Translocation and Transcriptional Arrest during Transcript Elongation by RNA Polymerase II

Control of formation of two distinct classes of RNA polymerase II elongation complexes.

1992 • 295 citations

The RNA polymerase II ternary complex cleaves the nascent transcript in a 3'----5' direction in the presence of elongation factor SII.

1992 • 280 citations

Transcription on nucleosomal templates by RNA polymerase II in vitro: inhibition of elongation with enhancement of sequence-specific pausing.

1991 • 239 citations

Factor-stimulated RNA polymerase II transcribes at physiological elongation rates on naked DNA but very poorly on chromatin templates.

1992 • 228 citations

Transcription elongation and eukaryotic gene regulation.

1990 • 227 citations

Transcription Elongation Factor SII (TFIIS) Enables RNA Polymerase II to Elongate through a Block to Transcription in a Human Gene in Vitro

1989 • 189 citations

Discontinuous movements of DNA and RNA in RNA polymerase accompany formation of a paused transcription complex

1995 • 161 citations

Structural analysis of ternary complexes of Escherichia coli RNA polymerase

1992 • 154 citations

Role of the mammalian transcription factors IIF, IIS, and IIX during elongation by RNA polymerase II.

1991 • 152 citations

Discontinuous Mechanism of Transcription Elongation

1994 • 145 citations

Coupling between transcription termination and RNA polymerase inchworming

1995 • 133 citations

RNA polymerase: regulation of transcript elongation and termination

1991 • 127 citations

Analysis of the signals for transcription termination by purified RNA polymerase II

1990 • 113 citations

Regulation of transcriptional elongation by RNA polymerase II

1995 • 111 citations

The active site of RNA polymerase II participates in transcript cleavage within arrested ternary complexes.

1994 • 110 citations

The increment of SII-facilitated transcript cleavage varies dramatically between elongation competent and incompetent RNA polymerase II ternary complexes

1993 • 106 citations

Identification of intrinsic termination sites in vitro for RNA polymerase II within eukaryotic gene sequences

1987 • 97 citations

The RNA polymerase II elongation complex. Factor-dependent transcription elongation involves nascent RNA cleavage.

1992 • 92 citations

Footprinting analysis of mammalian RNA polymerase II along its transcript: an alternative view of transcription elongation.

1991 • 92 citations

Translocation of the Escherichia coli transcription complex observed in the registers 11 to 20: "jumping" of RNA polymerase and asymmetric expansion and contraction of the "transcription bubble".

1995 • 87 citations

Nascent RNA cleavage by arrested RNA polymerase II does not require upstream translocation of the elongation complex on DNA.

1993 • 80 citations

The RNA polymerase II elongation complex

1995 • 62 citations

Cloning, expression and characterization of the human transcription elongation factor, TFIIS

1991 • 54 citations

Contacts between mammalian RNA polymerase II and the template DNA in a ternary elongation complex

1993 • 49 citations

RNA Polymerase II Elongation Complexes Paused after the Synthesis of 15- or 35-Base Transcripts Have Different Structures

1991 • 45 citations