Teicoplanin and daptomycin bactericidal activities in the presence of albumin or serum under controlled conditions of pH and ionized calcium

Daptomycin disrupts membrane potential in growing Staphylococcus aureus

1991 • 211 citations

In vitro and in vivo activity of LY 146032, a new cyclic lipopeptide antibiotic

1986 • 170 citations

Single-dose pharmacokinetics and antibacterial activity of daptomycin, a new lipopeptide antibiotic, in healthy volunteers

1992 • 157 citations

Serum Dilution Test for Bactericidal Activity. II. Standardization and Correlation with Antimicrobial Assays and Susceptibility Tests

1977 • 155 citations

Pharmacodynamics of daptomycin and vancomycin on Enterococcus faecalis and Staphylococcus aureus demonstrated by studies of initial killing and postantibiotic effect and influence of Ca2+ and albumin on these drugs

1991 • 142 citations

Effect of protein binding of daptomycin on MIC and antibacterial activity

1991 • 134 citations

Outer membrane permeation of beta-lactam antibiotics in Escherichia coli, Proteus mirabilis, and Enterobacter cloacae

1982 • 116 citations

Assessment of effects of protein binding on daptomycin and vancomycin killing of Staphylococcus aureus by using an in vitro pharmacodynamic model

1990 • 109 citations

Serum Dilution Test for Bactericidal Activity. I. Selection of a Physiologic Diluent

1977 • 102 citations

Antimicrobial activity and spectrum of LY146032, a lipopeptide antibiotic, including susceptibility testing recommendations

1987 • 101 citations

Effects of dosage, peak and trough concentrations in serum, protein binding, and bactericidal rate on efficacy of teicoplanin in a rabbit model of endocarditis

1990 • 98 citations

Pharmacokinetics and bactericidal rates of daptomycin and vancomycin in intravenous drug abusers being treated for gram-positive endocarditis and bacteremia

1992 • 92 citations

Comparative effect of protein binding on the killing activities of teicoplanin and vancomycin

1991 • 90 citations

Inhibition of membrane potential-dependent amino acid transport by daptomycin

1991 • 90 citations

Daptomycin compared with teicoplanin and vancomycin for therapy of experimental Staphylococcus aureus endocarditis

1990 • 63 citations

In vitro activities of daptomycin and other antimicrobial agents against vancomycin-resistant gram-positive bacteria

1989 • 33 citations

Activities of daptomycin and teicoplanin against Staphylococcus haemolyticus and Staphylococcus epidermidis, including evaluation of susceptibility testing recommendations

1989 • 33 citations

Clinical evaluation of teicoplanin fluorescence polarization immunoassay

1991 • 30 citations

Influence of Subinhibitory Concentrations of Cephalosporins on the Serum Sensitivity of Pseudomonas aeruginosa

1990 • 26 citations

Effect of human serum on the bactericidal activity of daptomycin and vancomycin against staphylococcal and enterococcal isolates as determined by time-kill kinetic studies

1990 • 25 citations

Influence of subinhibitory concentrations of loracarbef (LY 163892) and daptomycin (LY 146032) on bacterial phagocytosis, killing and serum sensitivity

1990 • 16 citations

LY146032: activity and resistance development in vitro

1987 • 15 citations

Synergistic Bactericidal Activity of Rat Serum with Vancomycin against Enterococci

1991 • 15 citations

Therapeutic Update on Glycopeptide and Lipopeptide Antibiotics

1988 • 15 citations

Comparison of in vitro Activity of Daptomycin, Vancomycin and Fluoroquinolones in Broth and Serum against <i>Staphylococcus epidermidis</i>as Determined by Time-Kill Kinetics

1989 • 9 citations

Activity of LY146032 and vancomycin against coagulase-negative staphylococci

1987 • 4 citations