Ovariectomy enhances and estrogen replacement inhibits the activity of bone marrow factors that stimulate prostaglandin production in cultured mouse calvariae.

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Involutional Osteoporosis

1986 • 1,873 citations

TIS10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue

1991 • 1,814 citations

A novel arachidonic acid-selective cytosolic PLA2 contains a Ca2+-dependent translocation domain with homology to PKC and GAP

1991 • 1,709 citations

Increased Osteoclast Development After Estrogen Loss: Mediation by Interleukin-6

1992 • 1,437 citations

An interleukin 1 like factor stimulates bone resorption in vitro

1983 • 1,017 citations

The Role of Interleukin-1 in Disease

1993 • 967 citations

ESTERASES IN HUMAN LEUKOCYTES

1973 • 905 citations

Multiple System Organ Failure

1980 • 751 citations

Interleukin-6 deficient mice are protected from bone loss caused by estrogen depletion.

1994 • 738 citations

Blocking IL-1: interleukin 1 receptor antagonist in vivo and in vitro

1991 • 729 citations

PREVENTION OF SPINAL OSTEOPOROSIS IN OOPHORECTOMISED WOMEN

1980 • 705 citations

17 beta-estradiol inhibits interleukin-6 production by bone marrow-derived stromal cells and osteoblasts in vitro: a potential mechanism for the antiosteoporotic effect of estrogens.

1992 • 685 citations

Construction of DNA sequences complementary to rat .alpha.1 and .alpha.2 collagen mRNA and their use in studying the regulation of type I collagen synthesis by 1,25-dihydroxyvitamin D

1984 • 568 citations

Effect of surgical menopause and estrogen replacement on cytokine release from human blood mononuclear cells.

1991 • 558 citations

Prostanoid biosynthesis and mechanisms of action

1992 • 551 citations

Cytosolic phospholipase A2 is coupled to hormonally regulated release of arachidonic acid.

1992 • 546 citations

Cyclooxygenase is an immediate-early gene induced by interleukin-1 in human endothelial cells.

1990 • 484 citations

Induction of cyclooxygenase-2 by interleukin-1 alpha. Evidence for post-transcriptional regulation.

1994 • 478 citations

New insights on mammalian phospholipase A ₂ (s); comparison of arachidonoyl‐selective and ‐nonselective enzymes

1993 • 443 citations

Interleukin-11: a new cytokine critical for osteoclast development.

1994 • 408 citations

Regulation of fibroblast cyclooxygenase synthesis by interleukin-1.

1988 • 401 citations

Alpha and beta human transforming growth factors stimulate prostaglandin production and bone resorption in cultured mouse calvaria.

1985 • 382 citations

Ovarian steroid treatment blocks a postmenopausal increase in blood monocyte interleukin 1 release.

1989 • 381 citations

Effects of Interleukin-1 on Bone Turnover in Normal Mice*

1989 • 366 citations

Sex steroids and bone mass. A study of changes about the time of menopause.

1987 • 346 citations

Interleukin-1 receptor antagonist and tumor necrosis factor binding protein decrease osteoclast formation and bone resorption in ovariectomized mice.

1994 • 341 citations

Interleukin-1 receptor antagonist decreases bone loss and bone resorption in ovariectomized rats.

1994 • 234 citations

Interleukin-1 alpha induces the accumulation of cytosolic phospholipase A2 and the release of prostaglandin E2 in human fibroblasts.

1992 • 230 citations

Estrogen inhibits release of tumor necrosis factor from peripheral blood mononuclear cells in postmenopausal women

1990 • 229 citations

Increased interleukin-6 production by murine bone marrow and bone cells after estrogen withdrawal.

1993 • 184 citations

Multiple System Organ Failure

1991 • 175 citations

Differential regulation of inducible and constitutive prostaglandin endoperoxide synthase in osteoblastic MC3T3-E1 cells.

1993 • 172 citations

Endogenous bone-resorbing factors in estrogen deficiency: Cooperative effects of IL-1 and IL-6

1995 • 160 citations

Natural and recombinant human IL-1 receptor antagonists block the effects of IL-1 on bone resorption and prostaglandin production.

1990 • 154 citations

Stimulation of prostaglandin E2 and bone resorption by recombinant human interleukin 1 alpha in fetal mouse bones

1986 • 140 citations

Regulation of the two prostaglandin G/H synthases by parathyroid hormone, interleukin-1, cortisol, and prostaglandin E2 in cultured neonatal mouse calvariae.

1994 • 117 citations

Interleukin 1 amplifies receptor-mediated activation of phospholipase A2 in 3T3 fibroblasts.

1988 • 110 citations

Stimulation of arachidonic acid metabolism in primary cultures of osteoblast-like cells by hormones and drugs

1984 • 102 citations

Interleukin-1 alpha stimulates prostaglandin biosynthesis in serum-activated mesangial cells by induction of a non-pancreatic (type II) phospholipase A2

1991 • 96 citations

Bone resorptive factor produced by osteosarcoma cells with osteoblastic features is PGE2

1981 • 90 citations

PROSTAGLANDIN PRODUCTION BY CALVARIAE FROM SHAM OPERATED AND OOPHORECTOMIZED RATS: EFFECT OF 17β-ESTRADIOL IN VIVO

1987 • 72 citations

Effects of Parathyroid Hormone and Cortisol on Prostaglandin Production by Neonatal rat Calvaria in Vitro

1985 • 71 citations

Stimulation of prostaglandin e2 production by interleukin-1α and transforming growth factor α in osteoblastic MC3T3-E1 cells

1994 • 65 citations

Mechanism of Regulation of Prostaglandin Production by Parathyroid Hormone, Interleukin-1, and Cortisol in Cultured Mouse Parietal Bones*

1991 • 64 citations

Relationship between interleukin-1 and prostaglandins in resorbing neonatal calvaria

1989 • 64 citations

Inhibition by 17β-estradiol of PTH stimulated resorption and prostaglandin production in cultured neonatal mouse calvariae

1989 • 61 citations

Increased interleukin-6 production by murine bone marrow and bone cells after estrogen withdrawal

1993 • 59 citations

Effect of naproxen on cancellous bone in ovariectomized rats

1990 • 57 citations

92238400 Increased osteoclast development after estrogen loss: Mediation by interleukin-6

1993 • 55 citations

Effect of interleukin 1 beta on osteoblastic clone MC3T3-E1 cells

1988 • 55 citations

Production of both interleukin-lα and ß by newborn mouse calvarial cultures

1990 • 48 citations

Interleukin-1 in Combination with Transforming Growth Factor-α Produces Enhanced Bone Resorptionin Vitro*

1988 • 47 citations

Spontaneous release of interleukin-1 and interleukin-6 by peripheral blood mononuclear cells after oophorectomy

1992 • 42 citations

Effects of transforming growth factor-beta and IL-1 alpha on prostaglandin synthesis in serum-deprived osteoblastic cells.

1991 • 42 citations

Prostaglandins in Bone Resorption

2020 • 29 citations

Regulation of the two prostaglandin G/H synthases by parathyroid hormone, interleukin-1, cortisol, and prostaglandin E2 in cultured neonatal mouse calvariae

1994 • 28 citations

1-Hydroxyethylidene-1,1-bisphosphonate decreases the postovariectomy enhanced interleukin 1 secretion from peritoneal macrophages in adult rats

1991 • 18 citations

Measurement of Interleukin-1 Stimulated Constitutive Prostaglandin G/H Synthase (Cyclooxygenase) mRNA Levels in Osteoblastic MC3T3-E1 Cells Using Competitive Reverse Transcriptase Polymerase Chain Reaction

1994 • 17 citations

Long-term effect of naproxen on cancellous bone in ovariectomized rats

1992 • 16 citations

Blood sample preparation for automated differential systems.

1973 • 12 citations