HER-2, gp100, and MAGE-1 Are Expressed in Human Glioblastoma and Recognized by Cytotoxic T Cells

Studies of the HER-2/ neu Proto-Oncogene in Human Breast and Ovarian Cancer

1989 • 6,734 citations

A Gene Encoding an Antigen Recognized by Cytolytic T Lymphocytes on a Human Melanoma

1991 • 3,493 citations

Cancer Regression and Autoimmunity in Patients After Clonal Repopulation with Antitumor Lymphocytes

2002 • 2,781 citations

Use of Tumor-Infiltrating Lymphocytes and Interleukin-2 in the Immunotherapy of Patients with Metastatic Melanoma

1988 • 2,196 citations

Tyrosine Kinase Receptor with Extensive Homology to EGF Receptor Shares Chromosomal Location with neu Oncogene

1985 • 1,804 citations

Identification of a human melanoma antigen recognized by tumor-infiltrating lymphocytes associated with in vivo tumor rejection.

1994 • 921 citations

A listing of human tumor antigens recognized by T cells

2001 • 708 citations

A nonapeptide encoded by human gene MAGE-1 is recognized on HLA-A1 by cytolytic T lymphocytes directed against tumor antigen MZ2-E.

1992 • 694 citations

The activation of human gene MAGE-1 in tumor cells is correlated with genome-wide demethylation.

1996 • 552 citations

Recognition of multiple epitopes in the human melanoma antigen gp100 by tumor-infiltrating T lymphocytes associated with in vivo tumor regression.

1995 • 552 citations

Identification of an immunodominant peptide of HER-2/neu protooncogene recognized by ovarian tumor-specific cytotoxic T lymphocyte lines.

1995 • 542 citations

Vaccination with Tumor Lysate-Pulsed Dendritic Cells Elicits Antigen-Specific, Cytotoxic T-Cells in Patients with Malignant Glioma

2004 • 528 citations

Vaccination of malignant glioma patients with peptide-pulsed dendritic cells elicits systemic cytotoxicity and intracranial T-cell infiltration.

2001 • 501 citations

Adoptive Transfer of Cloned Melanoma-Reactive T Lymphocytes for the Treatment of Patients with Metastatic Melanoma

2001 • 359 citations

Brain tumor survival: results from the National Cancer Data Base.

1998 • 341 citations

Expression of the MAGE-1 tumor antigen is up-regulated by the demethylating agent 5-aza-2'-deoxycytidine.

1994 • 292 citations

Receptor for interleukin 13 is a marker and therapeutic target for human high-grade gliomas.

1999 • 249 citations

Her-2/neu-derived peptides are tumor-associated antigens expressed by human renal cell and colon carcinoma lines and are recognized by in vitro induced specific cytotoxic T lymphocytes.

1998 • 227 citations

Molecular detection of tumor-associated antigens shared by human cutaneous melanomas and gliomas.

1997 • 154 citations

Anti-Tyrosinase-Related Protein-2 Immune Response in Vitiligo Patients and Melanoma Patients Receiving Active-Specific Immunotherapy

1998 • 134 citations

Treatment of recurrent glioma with intracavitary alloreactive cytotoxic T lymphocytes and interleukin-2

1997 • 134 citations

The cancer germ-line genes MAGE-1, MAGE-3 and PRAME are commonly expressed by human myeloma cells

2000 • 122 citations

Identification of a novel HLA-A*0201-restricted, cytotoxic T lymphocyte epitope in a human glioma-associated antigen, interleukin 13 receptor alpha2 chain.

2002 • 121 citations

Immunotherapeutic targeting of shared melanoma-associated antigens in a murine glioma model.

2003 • 118 citations

Targeting Antigen in Mature Dendritic Cells for Simultaneous Stimulation of CD4+ and CD8+ T Cells

2001 • 116 citations

Expression of cancer testis genes in human brain tumors.

2000 • 116 citations

Identification of Her-2/Neu CTL epitopes using double transgenic mice expressing HLA-A2.1 and human CD.8

1997 • 107 citations

Prognostic significance of the c-erbB-2 oncogene product in childhood medulloblastoma

1995 • 107 citations

Generation of high quantities of viral and tumor-specific human CD4+ and CD8+ T-cell clones using peptide pulsed mature dendritic cells

2001 • 103 citations

Expression of MAGE and GAGE in high-grade brain tumors: a potential target for specific immunotherapy and diagnostic markers.

1999 • 90 citations

Major histocompatibility complex class I presentation of exogenous soluble tumor antigen fused to the B-fragment of Shiga toxin

1998 • 80 citations

Molecular and Functional Analysis of Tyrosinase-Related Protein (TRP)-2 as a Cytotoxic T Lymphocyte Target in Patients With Malignant Glioma

2003 • 72 citations

Identification of helper T-cell epitopes that encompass or lie proximal to cytotoxic T-cell epitopes in the gp100 melanoma tumor antigen.

2001 • 71 citations

Prognostic relevance of epidermal growth factor receptor (EGF-R) and c-neu/erbB2 expression in glioblastomas (GBMs)

1993 • 68 citations

Peptide HER2(776–788) represents a naturally processed broad MHC class II-restricted T cell epitope

2001 • 65 citations

Threshold levels of gene expression of the melanoma antigen gp100 correlate with tumor cell recognition by cytotoxic T lymphocytes

2000 • 64 citations

HER-2/neu is expressed in human renal cell carcinoma at heterogeneous levels independently of tumor grading and staging and can be recognized by HLA-A2.1-restricted cytotoxic T lymphocytes

2000 • 60 citations

Vaccination against the HER-2/neu oncogenic protein.

2002 • 57 citations

Human esophageal carcinomas frequently express the tumor-rejection antigens ofMAGE genes

1995 • 53 citations

Retrovirally Transduced Human Dendritic Cells Can Generate T Cells Recognizing Multiple MHC Class I and Class II Epitopes from the Melanoma Antigen Glycoprotein 100

2001 • 53 citations

Expression of neu/c-erbB-2 in human brain tumors

1994 • 49 citations

High frequency of expression of MAGE genes in human hepatocellular carcinoma

1999 • 35 citations

Frequency of MAGE-3 gene expression in HLA-A2 positive patients with non-small cell lung cancer

1998 • 31 citations

Expression of MAGE genes in renal cell carcinoma.

1998 • 27 citations

Gliomas--past, present, and future.

1999 • 19 citations