A role for eIF4E and eIF4E-transporter in targeting mRNPs to mammalian processing bodies

A new mathematical model for relative quantification in real-time RT-PCR

2001 • 32,396 citations

Decapping and Decay of Messenger RNA Occur in Cytoplasmic Processing Bodies

2003 • 1,323 citations

mRNA stability in mammalian cells

1995 • 1,258 citations

Analysis of gene function in somatic mammalian cells using small interfering RNAs

2002 • 1,108 citations

Automatic measurement of sister chromatid exchange frequency.

1977 • 847 citations

INTERRELATIONSHIPS OF THE PATHWAYS OF mRNA DECAY AND TRANSLATION IN EUKARYOTIC CELLS

1996 • 653 citations

Cytoplasmic foci are sites of mRNA decay in human cells

2004 • 644 citations

Human Dcp2: a catalytically active mRNA decapping enzyme located in specific cytoplasmic structures

2002 • 464 citations

Monitoring protein conformations and interactions by fluorescence resonance energy transfer between mutants of green fluorescent protein

2000 • 407 citations

The human LSm1-7 proteins colocalize with the mRNA-degrading enzymes Dcp1/2 and Xrn1 in distinct cytoplasmic foci

2002 • 387 citations

Förster Distances between Green Fluorescent Protein Pairs

2000 • 360 citations

Identification of a Human Decapping Complex Associated with hUpf Proteins in Nonsense-Mediated Decay

2002 • 355 citations

Messenger RNA Turnover in Eukaryotes: Pathways and Enzymes

2004 • 343 citations

The DEAD box helicase, Dhh1p, functions in mRNA decapping and interacts with both the decapping and deadenylase complexes

2001 • 342 citations

A Mouse Cytoplasmic Exoribonuclease (mXRN1p) with Preference for G4 Tetraplex Substrates

1997 • 341 citations

The hDcp2 protein is a mammalian mRNA decapping enzyme

2002 • 328 citations

Mammalian stress granules represent sites of accumulation of stalled translation initiation complexes

2003 • 268 citations

CCR4, a 3′-5′ poly(A) RNA and ssDNA exonuclease, is the catalytic component of the cytoplasmic deadenylase

2002 • 248 citations

Targeting an mRNA for Decapping

2001 • 233 citations

GW182 is critical for the stability of GW bodies expressed during the cell cycle and cell proliferation

2004 • 205 citations

A novel shuttling protein, 4E-T, mediates the nuclear import of the mRNA 5' cap-binding protein, eIF4E

2000 • 201 citations

mRNA Decapping in Yeast Requires Dissociation of the Cap Binding Protein, Eukaryotic Translation Initiation Factor 4E

2000 • 184 citations

Eukaryotic translation initiation: there are (at least) two sides to every story.

2000 • 138 citations

Nuclear Eukaryotic Initiation Factor 4e (Eif4e) Colocalizes with Splicing Factors in Speckles

2000 • 130 citations

The emerging roles of translation factor eIF4E in the nucleus

2002 • 123 citations

The active form of Xp54 RNA helicase in translational repression is an RNA-mediated oligomer

2004 • 122 citations

The eukaryotic mRNA decapping protein Dcp1 interacts physically and functionally with the eIF4F translation initiation complex

2000 • 89 citations

Molecular Cross-talk between MEK1/2 and mTOR Signaling during Recovery of 293 Cells from Hypertonic Stress

2004 • 57 citations

Modulation of Eukaryotic mRNA Stability via the Cap-binding Translation Complex eIF4F

2002 • 55 citations