sigma R, an RNA polymerase sigma factor that modulates expression of the thioredoxin system in response to oxidative stress in Streptomyces coelicolor A3(2)

Free radicals in biology and medicine

1991 • 17,840 citations

Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence

1998 • 7,572 citations

Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes

1986 • 6,284 citations

Oxidized Redox State of Glutathione in the Endoplasmic Reticulum

1992 • 1,909 citations

Genetic manipulation of Streptomyces : a laboratory manual

1985 • 1,765 citations

Activation of the OxyR Transcription Factor by Reversible Disulfide Bond Formation

1998 • 1,162 citations

Oxidative stress and the molecular biology of antioxidant defenses.

1997 • 1,031 citations

Positive control of a regulon for defenses against oxidative stress and some heat-shock proteins in Salmonella typhimurium

1985 • 1,025 citations

Transcriptional Regulator of Oxidative Stress-Inducible Genes: Direct Activation by Oxidation

1990 • 869 citations

The Role of the Thioredoxin and Glutaredoxin Pathways in Reducing Protein Disulfide Bonds in the Escherichia coliCytoplasm

1997 • 637 citations

Intracellular production of superoxide radical and of hydrogen peroxide by redox active compounds

1979 • 595 citations

A set of ordered cosmids and a detailed genetic and physical map for the 8 Mb Streptomyces coelicolor A3(2) chromosome

1996 • 530 citations

Distribution of thiols in microorganisms: mycothiol is a major thiol in most actinomycetes

1996 • 510 citations

Analysis of the Streptomyces coelicolor sigE gene reveals the existence of a subfamily of eubacterial RNA polymerase sigma factors involved in the regulation of extracytoplasmic functions.

1994 • 486 citations

Mutations that Allow Disulfide Bond Formation in the Cytoplasm of Escherichia coli

1993 • 420 citations

[11] Diamide: An oxidant probe for thiols

1995 • 333 citations

Reduction of disulfides by thioredoxin. Exceptional reactivity of insulin and suggested functions of thioredoxin in mechanism of hormone action.

1979 • 324 citations

Bovine thioredoxin system. Purification of thioredoxin reductase from calf liver and thymus and studies of its function in disulfide reduction.

1977 • 294 citations

Dispersed growth of Streptomyces in liquid culture

1989 • 272 citations

The ppGpp synthetase gene (relA) of Streptomyces coelicolor A3(2) plays a conditional role in antibiotic production and morphological differentiation

1997 • 216 citations

A glutathione reductase mutant of yeast accumulates high levels of oxidized glutathione and requires thioredoxin for growth.

1996 • 188 citations

Complex organization of the Streptomyces avermitilis genes encoding the avermectin polyketide synthase

1992 • 182 citations

Thioredoxin Is an Essential Protein Induced by Multiple Stresses in Bacillus subtilis

1998 • 162 citations

Cloning, disruption, and transcriptional analysis of three RNA polymerase sigma factor genes of Streptomyces coelicolor A3(2)

1990 • 155 citations

At least three different RNA polymerase holoenzymes direct transcription of the agarase gene (dagA) of streptomyces coelicolor A3(2)

1988 • 145 citations

NADPH: ferredoxin oxidoreductase acts as a paraquatdiaphorase and is a member of the soxRS regulon.

1994 • 142 citations

Differential Expression of Superoxide Dismutases Containing Ni and Fe/Zn in Streptomyces Coelicolor

1996 • 138 citations

Substrate induction and catabolite repression of the Streptomyces coelicoior glycerol operon are mediated through the GyIR protein

1994 • 95 citations

Identification of sigma factors for growth phase-related promoter selectivity of RNA polymerases from Streptomyces coelicolor A3(2)

1997 • 93 citations

Gene disruption and gene replacement inStreptomycesvia single stranded DNA transformation of integration vectors

1991 • 90 citations

Isolation and characterization of the major vegetative RNA polymerase of Streptomyces coelicolor A3(2); renaturation of a sigma subunit using GroEL

1992 • 84 citations

The Levels of Ribonucleotide Reductase, Thioredoxin, Glutaredoxin 1, and GSH Are Balanced in Escherichia coli K12

1996 • 63 citations

oxyR-dependent induction of Escherichia coli grx gene expression by peroxide stress

1997 • 43 citations

Increased intracellular survival of Mycobacterium smegmatis containing the Mycobacterium leprae thioredoxin-thioredoxin reductase gene

1997 • 42 citations

Sigma‐E is required for the production of the antibiotic actinomycin in Streptomyces antibioticus

1997 • 40 citations

Construction and application of streptomycete promoter probe vectors which employ the Streptomyces glaucescens tyrosinase-encoding gene as reporter

1994 • 37 citations

Thioredoxin-thioredoxin reductase system of Streptomyces clavuligerus: sequences, expression, and organization of the genes

1993 • 33 citations

Characterization of a broad-range disulfide reductase from Streptomyces clavuligerus and its possible role in beta-lactam antibiotic biosynthesis

1993 • 31 citations

Transcriptional Regulators of Oxidative Stress Responses

1997 • 30 citations