The tight interallelic positional coincidence that distinguishes T-cell receptor Jalpha usage does not result from homologous chromosomal pairing during ValphaJalpha rearrangement

Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting

1993 • 984 citations

Association of Transcriptionally Silent Genes with Ikaros Complexes at Centromeric Heterochromatin

1997 • 792 citations

In transgenic mice the introduced functional T cell receptor β gene prevents expression of endogenous β genes

1988 • 374 citations

Intergenic transcription and transinduction of the human β-globin locus

1997 • 334 citations

T cell receptor genes in a series of class I major histocompatibility complex-restricted cytotoxic T lymphocyte clones specific for a Plasmodium berghei nonapeptide: implications for T cell allelic exclusion and antigen-specific repertoire.

1991 • 323 citations

Response to RAG-Mediated V(D)J Cleavage by NBS1 and γ-H2AX

2000 • 315 citations

VDJ recombination

1992 • 307 citations

Regulation of TCR α and β gene allelic exclusion during T-cell development

1992 • 284 citations

Multiple rearrangements in T cell receptor alpha chain genes maximize the production of useful thymocytes.

1993 • 247 citations

How Many Thymocytes Audition for Selection?

1997 • 222 citations

A T cell clone expresses two T cell receptor α genes but uses one αβ heterodimer for allorecognition and self MHC-restricted antigen recognition

1988 • 200 citations

Pleiotropic changes controlled by the pre-T-cell receptor

1999 • 199 citations

T cell receptor gene recombination patterns and mechanisms: cell death, rescue, and T cell production.

1995 • 180 citations

The Human T-Cell Receptor TCRAC/TCRDC (Cα/Cdelta;) Region: Organization, Sequence, and Evolution of 97.6 kb of DNA

1994 • 169 citations

Striking sequence similarity over almost 100 kilobases of human and mouse T–cell receptor DNA

1994 • 159 citations

Defect in Rearrangement of the Most 5′ TCR–Jα Following Targeted Deletion of T Early α (TEA): Implications for TCR α Locus Accessibility

1996 • 158 citations

Different initiation of pre-TCR and γδTCR signalling

2000 • 158 citations

Diversity and joining segments of mouse immunoglobulin heavy chain genes are closely linked and in the same orientation: implications for the joining mechanism.

1983 • 113 citations

T Cell Receptor δ Gene Rearrangement and T Early α (TEA) Expression in Immature αβ LineageThymocytes: Implications for αβ/γδ Lineage Commitment

1996 • 96 citations

Trans-Sensing Effects: The Ups and Downs of Being Together

1998 • 83 citations

Genomic organization of the mouse T cell receptor V alpha family.

1990 • 72 citations

Lack of directed Vα14‐Jα281 rearrangements in NK1⁺ T cells

1997 • 67 citations

Ordered and Coordinated Rearrangement of the TCR α Locus: Role of Secondary Rearrangement in Thymic Selection

2001 • 62 citations

Nonrandom use of J alpha gene segments. Influence of V alpha and J alpha gene location.

1991 • 54 citations

A novel type of aberrant T cell receptor alpha-chain gene rearrangement. Implications for allelic exclusion and the V-J recombination process.

1990 • 50 citations

Analysis of the 1.1-Mb Human α/δ T-Cell Receptor Locus with Bacterial Artificial Chromosome Clones

1997 • 49 citations

Selection and Long-Term Persistence of Reactive CTL Clones During an EBV Chronic Response Are Determined by Avidity, CD8 Variable Contribution Compensating for Differences in TCR Affinities

1999 • 43 citations

Restricted onset of T cell receptor α gene rearrangement in fetal and neonatal thymocytes

1996 • 31 citations

A conserved sequence block in the murine and human TCR J alpha region: assessment of regulatory function in vivo.

1999 • 27 citations

Evidence for recombinatorial hot spots at the T cell receptor Jα locus

1994 • 24 citations

Defect in rearrangement of the most 5′TCR-jα following targeted deletion of T early α (tea): Implications for TCRα locus accessibility

1997 • 22 citations

Molecular Mechanism of Immunoglobulin Class Switch Recombination

1999 • 20 citations

Differential chronology of TCRADV2 gene use by α and δ chains of the mouse TCR

1998 • 19 citations

Preferential ADV-AJ association during recombination in the mouse T-cell receptor alpha/delta locus

2001 • 18 citations

A conserved sequence block in murine and human T cell receptor (TCR) Jα region is a composite element that enhances TCR α enhancer activity and binds multiple nuclear factors

1998 • 16 citations

Deleted Work

1955 • 0 citations