Mutations in Multidrug Efflux Homologs, Sugar Isomerases, and Antimicrobial Biosynthesis Genes Differentially Elevate Activity of the ς ^X and ς ^W Factors in Bacillus subtilis

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

1997 • 71,835 citations

Experiments in molecular genetics

1972 • 28,260 citations

The complete genome sequence of the Gram-positive bacterium Bacillus subtilis

1997 • 3,613 citations

Tmbase-A database of membrane spanning protein segments

1993 • 2,294 citations

Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells

1986 • 1,903 citations

Molecular biological methods for Bacillus

1990 • 1,454 citations

Expert system for predicting protein localization sites in gram‐negative bacteria

1991 • 739 citations

A vector for systematic gene inactivation in Bacillus subtilis

1998 • 651 citations

Characterization of Sfp, a Bacillus subtilis Phosphopantetheinyl Transferase for Peptidyl Carrier Protein Domains in Peptide Synthetases

1998 • 632 citations

The sigma factors of Bacillus subtilis

1995 • 537 citations

Analysis of the Streptomyces coelicolor sigE gene reveals the existence of a subfamily of eubacterial RNA polymerase sigma factors involved in the regulation of extracytoplasmic functions.

1994 • 486 citations

Nucleotide sequence and characterization of the Staphylococcus aureus norA gene, which confers resistance to quinolones

1990 • 479 citations

Evidence that the Extracytoplasmic Function Sigma Factor ς ^E Is Required for Normal Cell Wall Structure in Streptomyces coelicolor A3(2)

1999 • 395 citations

Identification of a genetic locus required for biosynthesis of the lipopeptide antibiotic surfactin in Bacillus subtilis

1988 • 313 citations

Sequence and analysis of the genetic locus responsible for surfactin synthesis in Bacillus subtilis

1993 • 296 citations

The sigma(E) and the Cpx signal transduction systems control the synthesis of periplasmic protein-folding enzymes in Escherichia coli.

1997 • 273 citations

An Exported Peptide Functions Intracellularly to Contribute to Cell Density Signaling in B. subtilis

1997 • 242 citations

Cloning, nucleotide sequence, and characterization of genes encoding the secretion function of the Pasteurella haemolytica leukotoxin determinant

1989 • 239 citations

The spo0K locus of Bacillus subtilis is homologous to the oligopeptide permease locus and is required for sporulation and competence

1991 • 237 citations

Characterization of the inducible nickel and cobalt resistance determinant cnr from pMOL28 of Alcaligenes eutrophus CH34

1993 • 223 citations

Isolation of a prokaryotic metallothionein locus and analysis of transcriptional control by trace metal ions

1993 • 214 citations

Subtilist: a relational database for the Bacillus subtilis genome

1995 • 202 citations

sigma R, an RNA polymerase sigma factor that modulates expression of the thioredoxin system in response to oxidative stress in Streptomyces coelicolor A3(2)

1998 • 201 citations

The Sialic Acids

1971 • 198 citations

Inventory, assembly and analysis of Bacillus subtilis ABC transport systems

1999 • 186 citations

Metalloregulated expression of the ars operon.

1993 • 181 citations

Expression and regulation of the antimonite, arsenite, and arsenate resistance operon of Staphylococcus xylosus plasmid pSX267

1992 • 177 citations

CadC, the transcriptional regulatory protein of the cadmium resistance system of Staphylococcus aureus plasmid pI258

1995 • 175 citations

Identification of a putative metal binding site in a new family of metalloregulatory proteins.

1994 • 173 citations

Two highly similar multidrug transporters of Bacillus subtilis whose expression is differentially regulated

1995 • 171 citations

An SmtB-like repressor from Synechocystis PCC 6803 regulates a zinc exporter

1998 • 169 citations

The algT (algU) gene of Pseudomonas aeruginosa, a key regulator involved in alginate biosynthesis, encodes an alternative sigma factor (sigma E).

1995 • 166 citations

Identification of comS, a gene of the srfA operon that regulates the establishment of genetic competence in Bacillus subtilis.

1994 • 152 citations

Molecular analyses of the lactococcin A gene cluster from Lactococcus lactis subsp. lactis biovar diacetylactis WM4

1992 • 151 citations

Mutation of the Bacillus subtilis alkyl hydroperoxide reductase (ahpCF) operon reveals compensatory interactions among hydrogen peroxide stress genes

1996 • 142 citations

Easy cloning of mini-Tn10 insertions from the Bacillus subtilis chromosome

1994 • 139 citations

Exotoxin A production in Pseudomonas aeruginosa requires the iron‐regulated pvdS gene encoding an alternative sigma factor

1996 • 135 citations

Metalloregulation in Bacillus subtilis: isolation and characterization of two genes differentially repressed by metal ions

1993 • 130 citations

Mandelate racemase and muconate lactonizing enzyme are mechanistically distinct and structurally homologous

1990 • 128 citations

Magnesium transport in Salmonella typhimurium: the influence of new mutations conferring Co²⁺ resistance on the CorA Mg²⁺ transport system

1991 • 127 citations

Novel phosphotransferase system genes revealed by genome analysis – the complete complement of PTS proteins encoded within the genome of Bacillus subtilis

1999 • 127 citations

The Genes degQ , pps , and lpa-8 ( sfp ) Are Responsible for Conversion of Bacillus subtilis 168 to Plipastatin Production

1999 • 126 citations

Identification of target promoters for the Bacillus subtilis extracytoplasmic function σ factor, σ^W

1999 • 123 citations

Promoter Recognition by Bacillus subtilis ς ^W : Autoregulation and Partial Overlap with the ς ^X Regulon

1998 • 115 citations

Molecular analysis of the phoH gene, belonging to the phosphate regulon in Escherichia coli

1993 • 114 citations

Identification of ς ^B -Dependent Genes in Bacillus subtilis Using a Promoter Consensus-Directed Search and Oligonucleotide Hybridization

1999 • 112 citations

Identification of target promoters for the Bacillus subtilis σ X factor using a consensus-directed search 1 1Edited by R. Ebright

1998 • 110 citations

σ^M, an ECF RNA polymerase sigma factor of Bacillus subtilis 168, is essential for growth and survival in high concentrations of salt

1999 • 110 citations

Cloning and Sequencing of a Novel meta -Cleavage Dioxygenase Gene Whose Product Is Involved in Degradation of γ-Hexachlorocyclohexane in Sphingomonas paucimobilis

1999 • 109 citations

Difficidin and oxydifficidin: Novel broad spectrum antibacterial antibiotics produced by Bacillus subtilis. I.Production, taxonomy and antibacterial activity.

1987 • 105 citations

Transcriptional regulation of ferric citrate transport in Escherichia coli K‐12. Fecl belongs to a new subfamily of σ⁷⁰‐type factors that respond to extracytoplasmic stimuli

1995 • 105 citations

Mutations that relieve nutritional repression of the Bacillus subtilis dipeptide permease operon

1993 • 97 citations

Involvement of Superoxide Dismutase in Spore Coat Assembly in Bacillus subtilis

1998 • 95 citations

Sequencing and characterization of a gene cluster encoding the enzymes for L-rhamnose metabolism in Escherichia coli

1993 • 95 citations

The Bacillus subtilis sigma(X) protein is an extracytoplasmic function sigma factor contributing to survival at high temperature

1997 • 89 citations

Sequence completion, identification and definition of the fengycin operon in Bacillus subtilis 168

1997 • 75 citations

PcpA, which is involved in the degradation of pentachlorophenol in Sphingomonas chlorophenolica ATCC39723, is a novel type of ring‐cleavage dioxygenase

1999 • 69 citations

Identification, expression, and DNA sequence of the GDP-mannose biosynthesis genes encoded by the O7 rfb gene cluster of strain VW187 (Escherichia coli O7:K1)

1993 • 63 citations

Identification and Molecular Analysis of the Gene Encoding Rickettsia typhi Hemolysin

1999 • 55 citations

The Sialic Acids

1965 • 53 citations

Analysis of Genes Involved in Biosynthesis of Coronafacic Acid, the Polyketide Component of the Phytotoxin Coronatine

1998 • 53 citations

Role of Crotonyl Coenzyme A Reductase in Determining the Ratio of Polyketides Monensin A and Monensin B Produced by Streptomyces cinnamonensis

1999 • 48 citations

Sigma‐E is required for the production of the antibiotic actinomycin in Streptomyces antibioticus

1997 • 40 citations

Bacillus subtilis operon under the dual control of the general stress transcription factor σ^B and the sporulation transcription factor σ^H

1996 • 34 citations

Characterization of ylbF, a new gene involved in competence development and sporulation in Bacillus subtilis

2000 • 34 citations

Bacillus subtilis mutS mutL operon: identification, nucleotide sequence and mutagenesis

1996 • 32 citations

Molecular characterization of the operon comprising the spoIV gene of Bacillus megaterium DSM319 and generation of a deletion mutant.

1998 • 23 citations

Complete structure of the adhesin receptor polysaccharide of Streptococcus oralis ATCC 55229 (Streptococcus sanguis H1)

1992 • 20 citations

Isolation and sequence analysis of the pmi gene encoding phosphomannose isomerase of Streptococcus mutans

1993 • 9 citations