A Sensitive New Method for Rapid Detection of Abnormal Methylation Patterns in Global DNA and within CpG Islands

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands.

1996 • 5,667 citations

Alterations in DNA Methylation: A Fundamental Aspect of Neoplasia

1997 • 1,960 citations

High sensitivity mapping of methylated cytosines

1994 • 1,863 citations

COBRA: a sensitive and quantitative DNA methylation assay

1997 • 1,184 citations

Rapid quantitation of methylation differences at specific sites using methylation-sensitive single nucleotide primer extension (Ms-SNuPE)

1997 • 369 citations

Breaks in genomic DNA and within the p53 gene are associated with hypomethylation in livers of folate/methyl-deficient rats.

1995 • 304 citations

DNA Methylation in Folate Deficiency: Use of CpG Methylase

1993 • 286 citations

Free radical adducts induce alterations in DNAcytosine methylation.

1994 • 282 citations

Increased cytosine DNA-methyltransferase activity is target-cell-specific and an early event in lung cancer.

1996 • 237 citations

DNA adduct 8-hydroxyl-2′-deoxyguanosine (8-hydroxyguanine) affects function of human DNA methyltransferase

1995 • 207 citations

Altered DNA methylation and genome instability: A new pathway to cancer?

1997 • 204 citations

Global DNA hypomethylation in breast carcinoma

1999 • 188 citations

Methylation of the estrogen receptor CpG island in lung tumors is related to the specific type of carcinogen exposure.

1996 • 165 citations

The relationship of DNA methylation to cancer.

1996 • 157 citations

Alterations in hepatic p53 gene methylation patterns during tumor progression with folate/methyl deficiency in the rat

1997 • 156 citations

Increased DNA Methyltransferase Expression Is Associated with an Early Stage of Human Hepatocarcinogenesis

1997 • 96 citations

Aberrant DNA Methylation on Chromosome 16 Is an Early Event in Hepatocarcinogenesis

1996 • 83 citations

Hypomethylation of the rat glutathione S-transferase pi (GSTP) promoter region isolated from methyl-deficient livers and GSTP-positive liver neoplasms

1998 • 39 citations

Perturbation of maintenance and de novo DNA methylation in vitro by UVB (280-340 nm)-induced pyrimidine photodimers.

1985 • 21 citations