Identification of Molecular Determinants That Are Important in the Assembly of N-Methyl-d-aspartate Receptors

TGF-β SIGNAL TRANSDUCTION

1998 • 7,582 citations

Glutamate receptor ion channels

2005 • 3,667 citations

Blue native electrophoresis for isolation of membrane protein complexes in enzymatically active form

1991 • 2,240 citations

Analysis of Molecular Masses and Oligomeric States of Protein Complexes by Blue Native Electrophoresis and Isolation of Membrane Protein Complexes by Two-Dimensional Native Electrophoresis

1994 • 1,211 citations

Structure of a glutamate-receptor ligand-binding core in complex with kainate

1998 • 672 citations

Structure-activity relationships for amino acid transmitter candidates acting at N-methyl-D-aspartate and quisqualate receptors

1990 • 649 citations

P2X1 and P2X3 receptors form stable trimers: a novel structural motif of ligand-gated ion channels

1998 • 540 citations

Evidence for a Tetrameric Structure of Recombinant NMDA Receptors

1998 • 487 citations

Molecular Determinants of Agonist Discrimination by NMDA Receptor Subunits: Analysis of the Glutamate Binding Site on the NR2B Subunit

1997 • 470 citations

Agonist selectivity of glutamate receptors is specified by two domains structurally related to bacterial amino acid-binding proteins

1994 • 424 citations

Mutational analysis of the glycine-binding site of the NMDA receptor: Structural similarity with bacterial amino acid-binding proteins

1994 • 381 citations

Activation kinetics reveal the number of glutamate and glycine binding sites on the N-methyl-d-aspartate receptor

1991 • 333 citations

Topology profile for a glutamate receptor: Three transmembrane domains and a channel-lining reentrant membrane loop

1995 • 293 citations

The glycine binding site of the N-methyl-D-aspartate receptor subunit NR1: identification of novel determinants of co-agonist potentiation in the extracellular M3-M4 loop region.

1996 • 225 citations

RNA splicing regulates agrin-mediated acetylcholine receptor clustering activity on cultured myotubes

1992 • 212 citations

Identification of Amino Acid Residues of the NR2A Subunit That Control Glutamate Potency in Recombinant NR1/NR2A NMDA Receptors

1998 • 199 citations

Molecular dissection of the agonist binding site of an AMPA receptor.

1995 • 196 citations

Transmembrane topology of two kainate receptor subunits revealed by N-glycosylation.

1994 • 196 citations

Molecular characterization of N-methyl-D-aspartate receptors expressed in mammalian cells yields evidence for the coexistence of three subunit types within a discrete receptor molecule.

1994 • 190 citations

Relationship between N-Methyl-D-aspartate Receptor NR1 Splice Variants and NR2 Subunits

1996 • 156 citations

Protein chemical characterization and immunocytochemical localization of the NMDA receptor subunit NMDA R1.

1993 • 155 citations

Assembly intracellular targeting and cell surface expression of the human N-methyl-d-aspartate receptor subunits NR1a and NR2A in transfected cells

1998 • 152 citations

Determination of NMDA NR1 subunit copy number in recombinant NMDA receptors

1995 • 143 citations

Overexpression of a glutamate receptor (GluR2) ligand binding domain in Escherichia coli : Application of a novel protein folding screen

1997 • 139 citations

Identification of amino acids in the N-methyl-D-aspartate receptor NR1 subunit that contribute to the glycine binding site.

1995 • 137 citations

Molecular determinants of glycine receptor subunit assembly

1999 • 127 citations

Stoichiometry of Recombinant N-Methyl-<scp>d</scp>-Aspartate Receptor Channels Inferred from Single-channel Current Patterns

1997 • 119 citations

Biochemical Evidence for the Co-association of Three N-Methyl-d-aspartate (NMDA) R2 Subunits in Recombinant NMDA Receptors

1999 • 115 citations

Subtype-specific Assembly of α-Amino-3-hydroxy-5-methyl-4-isoxazole Propionic Acid Receptor Subunits Is Mediated by Their N-terminal Domains

1999 • 113 citations

Three-dimensional models of non-NMDA glutamate receptors

1996 • 101 citations

Optimal expression of cloned NMDAR1/NMDAR2A heteromeric glutamate receptors: a biochemical characterization

1993 • 97 citations

Oligomerization and Ligand-binding Properties of the Ectodomain of the α-Amino-3-hydroxy-5-methyl-4-isoxazole Propionic Acid Receptor Subunit GluRD

1999 • 95 citations

The Ionotropic Glutamate Receptors

2001 • 79 citations

Characterization of the Dimerization of Metabotropic Glutamate Receptors Using an N‐Terminal Truncation of mGluR1α

1999 • 77 citations

The Ionotropic Glutamate Receptors

1997 • 76 citations

Structure‐activity analysis of binding kinetics for NMDA receptor competitive antagonists: the influence of conformational restriction

1991 • 76 citations

Recombinant Human NMDA Homomeric NR1 Receptors Expressed in Mammalian Cells Form a High‐Affinity Glycine Antagonist Binding Site

1995 • 68 citations

AMPA receptors and bacterial periplasmic amino acid-binding proteins share the ionic mechanism of ligand recognition

1998 • 66 citations

Expression and Initial Characterization of a Soluble Glycine Binding Domain of the N-Methyl-d-aspartate Receptor NR1 Subunit

1998 • 61 citations

Membrane Topology of the GluR1 Glutamate Receptor Subunit: Epitope Mapping by Site‐Directed Antipeptide Antibodies

1994 • 50 citations

Stable expression and characterization of recombinant human heteromeric N-methyl-D-aspartate receptor subtypes NMDAR1A/2A and NMDAR1A/2B in mammalian cells.

1996 • 45 citations

Blue Native Page as a Useful Method for the Analysis of the Assembly of Distinct Combinations of Nicotinic Acetylcholine Receptor Subunits

1999 • 36 citations

A Molecular Envelope of the Ligand-Binding Domain of a Glutamate Receptor in the Presence and Absence of Agonist

1999 • 33 citations

Expression and characterization of a glycine-binding fragment of the N-methyl-D-aspartate receptor subunit NR1

1999 • 31 citations

Delineation of the Structural Determinants of the N‐Methyl‐D‐Aspartate Receptor Glycine Binding Site

1999 • 2 citations