responses during experimental autoimmune encephalomyelitis

2004 • 137 citations

Glatiramer Acetate: Mechanisms of Action in Multiple Sclerosis

2007 • 136 citations

Regulation of experimental autoimmune encephalomyelitis by CD4+, CD25+ and CD8+ T cells: analysis using depleting antibodies

2004 • 115 citations

Cutting Edge: CD4+CD25+ Regulatory T Cells Contribute to Gender Differences in Susceptibility to Experimental Autoimmune Encephalomyelitis

2005 • 111 citations

CD8+CD28− Regulatory T Lymphocytes Prevent Experimental Inflammatory Bowel Disease in Mice

2006 • 109 citations

Experimental models of multiple sclerosis

2007 • 102 citations

MP4- and MOG:35–55-induced EAE in C57BL/6 mice differentially targets brain, spinal cord and cerebellum☆

2007 • 102 citations

Multi-peptide coupled-cell tolerance ameliorates ongoing relapsing EAE associated with multiple pathogenic autoreactivities

2006 • 87 citations

Temporal expression and cellular origin of CC chemokine receptors CCR1, CCR2 and CCR5 in the central nervous system: insight into mechanisms of MOG-induced EAE

2007 • 81 citations

The immunoregulatory effects of Qa‐1

2006 • 72 citations

CD25 regulatory T cells determine secondary but not primary remission in EAE: Impact on long-term disease progression

2005 • 66 citations

A model of experimental autoimmune encephalomyelitis (EAE) in C57BL/6 mice for the characterisation of intervention therapies

2007 • 60 citations

Functional properties of myelin oligodendrocyte glycoprotein-reactive T cells in multiple sclerosis patients and controls

2003 • 54 citations

Role of MOG-stimulated Th1 type ‘light up’ (GFP+) CD4+T Cells for the Development of Experimental Autoimmune Encephalomyelitis (EAE)

2001 • 53 citations

The Human T Cell Response to Myelin Oligodendrocyte Glycoprotein: A Multiple Sclerosis Family-Based Study

2002 • 47 citations

Antigen-Specific Suppression of Experimental Autoimmune Encephalomyelitis by a Novel Bifunctional Peptide Inhibitor

2007 • 46 citations

The cytokine signature of MOG-specific CD4 cells in the EAE of C57BL/6 mice

2005 • 40 citations

Experimental Autoimmune Demyelination: Chronic Relapsing Models and Their Therapeutic Implications for Multiple Sclerosis^a

1984 • 30 citations

Paralysis of CD4+CD25+ regulatory T cell response in chronic autoimmune encephalomyelitis

2007 • 30 citations

Control of experimental autoimmune encephalomyelitis by CD4+ suppressor T cells: Peripheral versus in situ immunoregulation

2007 • 24 citations

An MHC anchor‐substituted analog of myelin oligodendrocyte glycoprotein 35–55 induces IFN‐γ and autoantibodies in the absence of experimental autoimmune encephalomyelitis and optic neuritis

2004 • 19 citations

Evaluation of a rat model of experimental autoimmune encephalomyelitis with human MBP as antigen.

2004 • 11 citations

Adoptive transfer of myelin basic protein-induced experimental autoimmune encephalomyelitis between SJL and B10.S mice: Correlation of priming milieus with susceptibility and resistance phenotypes

2006 • 6 citations