Effect of Aging and Diabetes on the Enteroinsular Axis

Prevalence of Diabetes, Impaired Fasting Glucose, and Impaired Glucose Tolerance in U.S. Adults: The Third National Health and Nutrition Examination Survey, 1988–1994

1998 • 2,780 citations

Dipeptidyl‐peptidase IV hydrolyses gastric inhibitory polypeptide, glucagon‐like peptide‐1(7–36)amide, peptide histidine methionine and is responsible for their degradation in human serum

1993 • 1,119 citations

Degradation of glucose-dependent insulinotropic polypeptide and truncated glucagon-like peptide 1 in vitro and in vivo by dipeptidyl peptidase IV.

1995 • 1,064 citations

Inhibition of the activity of dipeptidyl-peptidase IV as a treatment for type 2 diabetes.

1998 • 480 citations

The insulinotropic actions of glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (7–37) in normal and diabetic subjects

1994 • 309 citations

Degradation of glucose-dependent insulinotropic polypeptide and truncated glucagon-like peptide 1 in vitro and in vivo by dipeptidyl peptidase IV

1995 • 283 citations

Improved Glucose Tolerance in Zucker Fatty Rats by Oral Administration of the Dipeptidyl Peptidase IV Inhibitor Isoleucine Thiazolidide

1998 • 260 citations

Effects of age on concentrations of plasma cholecystokinin, glucagon-like peptide 1, and peptide YY and their relation to appetite and pyloric motility

1999 • 245 citations

Different aetiologies of Type 2 (non-insulin-dependent) diabetes mellitus in obese and non-obese subjects

1991 • 187 citations

Counterregulatory Hormone Responses to Hypoglycemia in the Elderly Patient with Diabetes

1994 • 161 citations

Investigation of Glucose-dependent Insulinotropic Polypeptide(1-42) and Glucagon-like Peptide-1-(7-36) Degradation by Dipeptidyl Peptidase IV Using Matrix-assisted Laser Desorption/Ionization-Time of Flight Mass Spectrometry

1996 • 153 citations

Dipeptidyl Peptidase IV from Human Serum: Purification, Characterization, and N-Terminal Amino Acid Sequence

1998 • 123 citations

Metabolic alterations in middle-aged and elderly obese patients with type 2 diabetes.

1999 • 123 citations

A Novel Form of Dipeptidylpeptidase IV Found in Human Serum.

1995 • 118 citations

Altered responses to hypoglycemia of healthy elderly people.

1994 • 109 citations

Immunoreactive Gastric Inhibitory Polypeptide*

1988 • 96 citations

Serum high molecular weight dipeptidyl peptidase IV (CD26) is similar to a novel antigen DPPT-L released from activated T cells.

1996 • 90 citations

Increased Disorderliness of Basal Insulin Release, Attenuated Insulin Secretory Burst Mass, and Reduced Ultradian Rhythmicity of Insulin Secretion in Older Individuals1

1997 • 85 citations

The Enteric Enhancement of Glucose-stimulated Insulin Release: The Role of GIP in Aging, Obesity, and Non-insulin-dependent Diabetes Mellitus

1984 • 83 citations

The Incretin Notion and its Relevance to Diabetes

1993 • 82 citations

NIDDM in the elderly

1996 • 79 citations

Effect of Age on Fasting Plasma Levels of Pancreatic Hormones in Man*

1978 • 73 citations

Insulin and glucagon relationships during aging in man

1977 • 68 citations

Improved glucose tolerance in Zucker fatty rats by oral administration of the dipeptidyl peptidase IV inhibitor isoleucine thiazolidide

1998 • 67 citations

Attenuated Glucose Recovery from Hypoglycemia in the Elderly

1992 • 62 citations

The ageing entero-insular axis

1998 • 54 citations

The enteroinsular axis in dipeptidyl peptidase IV-negative rats

1996 • 52 citations

Altered responses to hypoglycemia of healthy elderly people

1994 • 48 citations

The Effect of Glyburide on β-Cell Sensitivity to Glucose-Dependent Insulinotropic Polypeptide

1993 • 40 citations

The Effect of Age and Glycemic Level on the Response of theβ -Cell to Glucose-Dependent Insulinotropic Polypeptide and Peripheral Tissue Sensitivity to Endogenously Released Insulin1

1998 • 38 citations

Counterregulatory hormone responses to hypoglycemia in the elderly patient with diabetes

1994 • 32 citations

Increased Disorderliness of Basal Insulin Release, Attenuated Insulin Secretory Burst Mass, and Reduced Ultradian Rhythmicity of Insulin Secretion in Older Individuals

1997 • 31 citations

Glucagon physiology and aging: Evidence for enhanced hepatic sensitivity

1983 • 30 citations

The enteric enhancement of glucose-stimulated insulin release. The role of GIP in aging, obesity, and non-insulin-dependent diabetes mellitus

1984 • 29 citations

Dipeptidyl‐peptidase IV‐β

1998 • 27 citations

THE EFFECT OF AGE AND SEX ON THE RESPONSE OF ENTEROPANCREATIC POLYPEPTIDES TO ORAL GLUCOSE

1983 • 27 citations

Human serum dipeptidyl peptidase IV (DPPIV) and its unique properties

1996 • 25 citations

[Catalytic mechanism of dipeptidyl-peptidase IV].

1978 • 18 citations

The Effect of Age and Glycemic Level on the Response of the -Cell to Glucose-Dependent Insulinotropic Polypeptide and Peripheral Tissue Sensitivity to Endogenously Released Insulin

1998 • 11 citations

Attenuated glucose recovery from hypoglycemia in the elderly

1992 • 10 citations