Human CD4+CD25+Foxp3+ Regulatory T Cells Do Not Constitutively Express IL-35

Interleukin-12 and the regulation of innate resistance and adaptive immunity

2003 • 3,689 citations

CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells

2006 • 2,516 citations

The inhibitory cytokine IL-35 contributes to regulatory T-cell function

2007 • 1,886 citations

Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells

2006 • 1,496 citations

IL-27, a Heterodimeric Cytokine Composed of EBI3 and p28 Protein, Induces Proliferation of Naive CD4+ T Cells

2002 • 1,401 citations

Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4+CD25– T cells

2003 • 1,252 citations

Foxp3-dependent programme of regulatory T-cell differentiation

2007 • 1,106 citations

FOXP3: Of Mice and Men

2005 • 929 citations

Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3

2007 • 819 citations

Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development

2006 • 773 citations

Discovery and Biology of IL-23 and IL-27: Related but Functionally Distinct Regulators of Inflammation

2006 • 752 citations

Hassall's corpuscles instruct dendritic cells to induce CD4+CD25+ regulatory T cells in human thymus

2005 • 743 citations

Induction of FOXP3 expression in naive human CD4+FOXP3− T cells by T-cell receptor stimulation is transforming growth factor-β–dependent but does not confer a regulatory phenotype

2007 • 730 citations

IL-2 regulates FOXP3 expression in human CD4+CD25+ regulatory T cells through a STAT-dependent mechanism and induces the expansion of these cells in vivo

2006 • 712 citations

WSX-1 and Glycoprotein 130 Constitute a Signal-Transducing Receptor for IL-27

2004 • 674 citations

Effects of IL-13 on phenotype, cytokine production, and cytotoxic function of human monocytes. Comparison with IL-4 and modulation by IFN-gamma or IL-10.

1993 • 657 citations

Cutting Edge: Direct Suppression of B Cells by CD4+CD25+ Regulatory T Cells

2005 • 578 citations

IL‐35 is a novel cytokine with therapeutic effects against collagen‐induced arthritis through the expansion of regulatory T cells and suppression of Th17 cells

2007 • 562 citations

The role of 2 FOXP3 isoforms in the generation of human CD4+ Tregs

2005 • 439 citations

Human CD8+CD25+ thymocytes share phenotypic and functional features with CD4+CD25+ regulatory thymocytes

2003 • 388 citations

Phenotype, Localization, and Mechanism of Suppression of CD4+CD25+ Human Thymocytes

2002 • 384 citations

A novel interleukin-12 p40-related protein induced by latent Epstein-Barr virus infection in B lymphocytes

1996 • 327 citations

Epstein–Barr virus-induced gene 3 and the p35 subunit of interleukin 12 form a novel heterodimeric hematopoietin

1997 • 308 citations

Is FOXP3 a bona fide marker for human regulatory T cells?

2008 • 168 citations

Expression of IL‐27 in human Th1‐associated granulomatous diseases

2004 • 135 citations

The biology and therapeutic potential of interleukin 27

2007 • 126 citations

Differential Effects of IL-27 on Human B Cell Subsets

2006 • 107 citations

Expression of Epstein-Barr Virus-Induced Gene 3, an Interleukin-12 p40-Related Molecule, throughout Human Pregnancy

2001 • 100 citations

Frequent expression of the Epstein–Barr virus (EBV)‐induced gene, EBI3, an IL‐12 p40‐related cytokine, in Hodgkin and Reed–Sternberg cells

2002 • 98 citations

Analysis of Interleukin-27 (EBI3/p28) Expression in Epstein-Barr Virus- and Human T-Cell Leukemia Virus Type 1-Associated Lymphomas

2005 • 68 citations

Expression of Interleukin-27 by Human Trophoblast Cells

2007 • 42 citations

Variable expression of Epstein–Barr virus-induced gene 3 during normal B-cell differentiation and among B-cell lymphomas

2006 • 31 citations