Multiple System Organ Failure

Shock and Tissue Injury Induced by Recombinant Human Cachectin

1986 • 2,587 citations

Multiple System Organ Failure

1980 • 751 citations

Catecholamines

1974 • 747 citations

Anaphylatoxins: C3a and C5a

1978 • 502 citations

Multiple, Progressive, or Sequential Systems Failure

1975 • 478 citations

Muscle Proteolysis Induced by a Circulating Peptide in Patients with Sepsis or Trauma

1983 • 469 citations

Combined Hormonal Infusion Simulates the Metabolic Response to Injury

1984 • 448 citations

Physiology and Physiopathology of the Reticuloendothelial System

1970 • 412 citations

Pathogenesis of Fever

1960 • 390 citations

Patterns Of Septic Shock In Man—a Detailed Study Of 56 Patients

1967 • 384 citations

Septic Autocannibalism

1980 • 326 citations

Sequential System Failure after Rupture of Abdominal Aortic Aneurysms

1973 • 292 citations

Abnormal Vascular Tone, Defective Oxygen Transport And Myocardial Failure In Human Septic Shock

1967 • 291 citations

Blunt Multiple Trauma (ISS 36), Femur Traction, and the Pulmonary Failure-Septic State

1985 • 289 citations

Physiological and metabolic correlations in human sepsis. Invited commentary.

1979 • 275 citations

Defective oxidative metabolism of rat liver mitochondria in hemorrhagic and endotoxin shock

1971 • 268 citations

Effect of Oral Antibiotics and Bacterial Overgrowth on the Translocation of the GI Tract Microflora in Burned Rats

1985 • 258 citations

Molecular basis of fever in humans

1982 • 252 citations

Physiological and metabolic correlations in human sepsis

1980 • 244 citations

Role of oxygen free radicals in shock, ischemia, and organ preservation.

1983 • 238 citations

Activation of the Properdin Pathway of Complement in Patients with Gram-Negative Bacteremia

1975 • 235 citations

Determinants of death in patients with intraabdominal abscess.

1980 • 234 citations

Remote organ failure: a valid sign of occult intra-abdominal infection.

1977 • 208 citations

Cryoprecipitate Reversal of Opsonic α ₂ -Surface Binding Glycoprotein Deficiency in Septic Surgical and Trauma Patients

1978 • 196 citations

Fever: Pathogenesis, Pathophysiology, and Purpose

1979 • 195 citations

Responses of the ischemic myocardium to allopurinol

1971 • 183 citations

THE ROLE OF OXYGEN FREE RADICALS IN MEDIATING THE REPERFUSION INJURY OF COLD-PRESERVED ISCHEMIC KIDNEYS1,2

1985 • 171 citations

Enterococcal Bacteremia Clinical Implications and Determinants of Death

1982 • 171 citations

Effect of sepsis on activity of pyruvate dehydrogenase complex in skeletal muscle and liver.

1989 • 169 citations

The mechanism of pulmonary damage following traumatic shock.

1970 • 163 citations

PLASMA THROMBOXANE CONCENTRATIONS ARE RAISED IN PATIENTS DYING WITH SEPTIC SHOCK

1982 • 160 citations

Promotion by Burn Stress of the Translocation of Bacteria From the Gastrointestinal Tracts of Mice

1984 • 157 citations

Opsonic Glycoprotein (Plasma Fibronectin) Levels after Burn Injury Relationship to Extent of Burn and Development of Sepsis

1980 • 150 citations

Hormonal Responses and Their Effect on Metabolism

1976 • 148 citations

Re-operation for Intra-abdominal Sepsis

1984 • 147 citations

Opsonic α2 Surface Binding Glycoprotein Therapy During Sepsis

1978 • 146 citations

Both Inflammatory and Endocrine Mediators Stimulate Host Responses to Sepsis

1986 • 146 citations

Multiple Systems Organ Failure: Muscle Fuel Deficit with Visceral Protein Malnutrition

1976 • 137 citations

Cleavage of human interleukin 1: isolation of a peptide fragment from plasma of febrile humans and activated monocytes.

1984 • 136 citations

Exchange of Amino Acids by Muscle and Liver in Sepsis

1983 • 131 citations

Candida Sepsis

1985 • 124 citations

Does drainage of intraabdominal pus reverse multiple organ failure?

1985 • 119 citations

Effect of Endotoxemia on Liver Cell Mitochondria in Man

1970 • 108 citations

DEFICITS IN RETICULOENDOTHELIAL HUMORAL CONTROL MECHANISMS IN PATIENTS AFTER TRAUMA

1976 • 88 citations

Prostacyclin Reversal of Lethal Endotoxemia in Dogs

1981 • 88 citations

Protective effects of thromboxane synthetase inhibitors in rats in endotoxic shock.

1980 • 86 citations

Cardiovascular hemodynamics after opsonic alpha-2-surface binding glycoprotein therapy in injured patients.

1979 • 80 citations

Elevated plasma 6-keto-prostaglandin F1α in patients in septic shock

1985 • 78 citations

Effective organ blood flow and bioenergy status in murine peritonitis.

1986 • 74 citations

Disturbances in circulating opsonic activity in man after operative and blunt trauma

1977 • 61 citations

The induction of interleukin-1 in humans and its metabolic effects.

1985 • 58 citations

Blood and Urinary 17-Hydroxycorticosteroids in Patients with Severe Burns

1956 • 57 citations

Pulmonary Infection Complicating Intra-Abdominal Sepsis

1982 • 57 citations

Systemic Complement Activation Produces Hemodynamic Changes Characteristic of Sepsis

1988 • 51 citations

Hepatic cellular hypoxia in murine peritonitis.

1979 • 50 citations

Hepatocellular function and nutrient blood flow in experimental peritonitis.

1982 • 46 citations

Non-directed relaparotomy for intra-abdominal sepsis. A futile procedure.

1986 • 37 citations

Endorphins in Septic Shock

1982 • 37 citations

Clinical implications in bacteroides bacteremia.

1979 • 35 citations

Disseminated Intravascular Coagulation

1972 • 33 citations

Endotoxin, Cellular Function, and Nutrient Blood Flow

1983 • 31 citations

Atypical clostridial bacteremia.

1981 • 24 citations

The interaction of corticosteroids and naloxone in canine hemorrhagic shock

1982 • 19 citations

The Effect of Indomethacin on Muscle and Liver Protein Synthesis and on Whole-Body Protein Degradation During Abdominal Sepsis in the Rat

1986 • 18 citations

Plasma beta-endorphin immunoreactivity in dogs during anesthesia, surgery, Escherichia coli sepsis, and naloxone therapy.

1983 • 18 citations

Patterns of morbidity and mortality in splenic trauma.

1980 • 18 citations

Alterations of oxygen metabolism in experimental bacteremia.

1981 • 16 citations

Superficial gastric erosions

1973 • 15 citations

Delayed pulmonary clearance of gram-negative bacteria: The role of intraperitoneal sepsis

1979 • 14 citations

Experimental bacteremia and hepatic nutrient blood flow.

1986 • 14 citations

The effects of peritonitis on murine renal mitochondria.

1982 • 12 citations

Imidazole and indomethacin improve hepatic perfusion in sepsis.

1987 • 11 citations

Complement activation in peritonitis. Association with hepatic and renal perfusion abnormalities. First place winner: Conrad Jobst award.

1987 • 11 citations

Infections and Hypocomplementemia

1983 • 8 citations