Development of Interpretive Breakpoints for Antifungal Susceptibility Testing: Conceptual Framework and Analysis of In Vitro-In Vivo Correlation Data for Fluconazole, Itraconazole, and Candida Infections
Data up to Jan 2025
Total Citations Per Year
Abstract
References (100)
Biostatistical Analysis (2nd ed.).
1986 • 5,963 citations
A Randomized Trial Comparing Fluconazole with Amphotericin B for the Treatment of Candidemia in Patients without Neutropenia
1994 • 1,040 citations
Secular trends in nosocomial primary bloodstream infections in the United States, 1980–1989
1991 • 896 citations
Resistance of Candida species to fluconazole
1995 • 890 citations
Fluconazole
1990 • 658 citations
Antibacterial susceptibility tests : Dilution and disk diffusion methods.
1995 • 553 citations
Multicenter evaluation of four methods of yeast inoculum preparation
1988 • 462 citations
Resistance of Candida albicans biofilms to antifungal agents in vitro
1995 • 404 citations
The Clinical Pharmacokinetics of Itraconazole: An Overview
1989 • 381 citations
Pharmacokinetic evaluation of UK-49,858, a metabolically stable triazole antifungal drug, in animals and humans
1985 • 362 citations
Role of pharmacokinetics in the outcome of infections
1988 • 354 citations
Antifungal susceptibility testing
1993 • 351 citations
Epidemiology of oral candidiasis in HIV-infected patients: Colonization, infection, treatment, and emergence of fluconazole resistance
1994 • 321 citations
Treatment of Refractory Disseminated Nontuberculous Mycobacterial Infection With Interferon Gamma: A Preliminary Report
1994 • 297 citations
Pharmacokinetics of itraconazole following oral administration to normal volunteers
1988 • 285 citations
Resistance of Candida albicans to Fluconazole During Treatment of Oropharyngeal Candidiasis in a Patient with AIDS: Documentation by In Vitro Susceptibility Testing and DNA Subtype Analysis
1994 • 271 citations
Listeria monocytogenes in Nature
1971 • 259 citations
Collaborative comparison of broth macrodilution and microdilution antifungal susceptibility tests
1992 • 250 citations
Fluconazole resistance in Candida glabrata
1993 • 246 citations
Pharmacokinetic profile of orally administered itraconazole in human skin
1988 • 243 citations
Emerging fungal pathogens
1989 • 211 citations
Variations in fluconazole susceptibility and electrophoretic karyotype among oral isolates of Candida albicans from patients with AIDS and oral candidiasis
1994 • 205 citations
Detection of amphotericin B-resistant Candida isolates in a broth-based system
1995 • 202 citations
Comparison of Etest and National Committee for Clinical Laboratory Standards broth macrodilution method for antifungal susceptibility testing: enhanced ability to detect amphotericin B-resistant Candida isolates
1995 • 200 citations
Multicenter evaluation of a broth macrodilution antifungal susceptibility test for yeasts
1993 • 197 citations
Microbiological tests to predict treatment outcome in experimental device-related infections due to Staphylococcus aureus
1994 • 194 citations
Collaborative investigation of variables in susceptibility testing of yeasts
1990 • 193 citations
Activity of fluconazole (UK 49,858) and ketoconazole against Candida albicans in vitro and in vivo
1986 • 185 citations
Interaction of Azoles with Rifampin, Phenytoin, and Carbamazepine: In Vitro and Clinical Observations
1992 • 181 citations
Susceptibility testing of fungi: current status of correlation of in vitro data with clinical outcome
1996 • 168 citations
Evaluation of a novel colorimetric broth microdilution method for antifungal susceptibility testing of yeast isolates
1994 • 161 citations
Opportunistic Candidiasis: An Epidemic of the 1980s
1995 • 160 citations
Comparison of Etest and National Committee for Clinical Laboratory Standards broth macrodilution method for azole antifungal susceptibility testing
1995 • 158 citations
Fluconazole-Resistant Candida albicans
1993 • 154 citations
High-dose itraconazole in the treatment of severe mycoses
1991 • 151 citations
Susceptibility testing of Cryptococcus neoformans: a microdilution technique
1992 • 151 citations
Identification of Patients with Acute AIDS-Associated Cryptococcal Meningitis Who Can Be Effectively Treated with Fluconazole: The Role of Antifungal Susceptibility Testing
1996 • 140 citations
Use of amphotericin B with azole antifungal drugs: what are we doing?
1995 • 139 citations
Effect of protein binding of daptomycin on MIC and antibacterial activity
1991 • 134 citations
Quality control guidelines for National Committee for Clinical Laboratory Standards recommended broth macrodilution testing of amphotericin B, fluconazole, and flucytosine
1995 • 130 citations
In vitro pharmacodynamic effects of concentration, pH, and growth phase on serum bactericidal activities of daptomycin and vancomycin
1992 • 125 citations
Interaction of Ketoconazole with Rifampin and Isoniazid
1984 • 123 citations
Correlation between In Vitro and In Vivo Activity of Antifungal Agents against Candida Species
1994 • 120 citations
Safety and pharmacokinetics of fluconazole in children with neoplastic diseases
1992 • 119 citations
Comparison of relative susceptibilities of Candida species to three antifungal agents as determined by unstandardized methods
1987 • 118 citations
Comparison study of broth macrodilution and microdilution antifungal susceptibility tests
1991 • 115 citations
Comparison of broth macrodilution, broth microdilution, and E test antifungal susceptibility tests for fluconazole
1994 • 112 citations
Azole resistance in Candida albicans.
1986 • 97 citations
Pharmacokinetics of 18F-labeled fluconazole in healthy human subjects by positron emission tomography
1993 • 96 citations
The pharmacokinetics of itraconazole in animals and man: an overview
1987 • 93 citations
Ketoconazole therapy of progressive coccidioidomycosis
1988 • 92 citations
Pharmacokinetics and bactericidal rates of daptomycin and vancomycin in intravenous drug abusers being treated for gram-positive endocarditis and bacteremia
1992 • 92 citations
Use of a colorimetric system for yeast susceptibility testing
1995 • 92 citations
In vitro activity of itraconazole against fluconazole-susceptible and -resistant Candida albicans isolates from oral cavities of patients infected with human immunodeficiency virus
1994 • 90 citations
Results of a survey of antifungal susceptibility tests in the United States and interlaboratory comparison of broth dilution testing of flucytosine and amphotericin B
1986 • 84 citations
Fluconazole resistance in Candida in patients with AIDS—A therapeutic approach
1993 • 82 citations
Correlation of in-vitro susceptibility test results with clinical response: a study of azole therapy in AIDS patients
1995 • 78 citations
Susceptibility testing of fungi: current status of the standardization process
1993 • 74 citations
Variations in DNA subtype, antifungal susceptibility, and slime production among clinical isolates of Candida parapsilosis
1995 • 72 citations
Simple method for detecting fluconazole-resistant yeasts with chromogenic agar
1996 • 71 citations
Correlation of In Vitro Azole Susceptibility with In Vivo Response in a Murine Model of Cryptococcal Meningitis
1993 • 71 citations
Antimycotic efficacy of bifonazole in vitro and in vivo.
1983 • 69 citations
Daptomycin or teicoplanin in combination with gentamicin for treatment of experimental endocarditis due to a highly glycopeptide-resistant isolate of Enterococcus faecium
1992 • 69 citations
Effect of protein binding on serum bactericidal activities of ceftazidime and cefoperazone in healthy volunteers
1988 • 66 citations
Fluconazole-resistant Candida in AIDS patients
1993 • 65 citations
Etest for antifungal susceptibility testing of yeasts
1994 • 60 citations
DNA Subtypes and Fluconazole Susceptibilities of Candida albicans Isolates from the Oral Cavities of Patients with AIDS
1995 • 60 citations
Correlation of various in vitro testing methods with clinical outcomes in patients with Bacteroides fragilis group infections treated with cefoxitin: a retrospective analysis
1992 • 57 citations
Azole resistance in oropharyngeal Candida albicans strains isolated from patients infected with human immunodeficiency virus
1994 • 53 citations
Quality control guidelines for National Committee for Clinical Laboratory Standards--recommended broth macrodilution testing of ketoconazole and itraconazole
1996 • 49 citations
Experience with Itraconazole in Deep Mycoses in Northern Italy. Erfahrungen mit Itraconazol bei tieflokalisierten Mykosen in Norditalien
1987 • 47 citations
Strain variation among and antifungal susceptibilities of isolates of Candida krusei
1996 • 45 citations
Steady State Parenteral Kinetics of Fluconazole in Man
1988 • 42 citations
Collaborative evaluation in seven laboratories of a standardized micromethod for yeast susceptibility testing
1988 • 42 citations
In vitro activity of D0870 compared with those of other azoles against fluconazole-resistant Candida spp
1995 • 41 citations
European standards for antibiotic susceptibility testing: Towards a theoretical consensus
1990 • 39 citations
Ketoconazole and fluconazole drug interactions.
1993 • 39 citations
In vitro susceptibilities of clinical yeast isolates to three antifungal agents determined by the microdilution method
1995 • 36 citations
Sublethal Concentrations of Antibiotics, Effects on Bacteria and the Immune System
1982 • 36 citations
Patterns of in vitro activity of itraconazole and imidazole antifungal agents against Candida albicans with decreased susceptibility to fluconazole from Spain
1995 • 36 citations
Clinical Aspects of Tetanus
1989 • 35 citations
Collaborative investigation of broth microdilution and semisolid agar dilution for in vitro susceptibility testing of Candida albicans
1992 • 34 citations
Activity of fluconazole: postantifungal effect, effects of low concentrations and of pretreatment on the susceptibility of Candida albicans to leucocytes
1994 • 31 citations
Is there a correlation between serum antifungal drug concentration and clinical outcome?
1994 • 30 citations
Variation in fluconazole efficacy for Candida albicans strains sequentially isolated from oral cavities of patients with AIDS in an experimental murine candidiasis model
1996 • 29 citations
pH and other effects on the antifungal activity of cilofungin (LY121019)
1989 • 29 citations
Teicoplanin and daptomycin bactericidal activities in the presence of albumin or serum under controlled conditions of pH and ionized calcium
1993 • 29 citations
Effects of Sub‐Inhibitory Concentrations of Antifungal Agents on Adherence of Candida spp. to Buccal Epithelial Cells in Vitro: Die Wirkung subinhibitorischer Antimyzetika‐Konzentrationen auf die Adharenz von Candida‐Arten an Epithelzellen der Mundschleimhaut
1989 • 28 citations
The relevance of pharmacokinetics to in-vitro models: protein binding--does it matter?
1985 • 25 citations
Antifungal activity of a new triazole, D0870, compared with four other antifungal agents tested against clinical isolates of Candida and Torulopsis glabrata
1994 • 24 citations
Human serum enhances the postantibiotic effect of fluoroquinolones against Staphylococcus aureus
1991 • 23 citations
Molecular karyotyping of multiple yeast species isolated from nine patients with AIDS during prolonged fluconazole therapy
1996 • 21 citations
In vivo interaction of ketoconazole and sucralfate in healthy volunteers
1994 • 21 citations
[Multicenter study of the standardization of sensitivity testing of fungi to 5-fluorocytosine and amphotericin B].
1987 • 18 citations
ARTs versns ASTs: where are we going?
1991 • 17 citations
DNA macrorestriction profiles and antifungal susceptibility of Candida (Torulopsis) glabrata
1996 • 17 citations
Antimicrobial Susceptibility Tests: Testing Methods and Interpretive Problems
1994 • 16 citations
Dirithromycin disc susceptibility tests: interpretative criteria and quality control parameters
1993 • 10 citations
Interpretive criteria and quality control guidelines for lomefloxacin and meropenem in susceptibility tests of Haemophilus influenzae using Haemophilus test medium
1992 • 7 citations
Preliminary interpretive susceptibility testing criteria for FK-037 with 30-microgram disks
1994 • 3 citations