Structure of a glutamate-receptor ligand-binding core in complex with kainate

[20] Processing of X-ray diffraction data collected in oscillation mode

1997 • 33,348 citations

The CCP4 suite: programs for protein crystallography

1994 • 17,203 citations

Cloned Glutamate Receptors

1994 • 3,989 citations

X-PLOR Version 3.1: A System for X-ray Crystallography and NMR

1992 • 3,488 citations

Flip and Flop: A Cell-Specific Functional Switch in Glutamate-Operated Channels of the CNS

1990 • 1,234 citations

Determination of Macromolecular Structures from Anomalous Diffraction of Synchrotron Radiation

1991 • 1,123 citations

Control of Kinetic Properties of AMPA Receptor Channels by Nuclear RNA Editing

1994 • 735 citations

Autoantibodies to Glutamate Receptor GluR3 in Rasmussen's Encephalitis

1994 • 675 citations

A family of glutamate receptor genes: Evidence for the formation of heteromultimeric receptors with distinct channel properties

1990 • 581 citations

[10] Electron-density map interpretation

1997 • 501 citations

Molecular Determinants of Agonist Discrimination by NMDA Receptor Subunits: Analysis of the Glutamate Binding Site on the NR2B Subunit

1997 • 470 citations

Selective modulation of NMDA responses by reduction and oxidation

1989 • 459 citations

Agonist selectivity of glutamate receptors is specified by two domains structurally related to bacterial amino acid-binding proteins

1994 • 424 citations

N-glycosylation site tagging suggests a three transmembrane domain topology for the glutamate receptor GluR1

1994 • 419 citations

AMPA Receptor Flip/Flop Mutants Affecting Deactivation, Desensitization, and Modulation by Cyclothiazide, Aniracetam, and Thiocyanate

1996 • 343 citations

Phase combination and cross validation in iterated density-modification calculations

1996 • 250 citations

The glycine binding site of the N-methyl-D-aspartate receptor subunit NR1: identification of novel determinants of co-agonist potentiation in the extracellular M3-M4 loop region.

1996 • 225 citations

Molecular dissection of the agonist binding site of an AMPA receptor.

1995 • 196 citations

The structure of glutamine-binding protein complexed with glutamine at 1.94 Å resolution: comparisons with other amino acid binding proteins

1998 • 183 citations

Structural determinants of allosteric regulation in alternatively spliced AMPA receptors

1995 • 164 citations

Identification of the Amino Acid Subsets Accounting for the Ligand Binding Specificity of a Glutamate Receptor

1996 • 120 citations

Identification of Amino Acid Residues that Control Functional Behavior in GluR5 and GluR6 Kainate Receptors

1997 • 118 citations

Three-dimensional models of non-NMDA glutamate receptors

1996 • 101 citations

The macro- and microarchitectures of the ligand-binding domain of glutamate receptors

1998 • 91 citations

[7] Model phases: Probabilities and bias

1997 • 89 citations

Probing the ligand binding domain of the GluR2 receptor by proteolysis and deletion mutagenesis defines domain boundaries and yields a crystallizable construct

1998 • 82 citations

Functional effects of mutations in the putative agonist binding region of recombinant alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors.

1995 • 36 citations

Interdomain salt bridges modulate ligand-induced domain motion of the sulfate receptor protein for active transport

1992 • 16 citations

Ligand recognition in glutamate receptors: insights from mutagenesis of the soluble α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA)-binding domain of glutamate receptor type D (GluR-D)

1997 • 11 citations