A Comparison of Mediators Released or Generated by IFN-γ-Treated Human Mast Cells Following Aggregation of FcγRI or FcεRI

Mast cells

1997 • 1,636 citations

F<scp>c</scp>RECEPTOR BIOLOGY

1997 • 1,219 citations

Mast cell modulation of neutrophil influx and bacterial clearance at sites of infection through TNF-α

1996 • 1,121 citations

Critical protective role of mast cells in a model of acute septic peritonitis

1996 • 942 citations

Molecular Basis of Fc Receptor Function

1994 • 523 citations

Demonstration That Human Mast Cells Arise From a Progenitor Cell Population That Is CD34+, c-kit+, and Expresses Aminopeptidase N (CD13)

1999 • 422 citations

Mast cells as sentinels of innate immunity

1999 • 394 citations

IL-12 and IFN-γ in host defense against mycobacteria and salmonella in mice and men

1999 • 333 citations

Impaired mast cell-dependent natural immunity in complement C3-deficient mice

1997 • 283 citations

Purification and characterization of human skin mast cells. Evidence for human mast cell heterogeneity.

1987 • 257 citations

Tyrosine phosphorylation of the gamma subunit of Fc gamma receptors, p72syk, and paxillin during Fc receptor-mediated phagocytosis in macrophages.

1994 • 244 citations

Basophils in bronchial asthma with reference to reagin‐type allergy

1973 • 237 citations

Protein-tyrosine kinase p72syk in high affinity IgE receptor signaling. Identification as a component of pp72 and association with the receptor gamma chain after receptor aggregation.

1993 • 232 citations

Increased production of IFN-γ and cysteinyl leukotrienes in virus-induced wheezing

1999 • 226 citations

Clinical significance of IgG Fc receptors and FcγR-directed immunotherapies

1997 • 221 citations

Mast cells cultured from the peripheral blood of normal donors and patients with mastocytosis originate from a CD34+/Fc epsilon RI- cell population

1994 • 204 citations

Expression of a Functional High-Affinity IgG Receptor, FcγRI, on Human Mast Cells: Up-Regulation by IFN-γ

2000 • 189 citations

Association of the high-affinity receptor for IgG (Fc gamma RI) with the gamma subunit of the IgE receptor.

1993 • 176 citations

A Dominant Role for Mast Cell Fc Receptors in the Arthus Reaction

1996 • 169 citations

Anaphylactic- and calcium-dependent generation of prostaglandin D2 (PGD2), thromboxane B2, and other cyclooxygenase products of arachidonic acid by dispersed human lung cells and relationship to histamine release.

1984 • 168 citations

IgE-dependent expression of mRNA for IL-4 and IL-5 in human lung mast cells.

1995 • 149 citations

Interferon-gamma is necessary for the expression of hypersensitivity pneumonitis.

1997 • 145 citations

Expression of multiple chemokine genes by a human mast cell leukemia.

1994 • 134 citations

Immunopathology and human mast cell cytokines

1999 • 133 citations

Comparative cytokine gene expression: regulation and release by human mast cells

1998 • 123 citations

Physical association between the high-affinity IgG receptor (Fc gamma RI) and the gamma subunit of the high-affinity IgE receptor (Fc epsilon RI gamma).

1993 • 95 citations

Two distinct regions of FC gamma RI initiate separate signalling pathways involved in endocytosis and phagocytosis.

1995 • 94 citations

Functional Separation of Pseudopod Extension and Particle Internalization during Fcγ Receptor–mediated Phagocytosis

1998 • 92 citations

Fey receptors in phagocytes

1998 • 85 citations

Mast Cells Induce Autoantibody-Mediated Vasculitis Syndrome Through Tumor Necrosis Factor Production Upon Triggering Fcγ Receptors

1999 • 70 citations

Assessment of the anti-c-kit monoclonal antibody YB5.B8 in affinity magnetic enrichment of human lung mast cells

1994 • 67 citations

Multifunctional Cytokine Expression by Human Mast Cells: Regulation by T Cell Membrane Contact and Glucocorticoids

1997 • 65 citations

Comparative Cytokine Release from Human Monocytes, Monocyte-Derived Immature Mast Cells, and a Human Mast Cell Line (HMC-1)

1994 • 64 citations

Protein-tyrosine kinase p72syk in Fc gamma RI receptor signaling

1994 • 64 citations

Pathophysiology of human basophils and mast cells in allergic disorders

1989 • 51 citations

A role for mast cells in the development of adjuvant-induced vasculitis and arthritis.

1998 • 45 citations

Inhibition of human mast cell growth and differentiation by interferon gamma-1b.

1998 • 45 citations

Human lung mast cells release small amounts of interleukin-4 and tumour necrosis factor-α in response to stimulation by anti-IgE and stem cell factor

1997 • 42 citations

Reciprocal regulation of cultured human mast cell cytokine production by IL-4 and IFN-γ

2000 • 41 citations

The Cytoplasmic Domain of Human FcγRIa Alters the Functional Properties of the FcγRI·γ-Chain Receptor Complex

1999 • 37 citations

Metabolism of Lipid Mediators in Human Basophils and Mast Cells

1995 • 15 citations

Protein-tyrosine kinase p72syk in Fc gamma RI receptor signaling

1994 • 10 citations