Differential roles for Fos and Jun in DNA-binding: redoxdependent and independent functions

Stimulus-Transcription Coupling in the Nervous System: Involvement of the Inducible Proto-Oncogenes fos and jun

1991 • 2,666 citations

Fos and jun: The AP-1 connection

1988 • 1,597 citations

Redox Regulation of Fos and Jun DNA-Binding Activity in Vitro

1990 • 1,592 citations

Phosphorylation of c-jun mediated by MAP kinases

1991 • 1,495 citations

The c-fos protein interacts with c-JunAP-1 to stimulate transcription of AP-1 responsive genes

1988 • 1,352 citations

Cross-family dimerization of transcription factors Fos/Jun and ATF/CREB alters DNA binding specificity.

1991 • 1,300 citations

Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA-binding activity

1991 • 1,071 citations

Scissors-Grip Model for DNA Recognition by a Family of Leucine Zipper Proteins

1989 • 996 citations

The GCN4 basic region leucine zipper binds DNA as a dimer of uninterrupted α Helices: Crystal structure of the protein-DNA complex

1992 • 964 citations

Redox activation of Fos-Jun DNA binding activity is mediated by a DNA repair enzyme.

1992 • 920 citations

DNA binding activities of three murine Jun proteins: Stimulation by Fos

1988 • 850 citations

The role of the leucine zipper in the fos–jun interaction

1988 • 836 citations

Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73

1991 • 800 citations

Identification and characterization of Ref-1, a nuclear protein that facilitates AP-1 DNA-binding activity.

1992 • 702 citations

Jun-B differs in its biological properties from, and is a negative regulator of, c-Jun

1989 • 698 citations

Leucine Repeats and an Adjacent DNA Binding Domain Mediate the Formation of Functional cFos-cJun Heterodimers

1989 • 676 citations

The DNA Binding Domain of the Rat Liver Nuclear Protein C/EBP Is Bipartite

1989 • 661 citations

Fos-Associated Protein p39 Is the Product of the jun Proto-Oncogene

1988 • 643 citations

Common DNA binding site for Fos protein complexesand transcription factor AP-1

1988 • 613 citations

Parallel Association of Fos and Jun Leucine Zippers Juxtaposes DNA Binding Domains

1989 • 607 citations

c-JUN, JUN B, and JUN D differ in their binding affinities to AP-1 and CRE consensus sequences: effect of FOS proteins.

1991 • 543 citations

Nuclear factor of activated T cells contains Fos and Jun

1992 • 495 citations

Preferential Heterodimer Formation by Isolated Leucine Zippers from Fos and Jun

1989 • 469 citations

Avian sarcoma virus 17 carries the jun oncogene.

1987 • 445 citations

Folding transition in the DMA-binding domain of GCN4 on specific binding to DNA

1990 • 378 citations

Expression of different Jun and Fos proteins during the G0-to-G1 transition in mouse fibroblasts: in vitro and in vivo associations.

1991 • 309 citations

Fos-Jun heterodimers and jun homodimers bend DNA in opposite orientations: Implications for transcription factor cooperativity

1991 • 296 citations

Design of DNA-Binding Peptides Based on the Leucine Zipper Motif

1990 • 296 citations

Adenovirus DNA replication in vitro.

1979 • 294 citations

Expression and purification of the leucine zipper and DNA-binding domains of Fos and Jun: both Fos and Jun contact DNA directly.

1990 • 245 citations

The Fos Protein Complex Is Associated with DNA in Isolated Nuclei and Binds to DNA Cellulose

1986 • 206 citations

Altered protein conformation on DNA binding by Fos and Jun

1990 • 193 citations

Asymmetrical recognition of the palindromic AP1 binding site (TRE) by Fos protein complexes.

1989 • 191 citations

DNA Bending by Fos and Jun: The Flexible Hinge Model

1991 • 186 citations

Transcriptional regulation by Fos and Jun in vitro: interaction among multiple activator and regulatory domains.

1991 • 175 citations

Selective DNA bending by a variety of bZIP proteins.

1993 • 148 citations

Jun is phosphorylated by several protein kinases at the same sites that are modified in serum-stimulated fibroblasts.

1992 • 123 citations

The Drosophila Fos-related AP-1 protein is a developmentally regulated transcription factor.

1990 • 123 citations

Escape from redox regulation enhances the transforming activity of Fos.

1993 • 119 citations

Nuclear translocation of viral Jun but not of cellular Jun is cell cycle dependent.

1992 • 105 citations

Adaptability at the protein-DNA interface is an important aspect of sequence recognition by bZIP proteins.

1993 • 76 citations

A ubiquitous nuclear protein stimulates the DNA-binding activity of fos and jun indirectly.

1990 • 76 citations

Fos is phosphorylated by p34cdc2, cAMP-dependent protein kinase and protein kinase C at multiple sites clustered within regulatory regions.

1991 • 70 citations

Dimerization and DNA binding alter phosphorylation of Fos and Jun.

1993 • 70 citations

Selective DNA Bending by a Variety of bZIP Proteins

1993 • 58 citations

Common features in DNA recognition helices of eukaryotic transcription factors.

1993 • 56 citations

Jun Is Phosphorylated by Several Protein Kinases at the Same Sites That Are Modified in Serum-Stimulated Fibroblasts

1992 • 39 citations

Mutagenesis of the DNA contact site in Fos protein: compatibility with the scissors grip model and requirement for transformation.

1991 • 21 citations