Evidence for a physical interaction between the Escherichia coli methyl-directed mismatch repair proteins MutL and UvrD

Experiments in molecular genetics

1972 • 28,260 citations

Current protocols in molecular biology

1988 • 7,584 citations

MISMATCH REPAIR IN REPLICATION FIDELITY, GENETIC RECOMBINATION, AND CANCER BIOLOGY

1996 • 1,485 citations

DNA EXCISION REPAIR

1996 • 1,127 citations

Biochemistry and genetics of eukaryotic mismatch repair.

1996 • 598 citations

DNA Mismatch Correction in a Defined System

1989 • 551 citations

Genetic analysis of the recF pathway to genetic recombination in Escherichia coli k12: Isolation and characterization of mutants

1973 • 479 citations

Escherichia coli mutator mutants deficient in methylation-instructed DNA mismatch correction.

1980 • 391 citations

Escherichia coli mutS-encoded protein binds to mismatched DNA base pairs.

1986 • 353 citations

Methyl-directed repair of DNA base-pair mismatches in vitro.

1983 • 344 citations

Mispair specificity of methyl-directed DNA mismatch correction in vitro.

1988 • 341 citations

MutS mediates heteroduplex loop formation by a translocation mechanism

1997 • 325 citations

Identification of mismatch repair genes and their role in the development of cancer

1995 • 319 citations

Initiation of methyl-directed mismatch repair.

1992 • 313 citations

DNA damage tolerance, mismatch repair and genome instability

1994 • 308 citations

Isolation and Characterization of the Escherichia coli mutL Gene Product

1989 • 298 citations

EFFECTS OF HIGH LEVELS OF DNA ADENINE METHYLATION ON METHYL-DIRECTED MISMATCH REPAIR IN ESCHERICHIA COLI

1983 • 294 citations

Microsatellite instability in inherited and sporadic neoplasms

1995 • 257 citations

Effect of DNA polymerase I and DNA helicase II on the turnover rate of UvrABC excision nuclease.

1985 • 223 citations

Involvement of helicase II (uvrD gene product) and DNA polymerase I in excision mediated by the uvrABC protein complex.

1985 • 222 citations

Dual requirement in yeast DNA mismatch repair for MLH1 and PMS1, two homologs of the bacterial mutL gene.

1994 • 222 citations

Escherichia coli helicase II (urvD gene product) translocates unidirectionally in a 3' to 5' direction.

1986 • 212 citations

DNA‐replication Fidelity, Mismatch Repair and Genome Instability in Cancer Cells

1996 • 209 citations

Methyl-directed mismatch repair is bidirectional

1993 • 208 citations

Cloning and nucleotide sequence of DNA mismatch repair gene PMS1 from Saccharomyces cerevisiae: homology of PMS1 to procaryotic MutL and HexB

1989 • 193 citations

Products of DNA mismatch repair genes mutS and mutL are required for transcription-coupled nucleotide-excision repair of the lactose operon in Escherichia coli.

1996 • 174 citations

Escherichia coli mutants uvr D and uvr E deficient in gene conversion of λ-heteroduplexes

1975 • 154 citations

Bidirectional excision in methyl-directed mismatch repair

1993 • 153 citations

DNA-dependent nucleoside 5'-triphosphatase activity of the gene 4 protein of bacteriophage T7.

1983 • 151 citations

Nucleotide excision repair I: from E. coli to yeast

1993 • 122 citations

A preformed, topologically stable replication fork. Characterization of leading strand DNA synthesis catalyzed by T7 DNA polymerase and T7 gene 4 protein.

1983 • 113 citations

Hyper-recombination in uvrD mutants of Escherichia coli K-12

1980 • 111 citations

Escherichia coli helicase II (UvrD) protein initiates DNA unwinding at nicks and blunt ends.

1990 • 103 citations

HYPER-RECOMBINING RECIPIENT STRAINS IN BACTERIAL CONJUGATION

1986 • 98 citations

Overexpression, purification, DNA binding, and dimerization of the Escherichia coli uvrD gene product (Helicase II)

1993 • 90 citations

A Dominant Negative Allele of the Escherichia coli uvrD Gene Encoding DNA Helicase II

1994 • 86 citations

DNA Helicases of Escherichia coli

1991 • 83 citations

Mismatch Repair in Replication Fidelity, Genetic Recombination, and Cancer Biology

1996 • 82 citations

Antipairing and strand transferase activities ofE.colihelicase II (UvrD)

1993 • 76 citations

Construction and analysis of deletions in the structural gene (uvrD) for DNA helicase II of Escherichia coli

1991 • 74 citations

Double helicase II (uvrD)-helicase IV (helD) deletion mutants are defective in the recombination pathways of Escherichia coli

1993 • 68 citations

Mutations in motif II of Escherichia coli DNA helicase II render the enzyme nonfunctional in both mismatch repair and excision repair with differential effects on the unwinding reaction

1995 • 68 citations

Mismatch repair and cancer.

1996 • 61 citations

The DNA binding properties of the MutL protein isolated fromEscherichia coli

1991 • 59 citations

Dual requirement in yeast DNA mismatch repair for MLH1 and PMS1, two homologs of the bacterial mutL gene

1994 • 54 citations

DNA helicases in recombination and repair: construction of a delta uvrD delta helD delta recQ mutant deficient in recombination and repair

1995 • 48 citations

Identification of the gene for DNA helicase II of Escherichia coli

1983 • 42 citations

DNA-Mismatch Repair: The intricacies of eukaryotic spell-checking

1995 • 41 citations

A Point Mutation in Escherichia coli DNA Helicase II Renders the Enzyme Nonfunctional in Two DNA Repair Pathways

1997 • 39 citations

Mutation of a Highly Conserved Arginine in Motif IV ofEscherichia coli DNA Helicase II Results in an ATP-binding Defect

1997 • 30 citations

Microsatellite instability in inherited and sporadic neoplasms

1995 • 15 citations

DNA-replication fidelity, mismatch repair and genome instability in cancer cells

1996 • 12 citations

Direction of the DNA‐unwinding reaction catalysed by Escherichia coli DNA helicase II

1990 • 10 citations

Indirect stimulation of recombination in Escherichia coli K-12: dependence on recJ, uvrA, and uvrD

1991 • 9 citations

Bidirectional excision in methyl-directed mismatch repair

1993 • 5 citations

Mutations in motif II of Escherichia coli DNA helicase II render the enzyme nonfunctional in both mismatch repair and excision repair with differential effects on the unwinding reaction.

1995 • 3 citations

Double helicase II (uvrD)-helicase IV (helD) deletion mutants are defective in the recombination pathways of Escherichia coli.

1993 • 2 citations

Mutation of a Highly Conserved Arginine in Motif IV of Escherichia coli DNA Helicase II Results in an ATP-binding Defect

1997 • 1 citations