Distinct Monocyte Gene-Expression Profiles in Autoimmune Diabetes

Statistical methods

1967 • 19,533 citations

Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus

2002 • 10,002 citations

Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus

1997 • 6,073 citations

CYCLOOXYGENASES 1 AND 2

1998 • 2,700 citations

Inflammation and Activated Innate Immunity in the Pathogenesis of Type 2 Diabetes

2004 • 1,361 citations

The macrophage theory of depression

1991 • 871 citations

Anti-inflammatory and immunomodulatory potential of the novel PDE4 inhibitor roflumilast in vitro.

2001 • 382 citations

Induction of the cyclic nucleotide phosphodiesterase PDE4B is essential for LPS-activated TNF-α responses

2002 • 356 citations

A Discriminating Messenger RNA Signature for Bipolar Disorder Formed by an Aberrant Expression of Inflammatory Genes in Monocytes

2008 • 332 citations

The immune system, depression and the action of antidepressants

2001 • 330 citations

Increased Monocytic Activity and Biomarkers of Inflammation in Patients With Type 1 Diabetes

2006 • 286 citations

Gene Expression in Peripheral Blood Mononuclear Cells from Children with Diabetes

2007 • 202 citations

In vitro differentiation of human monocytes to macrophages: change of PDE profile and its relationship to suppression of tumour necrosis factor‐α release by PDE inhibitors

1997 • 143 citations

Impaired Yield, Phenotype, and Function of Monocyte-Derived Dendritic Cells in Humans at Risk for Insulin-Dependent Diabetes

1998 • 140 citations

Increased Serum Levels of MRP-8/14 in Type 1 Diabetes Induce an Increased Expression of CD11b and an Enhanced Adhesion of Circulating Monocytes to Fibronectin

2004 • 113 citations

Protective Molecules–C-Reactive Protein (CRP), Serum Amyloid P (SAP), Pentraxin3 (PTX3), Mannose-Binding Lectin (MBL), and Apolipoprotein A1 (Apo A1), and Their Autoantibodies: Prevalence and Clinical Significance in Autoimmunity

2005 • 111 citations

Identification of a Molecular Signature in Human Type 1 Diabetes Mellitus Using Serum and Functional Genomics

2008 • 110 citations

Phosphodiesterase 4 inhibitors, structurally unrelated to Rolipram, as promising agents for the treatment of asthma and other pathologies

2000 • 108 citations

Microarray analysis of human leucocyte subsets: the advantages of positive selection and rapid purification

2007 • 107 citations

A high prevalence of organ-specific autoimmunity in patients with bipolar disorder

2004 • 101 citations

The Phosphodiesterase Inhibitors Pentoxifylline and Rolipram Suppress Macrophage Activation and Nitric Oxide Production in Vitro and in Vivo

2001 • 82 citations

The phosphodiesterase inhibitors pentoxifylline and rolipram prevent diabetes in NOD mice.

1998 • 72 citations

Age-Dependent Influences on the Origins of Autoimmune Diabetes

2004 • 72 citations

Macrophages from High‐Risk HLA‐DQB1*0201/*0302 Type 1 Diabetes Mellitus Patients are Hypersensitive to Lipopolysaccharide Stimulation

2002 • 42 citations

Poor In Vitro Maturation and Pro‐Inflammatory Cytokine Response of Dendritic Cells in Children at Genetic Risk of Type 1 Diabetes

2004 • 30 citations

High glucose‐boosted inflammatory responses to lipopolysaccharide are suppressed by statin

2006 • 28 citations

Aberrant monocyte prostaglandin synthase 2 (PGS2) expression in type 1 diabetes before and after disease onset

2003 • 27 citations

Altered Monocyte Cyclooxygenase Response to Lipopolysaccharide in Type 1 Diabetes

2006 • 27 citations

Characterization of Monocyte-Derived Dendritic Cells in Recent-Onset Diabetes Mellitus Type 1

2002 • 21 citations