Characterization of a full-length cDNA encoding human liver S-adenosylmethionine synthetase: tissue-specific gene expression and mRNA levels in hepatopathies

Molecular cloning: A laboratory manual

1990 • 85,659 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation

1986 • 4,200 citations

Transcription termination and 3′ processing: the end is in site!

1985 • 1,482 citations

The consensus sequence YGTGTTYY located downstream from the AATAAA signal is required for efficient formation of mRNA 3′ termini

1985 • 652 citations

Biological Methylation: Selected Aspects

1975 • 551 citations

S –Adenosyl–L–Methionine Attenuates Alcohol–Induced Liver Injury in the Baboon

1990 • 336 citations

S-adenosyl-L-methionine synthetase and phospholipid methyltransferase are inhibited in human cirrhosis

1988 • 293 citations

Strong cellular preference in the expression of a housekeeping gene of Arabidopsis thaliana encoding S-adenosylmethionine synthetase.

1989 • 242 citations

S-Adenosylmethionine synthetase from Escherichia coli.

1980 • 230 citations

S-Adenosyl-L-Methionine

1989 • 210 citations

Methionine Adenosyltransferase ( S ‐Adenosylmethionine Synthetase) and S ‐Adenosylmethionine Decarboxylase

1984 • 177 citations

Specific loss of the high-molecular-weight form ofS-adenosyl-L-methionine synthetase in human liver cirrhosis

1988 • 168 citations

S –Adenosylmethionine Treatment Prevents Carbon Tetrachloride—Induced S –Adenosylmethionine Synthetase Inactivation and Attenuates Liver Injury

1992 • 160 citations

Induction by fungal elicitor of S-adenosyl-L-methionine synthetase and S-adenosyl-L-homocysteine hydrolase mRNAs in cultured cells and leaves of Petroselinum crispum.

1992 • 159 citations

Oral S-adenosylmethionine in the symptomatic treatment of intrahepatic cholestasis

1990 • 156 citations

Fractionation and kinetic properties of rat liver and kidney methionine adenosyltransferase isozymes

1983 • 146 citations

S-Adenosylmethionine synthetase from human lymphocytes. Purification and characterization.

1985 • 139 citations

Modulation of rat liver S-adenosylmethionine synthetase activity by glutathione.

1992 • 138 citations

SAM2 encodes the second methionine S-adenosyl transferase in Saccharomyces cerevisiae: physiology and regulation of both enzymes.

1988 • 133 citations

Multiple species of mammalian S-adenosylmethionine synthetase. Partial purification and characterization

1981 • 125 citations

Purification and comparison of two forms of S‐adenosyl‐<scp>l</scp>‐methionine synthetase from rat liver

1987 • 124 citations

The sequence of metK, the structural gene for S-adenosylmethionine synthetase in Escherichia coli.

1984 • 108 citations

Activation of methionine for transmethylation. Purification of the S-adenosylmethionine synthetase of bakers' yeast and its separation into two forms.

1977 • 103 citations

Structure and expression analyses of the S-adenosylmethionine synthetase gene family in Arabidopsis thaliana

1989 • 99 citations

Inhibition of glutathione synthesis in the liver leads toS-adenosyl-L-methionine synthetase reduction

1991 • 98 citations

SAM1, the structural gene for one of the S-adenosylmethionine synthetases in Saccharomyces cerevisiae. Sequence and expression.

1987 • 90 citations

S-adenosylmethionine protects against acetaminophen hepatotoxicity in two mouse models

1992 • 81 citations

The synthesis of the two S-adenosyl-methionine synthetases is differently regulated in Saccharomyces cerevisiae

1991 • 76 citations

Complete purification and immunochemical analysis of S-adenosylmethionine synthetase from bovine brain.

1988 • 75 citations

Isolation of a cDNA encoding the rat liver S-adenosylmethionine synthetase

1989 • 75 citations

Molecular cloning and nucleotide sequence of cDNA encoding the rat kidney S-adenosylmethionine synthetase.

1990 • 75 citations

Analysis of the 5′ non‐coding region of rat liver S‐adenosylmethionine synthetase mRNA and comparison of the M_r deduced from the cDNA sequence and the purified enzyme

1991 • 52 citations

Cloning and Nucleotide Sequence of a S-Adenosylmethionine Synthetase cDNA from Carnation

1991 • 49 citations

Inactivation and dissociation ofs-adenosylmethionine synthetase by modification of sulfhydryl groups and its possile occurrence in cirrhosis

1990 • 49 citations

-Adenosylmethionine synthetase isozyme patterns from rat hepatoma induced by -2-fluorenylacetamide

1980 • 44 citations

The role of cysteine-150 in the structure and activity of rat liver S-adenosyl-<scp>l</scp>-methionine synthetase

1991 • 38 citations

Isozymes of S-Adenosylmethionine Synthetase from Rat Liver: Isolation and Characterization1

1986 • 38 citations

How is rat liver S‐adenosylmethionine synthetase regulated?

1992 • 36 citations

SAM2 Encodes the Second Methionine S-Adenosyl Transferase in Saccharomyces cerevisiae: Physiology and Regulation of Both Enzymes

1988 • 35 citations

Identification of the reactive sulfhydryl groups of S-adenosylmethionine synthetase.

1988 • 33 citations

Molecular cloning and nucleotide sequence of cDNA encoding the human liver S-adenosylmethionine synthetase.

1991 • 30 citations

Conversion of rat liver synthetase from high-Mr form to low-Mr form by LiBr

1988 • 30 citations

Mechanisms and Consequences of the Impaired Trans-Sulphuration Pathway in Liver Disease

1990 • 27 citations

Post-transcriptional regulation of S-adenosylmethionine synthetase from its stored mRNA in germinated wheat embryos

1991 • 23 citations