Molecular and Functional Analysis of Tyrosinase-Related Protein (TRP)-2 as a Cytotoxic T Lymphocyte Target in Patients With Malignant Glioma

Use of Tumor-Infiltrating Lymphocytes and Interleukin-2 in the Immunotherapy of Patients with Metastatic Melanoma

1988 • 2,196 citations

Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease

2002 • 1,510 citations

A Phosphatase Associated with Metastasis of Colorectal Cancer

2001 • 641 citations

A New Era for Cancer Immunotherapy Based on the Genes that Encode Cancer Antigens

1999 • 578 citations

A mutated beta-catenin gene encodes a melanoma-specific antigen recognized by tumor infiltrating lymphocytes.

1996 • 542 citations

Vaccination of malignant glioma patients with peptide-pulsed dendritic cells elicits systemic cytotoxicity and intracranial T-cell infiltration.

2001 • 501 citations

Identification of Tyrosinase-related Protein 2 as a Tumor Rejection Antigen for the B16 Melanoma

1997 • 405 citations

High Avidity CTLs for Two Self-Antigens Demonstrate Superior In Vitro and In Vivo Antitumor Efficacy

1999 • 388 citations

Brain tumor survival: results from the National Cancer Data Base.

1998 • 341 citations

Elucidating the Autoimmune and Antitumor Effector Mechanisms of a Treatment Based on Cytotoxic T Lymphocyte Antigen-4 Blockade in Combination with a B16 Melanoma Vaccine

2001 • 307 citations

Human tumor antigens for cancer vaccine development

1999 • 298 citations

Biodistribution and vaccine efficiency of murine dendritic cells are dependent on the route of administration.

1999 • 283 citations

Identification of TRP-2 as a Human Tumor Antigen Recognized by Cytotoxic T Lymphocytes

1996 • 272 citations

Coupling and Uncoupling of Tumor Immunity and Autoimmunity

1999 • 245 citations

Treatment of intracranial gliomas with bone marrow—derived dendritic cells pulsed with tumor antigens

1999 • 239 citations

Identification of a shared HLA-A*0201-restricted T-cell epitope from the melanoma antigen tyrosinase-related protein 2 (TRP2).

1998 • 199 citations

Regulation of mammalian melanogenesis I: partial purification and characterization of a dopachrome converting factor: dopachrome tautomerase

1990 • 175 citations

Targeting of Lymphotoxin-α to the Tumor Elicits an Efficient Immune Response Associated with Induction of Peripheral Lymphoid-like Tissue

2001 • 172 citations

Molecular detection of tumor-associated antigens shared by human cutaneous melanomas and gliomas.

1997 • 154 citations

Translation of a Retained Intron in Tyrosinase-related Protein (TRP) 2 mRNA Generates a New Cytotoxic T Lymphocyte (CTL)-defined and Shared Human Melanoma Antigen Not Expressed in Normal Cells of the Melanocytic Lineage

1998 • 141 citations

Anti-Tyrosinase-Related Protein-2 Immune Response in Vitiligo Patients and Melanoma Patients Receiving Active-Specific Immunotherapy

1998 • 134 citations

Molecular cloning and functional analysis of a cDNA coding for human DOPAchrome tautomerase/tyrosinase-related protein-2

1994 • 117 citations

Genetic vaccination with 'self' tyrosinase-related protein 2 causes melanoma eradication but not vitiligo

2000 • 116 citations

Expression of cancer testis genes in human brain tumors.

2000 • 116 citations

Expression of MAGE and GAGE in high-grade brain tumors: a potential target for specific immunotherapy and diagnostic markers.

1999 • 90 citations

HLA-Independent Heterogeneity of CD8+ T Cell Responses to MAGE-3, Melan-A/MART-1, gp100, Tyrosinase, MC1R, and TRP-2 in Vaccine-Treated Melanoma Patients

1998 • 86 citations

Pre-Existing Immunity to Tyrosinase-Related Protein (TRP)-2, a New TRP-2 Isoform, and the NY-ESO-1 Melanoma Antigen in a Patient with a Dramatic Response to Immunotherapy

2002 • 73 citations

Therapeutic tumor immunity induced by polyimmunization with melanoma antigens gp100 and TRP-2.

2001 • 69 citations

Use of an in Vitro Immunoselected Tumor Line to Identify Shared Melanoma Antigens Recognized by HLA-A*0201-restricted T Cells

2001 • 64 citations

Tyrosinase-related protein 2 as a mediator of melanoma specific resistance to cis-diamminedichloroplatinum(II): therapeutic implications

2000 • 59 citations

Novel HLA-Cw8-Restricted T Cell Epitopes Derived from Tyrosinase-Related Protein-2 and gp100 Melanoma Antigens

1999 • 52 citations

EGFRvIII as a promising target for antibody-based brain tumor therapy

2000 • 52 citations

Identification of a new HLA-A*0201-restricted T-cell epitope from the tyrosinase-related protein 2 (TRP2) melanoma antigen

2000 • 49 citations

Adoptive immunotherapy of malignant glioma using tumor-sensitized T lymphocytes

1997 • 39 citations

Naturally processed and concealed HLA-A2.1-restricted epitopes from tumor-associated antigen tyrosinase-related protein-2

2000 • 39 citations

T cell-mediated immune responses in melanoma: implications for immunotherapy

2002 • 30 citations

Immunotherapy of malignant brain tumors in children and adults: from theoretical principles to clinical application

1999 • 22 citations

Human tumor-derived genomic DNA transduced into a recipient cell induces tumor-specific immune responsesexvivo

2002 • 21 citations

Tyrosinase Protein Is Expressed Also in Some Neural Crest Derived Cells Which Are Not Melanocytes

1988 • 20 citations

Characterization of B16 melanoma-specific cytotoxic T lymphocytes

1998 • 19 citations

Human Melanocytes and Melanomas Express Novel mRNA Isoforms of the Tyrosinase-Related Protein-2/DOPAchrome Tautomerase Gene: Molecular and Functional Characterization

2000 • 17 citations