Saturated FFAs, Palmitic Acid and Stearic Acid, Induce Apoptosis in Human Granulosa Cells

Adipose Expression of Tumor Necrosis Factor-α: Direct Role in Obesity-Linked Insulin Resistance

1993 • 7,219 citations

Peroxisome Proliferator-Activated Receptors: Nuclear Control of Metabolism*

1999 • 2,880 citations

Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis

1994 • 2,450 citations

Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis

1994 • 1,969 citations

Role of Fatty Acids in the Pathogenesis of Insulin Resistance and NIDDM

1997 • 1,611 citations

Pathophysiologic Implications of Membrane Phospholipid Asymmetry in Blood Cells

1997 • 1,321 citations

Tumor necrosis factor alpha inhibits signaling from the insulin receptor.

1994 • 1,173 citations

Fatty acid-induced β cell apoptosis: A link between obesity and diabetes

1998 • 1,142 citations

Effect of fatty acids on glucose production and utilization in man.

1983 • 1,056 citations

Ceramide synthase mediates daunorubicin-induced apoptosis: An alternative mechanism for generating death signals

1995 • 835 citations

Glucose and free fatty acid metabolism in non-insulin-dependent diabetes mellitus. Evidence for multiple sites of insulin resistance.

1989 • 799 citations

Modulation of Insulin Activities by Leptin

1996 • 733 citations

Measurement of Plasma Glucose, Free Fatty Acid, Lactate, and Insulin for 24 h in Patients With NIDDM

1988 • 713 citations

Mechanisms of phosphatidylserine exposure, a phagocyte recognition signal, on apoptotic T lymphocytes.

1995 • 675 citations

Establishment and Characterization of a Steroidogenic Human Granulosa-Like Tumor Cell Line, KGN, That Expresses Functional Follicle-Stimulating Hormone Receptor

2001 • 490 citations

Role of plasmalemmal caveolae in signal transduction

1998 • 466 citations

Cellular uptake and intracellular trafficking of long chain fatty acids

1999 • 380 citations

Fumonisin B1 inhibits sphingosine (sphinganine) N-acyltransferase and de novo sphingolipid biosynthesis in cultured neurons in situ.

1993 • 363 citations

Expression of members of the bcl-2 gene family in the immature rat ovary: equine chorionic gonadotropin-mediated inhibition of granulosa cell apoptosis is associated with decreased bax and constitutive bcl-2 and bcl-xlong messenger ribonucleic acid levels.

1995 • 356 citations

Prostaglandins: Members of a New Hormonal System

1967 • 347 citations

The Adipose Obese Gene Product, Leptin: Evidence of a Direct Inhibitory Role in Ovarian Function*

1997 • 328 citations

Skeletal muscle membrane lipid composition is related to adiposity and insulin action.

1995 • 312 citations

pH gradients across phospholipid membranes caused by fast flip-flop of un-ionized fatty acids.

1992 • 293 citations

Protection against lipoapoptosis of β cells through leptin-dependent maintenance of Bcl-2 expression

1998 • 211 citations

Fas Antigen-Mediated Apoptosis in Human Granulosa/luteal Cells1

1995 • 187 citations

Insulin resistance directly correlates with increased saturated fatty acids in skeletal muscle triglycerides

2000 • 169 citations

Postprandial hyperinsulinemia in patients with mild essential hypertension.

1985 • 166 citations

Physiological Modulation of Plasma Free Fatty Acid Concentrations by Diet: Metabolic implications in nondiabetic subjects

1995 • 140 citations

Acylglycerol Recycling from Triacylglycerol to Phospholipid, Not Lipase Activity, Is Defective in Neutral Lipid Storage Disease Fibroblasts

1996 • 133 citations

Analysis of apoptosis and expression of bcl-2 gene family members in the human and baboon ovary

1998 • 130 citations

Insulin Signaling and Action in Fat Cells: Associations with Insulin Resistance and Type 2 Diabetes

1999 • 111 citations

Involvement of p53 Expression in cAMP-Mediated Apoptosis in Immortalized Granulosa Cells

1995 • 103 citations

Immunological evidence for the expression of the Fas antigen in the infant and adult human ovary during follicular regression and atresia.

1996 • 90 citations

Hypertriglyceridemia and its Metabolic Consequences as a Risk Factor for Atherosclerotic Cardiovascular Disease in Non-Insulin-Dependent Diabetes Mellitus

1996 • 83 citations

Insulin Resistance in Obesity: Metabolic Mechanisms and Measurement Methods

1998 • 80 citations

Selective inhibition of inducible nitric oxide synthase by aminoguanidine

1996 • 77 citations

Randomized placebo-controlled study of the effects of simvastatin on haemostatic variables, lipoproteins and free fatty acids

1997 • 74 citations

Engineering of Glycerol-stimulated Insulin Secretion in Islet Beta Cells

1997 • 74 citations

Crosstalk Among Multiple Signaling Pathways Controlling Ovarian Cell Death

1999 • 73 citations

Postprandial lipid and hormone responses to meals of varying fat contents: modulatory role of lipoprotein lipase?

1995 • 73 citations

Glucose and free fatty acid turnover in normal subjects and in diabetic patients before and after insulin treatment

1979 • 73 citations

Changes in internal pH caused by movement of fatty acids into and out of clonal pancreatic beta-cells (HIT).

1994 • 71 citations

Thiazolidinedione Induces Apoptosis and Monocytic Differentiation in the Promyelocytic Leukemia Cell Line HL60

1999 • 63 citations

Suppression of W256 carcinosarcoma cell apoptosis by arachidonic acid and other polyunsaturated fatty acids

1997 • 57 citations

Endocrine Comparison of Obese Menstruating and Amenorrheic Women*

1984 • 57 citations

Ethanol and arachidonic acid produce toxicity in hepatocytes from pyrazole-treated rats with high levels of CYP2E1.

2000 • 56 citations

Apoptosis in human primary brain tumours: actions of arachidonic acid

1998 • 55 citations

Modulation of human granulosa cell steroid production in vitro by tumor necrosis factor alpha: implications of white blood cells in culture.

1994 • 53 citations

Suppression of W256 carcinosarcoma cell apoptosis by arachidonic acid and other polyunsaturated fatty acids

1997 • 52 citations

Elevated serum free fatty acid concentrations inhibit T lymphocyte signaling

2000 • 51 citations

Regulation of Nitric Oxide Synthase to Promote Cytostasis in Ovarian Follicular Development1

2000 • 47 citations

Sphingolipid Regulation of Female Gonadal Cell Apoptosis

2000 • 39 citations

Secondary Amenorrhea in Obesity: Etiologic Role of Weight-Related Androgen Excess

1978 • 38 citations

Evidence for an Inverse Relationship between Apoptosis and Inducible Nitric Oxide Synthase Expression in Rat Granulosa Cells: A Possible Role of Nitric Oxide in Ovarian Follicle Atresia.

1998 • 38 citations

Comparison of the Reactivity of Tetradecenoic Acids, a Triacsin, and Unsaturated Oximes with Four Purified Saccharomyces cerevisiae Fatty Acid Activation Proteins

1995 • 38 citations

Altered androstenedione and estrone dynamics associated with abnormal hormonal profiles in amenorrheic subjects with weight loss or obesity

1985 • 23 citations

Synthesis of 4- and 5-series leukotrienes in the lung microvasculature challenged with Escherichia coli hemolysin: critical dependence on exogenous free fatty acid supply.

1997 • 22 citations

Kinetics of Free Fatty Acids in Hypertriglyceridemia

1993 • 10 citations

Involvement of membrane surface charge in thermal stability of the rat ovarian LH/hCG receptor

2000 • 5 citations