The cytokine signature of MOG-specific CD4 cells in the EAE of C57BL/6 mice

Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

1999 • 5,659 citations

Differential Expression of Chemokine Receptors and Chemotactic Responsiveness of Type 1 T Helper Cells (Th1s) and Th2s

1998 • 2,048 citations

B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: Application to autoimmune disease therapy

1995 • 1,695 citations

Memory CD8+ T cell differentiation: initial antigen encounter triggers a developmental program in naïve cells

2001 • 1,277 citations

T-cell priming by type-1and type-2 polarized dendritic cells: the concept of a third signal

1999 • 957 citations

Cutting Edge: CD4+CD25+ Regulatory T Cells Suppress Antigen-Specific Autoreactive Immune Responses and Central Nervous System Inflammation During Active Experimental Autoimmune Encephalomyelitis

2002 • 779 citations

Augmentation of demyelination in rat acute allergic encephalomyelitis by circulating mouse monoclonal antibodies directed against a myelin/oligodendrocyte glycoprotein.

1988 • 721 citations

B7-1 and B7-2 do not deliver identical costimulatory signals, since B7-2 but not B7-1 preferentially costimulates the initial production of IL-4

1995 • 577 citations

An Interleukin (IL)-10/IL-12 Immunoregulatory Circuit Controls Susceptibility to Autoimmune Disease

1998 • 479 citations

IL-6-Deficient Mice Are Resistant to Experimental Autoimmune Encephalomyelitis: Roles of IL-6 in the Activation and Differentiation of Autoreactive T Cells

1998 • 448 citations

Biotechnological agents for the immunotherapy of multiple sclerosis. Principles, problems and perspectives

1997 • 365 citations

Th2 Lineage Commitment and Efficient IL-4 Production Involves Extended Demethylation of the IL-4 Gene

2002 • 328 citations

IL-6-deficient mice resist myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis

1998 • 307 citations

A few autoreactive cells in an autoimmune infiltrate control a vast population of nonspecific cells: a tale of smart bombs and the infantry.

1996 • 224 citations

B-cell-deficient mice develop experimental allergic encephalomyelitis with demyelination after myelin oligodendrocyte glycoprotein sensitization.

1998 • 208 citations

Differential Expression of Inflammatory Cytokines Parallels Progression of Central Nervous System Pathology in Two Clinically Distinct Models of Multiple Sclerosis

1998 • 200 citations

Dendritic cell subsets and the regulation of Th1/Th2 responses

2001 • 197 citations

De Novo Central Nervous System Processing of Myelin Antigen Is Required for the Initiation of Experimental Autoimmune Encephalomyelitis

2002 • 191 citations

Cutting Edge: B Cell-Deficient Mice Develop Experimental Allergic Encephalomyelitis with Demyelination After Myelin Oligodendrocyte Glycoprotein Sensitization

1998 • 177 citations

Single-Cytokine-Producing CD4 Memory Cells Predominate in Type 1 and Type 2 Immunity

2000 • 174 citations

IL-18 Directs Autoreactive T Cells and Promotes Autodestruction in the Central Nervous System Via Induction of IFN-γ by NK Cells

2000 • 173 citations

Pertussis Toxin Modulates the Immune Response to Neuroantigens Injected in Incomplete Freund’s Adjuvant: Induction of Th1 Cells and Experimental Autoimmune Encephalomyelitis in the Presence of High Frequencies of Th2 Cells

2002 • 159 citations

Chronic relapsing experimental autoimmune encephalomyelitis with a delayed onset and an atypical clinical course, induced in PL/J mice by myelin oligodendrocyte glycoprotein (MOG)‐derived peptide: Preliminary analysis of MOG T cell epitopes

1995 • 157 citations

T-Cell Apoptosis in Inflammatory Brain Lesions

1998 • 146 citations

Experimental autoimmune encephalomyelitis in IL-4-deficient mice

1997 • 111 citations

Naive T lymphocytes traffic to inflamed central nervous system, but require antigen recognition for activation

2000 • 101 citations

Frequencies of Neuroantigen-Specific T Cells in the Central Nervous System Versus the Immune Periphery During the Course of Experimental Allergic Encephalomyelitis

2001 • 80 citations

Lineage commitment in lymphocytes: controlling the immune response.

2001 • 61 citations

Experimental Autoimmune Encephalomyelitis: CC Chemokine Receptor Expression by Trafficking Cells

2002 • 45 citations

CD43 Modulates Severity and Onset of Experimental Autoimmune Encephalomyelitis

2003 • 39 citations

Indirect IL-4 Pathway in Type 1 Immunity

2002 • 38 citations

Lack of Th2 cytokine increase during spontaneous remission of experimental allergic encephalomyelitis

1998 • 31 citations

Lack of Th2 cytokine increase during spontaneous remission of experimental allergic encephalomyelitis

1998 • 27 citations

Acute and relapsing experimental autoimmune encephalomyelitis in IL-4- and α/β T cell-deficient C57BL/6 mice

1998 • 24 citations

Organ-Specific Cytokine Polarization Induced by Adoptive Transfer of Transgenic T Cells

2002 • 8 citations