Adaptability at the protein-DNA interface is an important aspect of sequence recognition by bZIP proteins.

X-Ray Structure of the GCN4 Leucine Zipper, a Two-Stranded, Parallel Coiled Coil

1991 • 1,433 citations

The GCN4 basic region leucine zipper binds DNA as a dimer of uninterrupted α Helices: Crystal structure of the protein-DNA complex

1992 • 964 citations

The DNA Binding Domain of the Rat Liver Nuclear Protein C/EBP Is Bipartite

1989 • 661 citations

DNA RECOGNITION BY PROTEINS WITH THE HELIX-TURN-HELIX MOTIF

1990 • 580 citations

GCN4, a eukaryotic transcriptional activator protein, binds as a dimer to target DNA.

1987 • 395 citations

Folding transition in the DMA-binding domain of GCN4 on specific binding to DNA

1990 • 378 citations

Saturation Mutagenesis of the Yeast his3 Regulatory Site: Requirements for Transcriptional Induction and for Binding by GCN4 Activator Protein

1986 • 352 citations

Defining the Sequence Specificity of DNA-Binding Proteins by Selecting Binding Sites from Random-Sequence Oligonucleotides: Analysis of Yeast GCN4 Protein

1989 • 333 citations

Yeast YAP1 encodes a novel form of the jun family of transcriptional activator proteins.

1989 • 328 citations

Sequence-Specific DNA Binding by a Short Peptide Dimer

1990 • 318 citations

Design of DNA-Binding Peptides Based on the Leucine Zipper Motif

1990 • 296 citations

A family of immunologically related transcription factors that includes multiple forms of ATF and AP-1.

1988 • 259 citations

Cognate DNA Binding Specificity Retained After Leucine Zipper Exchange Between GCN4 and C/EBP

1989 • 237 citations

Altered protein conformation on DNA binding by Fos and Jun

1990 • 193 citations

Mutations That Define the Optimal Half-Site for Binding Yeast GCN4 Activator Protein and Identify an ATF/CREB-Like Repressor That Recognizes Similar DNA Sites

1990 • 100 citations

ACR1, a yeast ATF/CREB repressor.

1992 • 82 citations

The leucine zipper symmetrically positions the adjacent basic regions for specific DNA binding.

1991 • 75 citations

Highly conserved residues in the bZIP domain of yeast GCN4 are not essential for DNA binding.

1991 • 49 citations

Mutations in the bZIP domain of yeast GCN4 that alter DNA-binding specificity.

1992 • 28 citations

ACR1, a Yeast ATF/CREB Repressor

1992 • 24 citations

Highly Conserved Residues in the bZIP Domain of Yeast GCN4 Are Not Essential for DNA Binding

1991 • 15 citations