Impaired mast cell-dependent natural immunity in complement C3-deficient mice

The Pathophysiology of Tumor Necrosis Factors

1992 • 1,880 citations

Sepsis and septic shock—A review of laboratory models and a proposal

1980 • 1,441 citations

Mast cell modulation of neutrophil influx and bacterial clearance at sites of infection through TNF-α

1996 • 1,121 citations

Mast cells as a source of both preformed and immunologically inducible TNF-α/cachectin

1990 • 975 citations

Critical protective role of mast cells in a model of acute septic peritonitis

1996 • 942 citations

MOLECULAR ORGANIZATION AND FUNCTION OF THE COMPLEMENT SYSTEM

1988 • 831 citations

Studies of group B streptococcal infection in mice deficient in complement component C3 or C4 demonstrate an essential role for complement in both innate and acquired immunity.

1995 • 496 citations

Disruption of the Cr2 Locus Results in a Reduction in B-1a Cells and in an Impaired B Cell Response to T-Dependent Antigen

1996 • 494 citations

The Proteolytic Activation Systems of Complement

1981 • 479 citations

Antiphosphocholine antibodies found in normal mouse serum are protective against intravenous infection with type 3 streptococcus pneumoniae.

1981 • 477 citations

Impaired IgG-Dependent Anaphylaxis and Arthus Reaction in FcγRIII (CD16) Deficient Mice

1996 • 452 citations

C5A Anaphylatoxin and Its Seven Transmembrane-Segment Receptor

1994 • 418 citations

Regulation of the B cell response to T-dependent antigens by classical pathway complement.

1996 • 369 citations

Release of both preformed and newly synthesized tumor necrosis factor alpha (TNF-alpha)/cachectin by mouse mast cells stimulated via the Fc epsilon RI. A mechanism for the sustained action of mast cell-derived TNF-alpha during IgE-dependent biological responses.

1991 • 369 citations

Systemic anaphylaxis in the mouse can be mediated largely through IgG1 and Fc gammaRIII. Assessment of the cardiopulmonary changes, mast cell degranulation, and death associated with active or IgE- or IgG1-dependent passive anaphylaxis.

1997 • 363 citations

The C5a chemoattractant receptor mediates mucosal defence to infection

1996 • 345 citations

Fc Receptors Initiate the Arthus Reaction: Redefining the Inflammatory Cascade

1994 • 329 citations

The collectins in innate immunity

1996 • 302 citations

Recruitment of neutrophils during IgE-dependent cutaneous late phase reactions in the mouse is mast cell-dependent. Partial inhibition of the reaction with antiserum against tumor necrosis factor-alpha.

1991 • 298 citations

Release of histamine from rat mast cells by the complement peptides C3a and C5a.

1975 • 290 citations

DEFICIENCY OF THE FIFTH COMPONENT OF COMPLEMENT IN MICE WITH AN INHERITED COMPLEMENT DEFECT

1967 • 210 citations

Immunoglobulin G–mediated Inflammatory Responses Develop Normally in Complement-deficient Mice

1996 • 209 citations

IL-6 production by rat peritoneal mast cells is not necessarily preceded by histamine release and can be induced by bacterial lipopolysaccharide.

1994 • 209 citations

COMPLEMENT AS A MEDIATOR OF INFLAMMATION

1967 • 195 citations

COMPLEMENT AS A MEDIATOR OF INFLAMMATION

1967 • 193 citations

Endotoxin shock in antibody-deficient mice: unraveling the role of natural antibody and complement in the clearance of lipopolysaccharide.

1997 • 176 citations

Gross and ultrastructural observations on lesions produced by intradermal injection of human C3a in man.

1970 • 111 citations

Increased susceptibility to endotoxin shock in complement C3- and C4-deficient mice is corrected by C1 inhibitor replacement.

1997 • 105 citations

Augmentation of reverse arthus reaction by mast cells in mice.

1991 • 97 citations

Neutrophil elicitation in the reverse passive Arthus reaction. Complement-dependent and -independent mast cell involvement.

1994 • 49 citations

Specificity of C3 receptors that mediate phagocytosis by rat peritoneal mast cells.

1981 • 31 citations