Functional Activity of the Fanconi Anemia Protein FAA Requires FAC Binding and Nuclear Localization

The Metabolic and Molecular Bases of Inherited Disease

1995 • 12,086 citations

Nuclear targeting sequences — a consensus?

1991 • 1,908 citations

Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: Identification of a class of bipartite nuclear targeting sequence

1991 • 1,501 citations

Association of BRCA1 with Rad51 in Mitotic and Meiotic Cells

1997 • 1,466 citations

The hMre11/hRad50 Protein Complex and Nijmegen Breakage Syndrome: Linkage of Double-Strand Break Repair to the Cellular DNA Damage Response

1998 • 1,220 citations

Nibrin, a Novel DNA Double-Strand Break Repair Protein, Is Mutated in Nijmegen Breakage Syndrome

1998 • 1,071 citations

A stable human-derived packaging cell line for production of high titer retrovirus/vesicular stomatitis virus G pseudotypes.

1996 • 925 citations

Dynamic Changes of BRCA1 Subnuclear Location and Phosphorylation State Are Initiated by DNA Damage

1997 • 910 citations

The role of phosphorylation and the CDC28 protein kinase in cell cycle-regulated nuclear import of the S. cerevisiae transcription factor SW15

1991 • 501 citations

Expression cloning of a cDNA for the major Fanconi anaemia gene, FAA

1996 • 411 citations

Positional cloning of the Fanconi anaemia group A gene

1996 • 295 citations

Evidence for at Least Eight Fanconi Anemia Genes

1997 • 292 citations

Germ cell defects and hematopoietic hypersensitivity to gamma- interferon in mice with a targeted disruption of the Fanconi anemia C gene

1996 • 265 citations

Inactivation of Fac in mice produces inducible chromosomal instability and reduced fertility reminiscent of Fanconi anaemia

1996 • 261 citations

Germ cell defects and hematopoietic hypersensitivity to gamma- interferon in mice with a targeted disruption of the Fanconi anemia C gene

1996 • 233 citations

The Fanconi anaemia proteins, FAA and FAC interact to form a nuclear complex

1997 • 207 citations

Molecular Biology of Fanconi Anemia: Implications for Diagnosis and Therapy

1997 • 207 citations

The Nuclear Localization Sequences of the BRCA1 Protein Interact with the Importin-α Subunit of the Nuclear Transport Signal Receptor

1996 • 204 citations

Classification of Fanconi anemia patients by complementation analysis: evidence for a fifth genetic subtype

1995 • 183 citations

Inactivation of the Fanconi Anemia Group C Gene Augments Interferon-γ–Induced Apoptotic Responses in Hematopoietic Cells

1997 • 177 citations

Fanconi anemia and novel strategies for therapy

1994 • 148 citations

The Fanconi anemia polypeptide FACC is localized to the cytoplasm.

1994 • 147 citations

Localization of Fanconi anemia C protein to the cytoplasm of mammalian cells.

1994 • 142 citations

Nuclear import of U snRNPs requires importin beta

1997 • 141 citations

BRCA1, BRCA2, and DNA Damage Response: Collision or Collusion?

1998 • 137 citations

Sequence variation in the Fanconi anemia gene FAA

1997 • 123 citations

The Fanconi Anemia Polypeptide, FAC, Binds to the Cyclin-Dependent Kinase, cdc2

1997 • 108 citations

Flow cytometric characterization of the response of Fanconi's anemia cells to mitomycin C treatment

1982 • 96 citations

The Fanconi Anemia Group C Gene Product Is Located in Both the Nucleus and Cytoplasm of Human Cells

1998 • 95 citations

Endogenous blockage and delay of the chromosome cycle despite normal recruitment and growth phase explain poor proliferation and frequent edomitosis in Fanconi anemia cells.

1985 • 89 citations

Suppression of apoptosis in hematopoietic factor-dependent progenitor cell lines by expression of the FAC gene

1996 • 89 citations

Bone Marrow Failure in the Fanconi Anemia Group C Mouse Model After DNA Damage

1998 • 86 citations

Complementation groups: one or more per gene?

1995 • 85 citations

Deregulated apoptosis is a hallmark of the Fanconi anemia syndrome.

1997 • 80 citations

The Fanconi anemia complementation group C protein corrects DNA interstrand cross-link-specific apoptosis in HSC536N cells

1996 • 40 citations

Cytoplasmic Localization of a Functionally Active Fanconi Anemia Group A–Green Fluorescent Protein Chimera in Human 293 Cells

1997 • 39 citations

Cytogenetic and flow cytometric studies of cells from patients with Fanconi’s anemia

1982 • 27 citations

Fanconi's anemia: what have we learned from the genes so far?

1998 • 8 citations